Ibiranga ikoranabuhanga ryinshi rya hydroxyproppopyl methylcellse

HydroxyPropyl Methylcellse (HPMC)Nibikoresho byingenzi bya shimi, bikoreshwa cyane mubikoresho byubaka, imiti, ibiryo nibindi bice. Cyane cyane mu nganda zubwubatsi, HPMC ikoreshwa cyane kubera imikorere myiza yacyo. Ikoranabuhanga ryo hejuru rifite uruhare runini mu gukora no gukoresha HPMC.

1. Uruhare rw'ikoranabuhanga ry'ubushyuhe bukabije muri HPMC

Umusaruro WorxyPropyl MethylcellPellse aboneka hamwe nuburyo bwa chimique nko muri alkalisation no guhinduranya selile kamere. Ikoranabuhanga ryo hejuru ryinshi rikoreshwa cyane muri selisolution, ryumisha kandi ryibumba ryimikorere. Kuvura ubushyuhe bwinshi ntibushobora kwihutisha gusa igipimo cya reaction, ariko nanone kunoza ubuziranenge no gutuza kubicuruzwa.

Kunoza Urufatiro

Muburyo bwo hejuru cyane, igipimo cyimyitwarire ya selile na sodium byihuta, biteza imbere ibisubizo bya hydroxyPropy na methyl byinjira muri molekile, bityo bigatuma urugero rwo gusimbuza (DS) nuburyo bumwe bwa HPMC.

Kuraho umwanda

Ubushyuhe bwo hejuru burashobora kuvanaho ibicuruzwa byakozwe neza mugihe cyimyitwarire mugihe cya alkali bidasubirwaho no gukemurwa, no kuzamura isuku ya HPMC.

Kunoza imikorere yumye

Mugihe cyo gukama cyane, ubuhehere bwa HPMC buhumura vuba, twirinda ibicuruzwa bikabije cyangwa kwamagana ubushyuhe buke, no kuzamura umutekano nubukungu nububiko bwibicuruzwa.

2. Ingaruka z'ubuhanga bwo hejuru cyane ku mikorere ya HPMC

Ikoranabuhanga ryinshi rigira ingaruka gusa kumiterere ya HPMC, ariko nanone ifite ingaruka zikomeye kumiterere ya miti yimiti ningaruka zisaba.

Guhindura vicosity

Inzira yubushyuhe bwinshi ntizishobora kugenzura neza ibipimo bya molecra yo gukwirakwiza HPMC, bityo guhinduranya ubuyobe bwayo. Ubushyuhe bwo hejuru bufasha kugabanya amahirwe yo kuruhuka molecular, gukora vicosi ya HPMC mu gisubizo gihamye.

Kuzamura Ubushyuhe

Ubushyuhe bwa Lurmal bwa HPMC bwateye imbere cyane binyuze mubuvuzi bwimbitse. Mu kubaka minisiteri na Tile, HPMC irashobora gukomeza gukomera neza no kugandukira imitungo yo kurwanya ubushyuhe burimo ubushyuhe bwinshi.

Iterambere

Mugihe cyo kumisha ubushyuhe bwo hejuru, microstrokere ya HPMC irateguwe, ikagira byinshi mumazi akonje. Cyane cyane mubushyuhe buke-bwubwubatsi, HPMC irashobora gushonga vuba kandi ikora igisubizo kimwe cya colloidal.

3. Gushyira mu bikorwa tekinoroji yubushyuhe bwo hejuru mumikorere ya HPMC

Guhanga

Mugukora reteaction ku bushyuhe bwo hejuru bwa 80-100 ° C, usimburwa n'amatsinda ya hydroxyPropyl na methyleproppepy na methylproppepy na methyl of troproppofy na methyl irashobora kwihuta, kugirango HPMC ifite urwego rwo hejuru rwo gusimbuza kandi ruhamye.

Kumisha no kumenagura icyiciro

Ikoranabuhanga rishyushye ryumukino hejuru ya 120 ° C ridashobora gukuraho ubushuhe gusa, ahubwo rinakubuza ifu ya HPMC kuva mu makimbirane yo gukama. Nyuma yaho, hakoreshwa tekinoroji yo kumenagura ubushyuhe ikoreshwa mugukora ifu ya HPMC yoroshye kandi isamo, kandi ibitagenda neza bitera imbere.

Ubushyuhe bwinshi bwo kuvura

Iyo HPMC ikoreshwa mubikoresho byo kubaka cyangwa kurera, kuvura ubushyuhe bwinshi birashobora kuzamura imitako ya sag, imikorere yo kurwanya ya sag no kugumirwa no kugumana amazi, kugenzura ingaruka nziza mubwubatsi mubidukikije bikaze.

4. Ibyiza byubushyuhe bwinshi bwikoranabuhanga muri HPMC

Ibikoresho byo kubaka

Ku bushyuhe bwo hejuru, HPMC yerekana ubwinshi no kugumana amazi mu mazi na prowder, kubuza minisiteri kuva mu butayu bwa vuba no gucika intege.

Inganda

HPMC synthesised yubushyuhe bwinshi ifite urwego rwiza kandi rwo kurwanya runini mu irangi rya latex, ritera imbaraga kandi zikanga kurwanya ipfundo.

Inganda za farumasi

Ikoranabuhanga ryinshi ryibihemba birashobora kuzamura uburinganire bwa HPMC mubiti bikwira ibiyobyabwenge no kwemeza ko ibiyobyabwenge bihamye bikaborora.

Gushyira mu bikorwa tekinoroji yubushyuhehydroxypropyl methylcellseNtabwo arimura gusa imikorere yumusaruro, ariko kandi izamura ibicuruzwa. Binyuze mu bushyuhe bwo hejuru, viscosity, gucika intege na HPMC byateguwe cyane, bigatuma iba ifite ibyiringiro byagutse mu mirima yo kubaka, amatara n'imiti. Mu bihe biri imbere, hamwe no guhanga udushya twihangano bukabije bwimikorere, imikorere ya HPMC izakomeza kuba nziza, ikagira uruhare runini mugutezimbere ibikoresho byibidukikije nibidukikije.