Ibisubizo byimiti muri fermentation ya hydroxypropyl methylcellse

HydroxyPropyl Methylcellse (HPMC)Ese amazi ya polymer akoreshwa mu nganda zisanzwe mu nganda n'ubuvuzi, kandi ifite indangagaciro zitandukanye, nko mu kurekura ibiyobyabwenge, ibikoresho byo gutunganya ibiryo n'ibikoresho. Imiti yimiti mubikorwa byayo fermentation ifitanye isano ahanini no gutesha agaciro no guhinduranya selile nibikorwa bya metabolike bya mikorobe. Kugirango twumve neza imiti ya HPMC muburyo bwo gusebanya, dukeneye kubanza gusobanukirwa imiterere yacyo hamwe nuburyo bwo gutesha agaciro.

1. Imiterere y'ibanze n'imitungo ya hydroxypropyl methylcellse

HPMC ni ukuvazwa kuboneka kubishushanyo mbonera bya selile karemano (selile). Umugongo wumurongo wacyo ni molekile ya glucose (c6h12o6) ihujwe na β-1,4 glycosic. Cellulose ubwayo biragoye gushonga mumazi, ariko mu kumenyekanisha Methyl (-OCH3) na hydroxyPropyl (-C3h7Oh), amazi yonyine arashobora kunozwa cyane kugirango akore polymer. Inzira yo guhindura HPMC ikubiyemo reaction ya selile hamwe na methyl chloride (ch3cl) na prostayo (c3h6o) mubihe bya alkaline bifite hydrofiliri yindabyo kandi yonyine.

2. Ibisubizo byimiti mugihe fermentation

Inzira ya fermentation ya HPMC isanzwe biterwa nigikorwa cya mikorobe, ikoresha HPMC nkisoko yintungamubiri nintungamubiri. Inzira ya fermentation ya HPMC ikubiyemo ibyiciro byingenzi bikurikira:

2.1. Gutesha agaciro HPMC

Cellulose ubwayo igizwe n'ibice bya Glucose bahujwe na mikorondari mugihe cya feri ya feriganwa, kubora kwa mbere mu masuka akoreshwa (nka glucose, na xylose, nibindi). Iyi nzira mubisanzwe ikubiyemo ibikorwa bya extrase nyinshi zitesha agaciro. Imyitwarire nyamukuru yateguwe harimo:

Ubugari bwa Cellrolysis: β-1,4 Glycosic Bonds Mounds izavunika na Hydrolases (nka selile, itanga iminyururu ngufi (nka olistacchaside, nibindi). Aya masoko azakomeza kuba metabolize kandi akoreshwa na mikorobe.

Hydrolysis hamwe no gutesha agaciro HPMC: Methyl na HydroxyPropoyl basimbuye muri molekile ya HPMC ikurwaho igice na hydrolysis. Uburyo bwihariye bwimyitwarire ya hydrolysis ntikirasobanuka neza, ariko birashobora gutuma ibyo mubidukikije, imyitwarire ya hydrolysis irasabwe na enzymes ihinduka na mikorobe (nka hydroxyl esterase). Iyi mikorere iganisha ku minyururu ya HPMC no gukuraho amatsinda yimikorere, amaherezo akora molekile ntoya.

2.2. Microbial Metabolic reaction

HPMC imaze guteshwa agaciro k'imisumari, mikorobe irashobora guhindura ingufu mu mbaraga binyuze mu buryo bunoze. By'umwihariko, mikorobe itangiza glucole muri ethanol, aside lactic cyangwa izindi metabolite binyuze mu nzira ya fermentation. Mikorobe zitandukanye irashobora metabolize ibicuruzwa byangiza hpmc binyuze munzira zitandukanye. Inzira isanzwe ya metabolic ikubiyemo:

Glycolysis Patray: Glucose irabonwa muri Pyruvate na Enzymes kandi ihinduka ingufu (ATP) na metabolite (nka aside ya lactique, ethanol, nibindi).

Igisekuru cya fermentation: Munsi ya Anaerobic cyangwa hypoxisms, mikorobe ihindura glucose cyangwa ibicuruzwa byangiza, nibindi bikoreshwa munzira nziza.

2.3. Redox reaction

Mugihe cya HPMC ya HPMC, mikorobe imwe irashobora guhindura ibicuruzwa hagati binyuze mubyo reaction. Kurugero, inzira yo gukora ya Ethanol iherekejwe na reaction ya Redox, Glucose ni okiside yo kubyara, hanyuma pyruvate ihindurwa muri Ethanol binyuze mu kugabanya. Ibi bitekerezo ni ngombwa mugukomeza kuringaniza metabolic ya selile.

3. Kurwanya ibintu muri fermentation

Mugihe cya fermentation ya HPMC, ibintu bidukikije bifite ingaruka zikomeye kubitekerezo bya shimi. Kurugero, PH, ubushyuhe, ibishishwa bya ogisijeni, ihungabana ryibandaho, nibindi bizagira ingaruka kumiterere ya metabolic ya mikorobe nubwoko bwibicuruzwa. By'umwihariko ubushyuhe na pH, ibikorwa bya microbial enzymes birashobora gutandukana cyane mubushyuhe butandukanye hamwe nuburyo bwa PH, ni ngombwa rero ko bitesha agaciro HPMC hamwe nuburyo bworoshye bwimiterere ya mikorobe.

Inzira ya fermentation yaHpmcHarimo imiti igoye, harimo hydrolysis ya selile, kwangirika kwa HPMC, metabolism yisumari, hamwe nigisekuru cyibicuruzwa bisebanya. Gusobanukirwa ibi bitekerezo ntabwo bifasha gusa kunoza inzira ya HPMC, ariko kandi itanga inkunga idasanzwe yumusaruro ujyanye n'inganda. Hamwe no kwimbitse ubushakashatsi, uburyo bunoze kandi bwubukungu bushobora gutezwa imbere mugihe cyo kunoza uburyo bwo gutesha agaciro HPMC numusaruro wibicuruzwa, kandi bigateza imbere ikoreshwa rya HPMC, kurinda ibidukikije nibindi bidukikije.