HydroxyPropyl Methylcellse (HPMC)ni ukoreshwa mu mazi ya polymer polymer, akoreshwa cyane muri farumasi, ibiryo, ibikoresho byo kubaka, kwisiga hamwe nizindi nzego. HPMC ifite ibiranga neza kandi iranga viscometity kandi irashobora gukora igisubizo gihamye cya colloidal, niko bigira uruhare runini muri porogaramu nyinshi. Kugirango utange ibintu byuzuye kubikorwa bya HPMC, uburyo bukwiye bwo kutuvumburwa ni ngombwa cyane.
1. Ubushyuhe busanzwe bwo kuvura amazi
HPMC irashobora gushonga mumazi akonje, ariko mubisanzwe ubuhanga bumwe burakenewe kugirango twirinde guterana. Kugirango utezimbere ingaruka zo gusebanya, intambwe zikurikira zirashobora gukoreshwa:
Intambwe ya 1: Ongeraho HPMC kumazi
Ku bushyuhe bwicyumba, bwambere kuminjagira kuri epmly hejuru yamazi kugirango wirinde gusuka hpmc nyinshi mumazi icyarimwe. Kuberako HPMC ari compound yo muri polymer, yongereranya na HPMC nyinshi zizayitera gukuramo amazi no kubyimba mumazi kugirango ukore ibintu nka gel.
Intambwe ya 2: Gushishikaza
Nyuma yo kongeraho HPMC, komeza ubyuke neza. Kuberako HPMC ifite ibice byiza, bizabyimba nyuma yo gukuramo amazi kugirango ukore ibintu nkibintu bisa na gel. Gukurura bifasha gukumira HPMC kuva kugarizwa mubice.
Intambwe ya 3: Hagarara hanyuma uhagarare
Niba HPMC idasenyutse rwose, igisubizo kirashobora gusigara guhagarara mugihe gito hanyuma ugakomeza kubyutsa. Mubisanzwe bizashonga rwose mumasaha make.
Ubu buryo burakwiriye ibihe aho gushyushya bitasabwa, ariko bisaba igihe kirekire kugirango HPMC isenyutse rwose.
2. Uburyo bushyushye bwamazi
HPMC irashonga vuba mumazi ashyushye, gushyushya ubushyuhe bwamazi birashobora kwihutisha cyane inzira yo kuvuka. Gukoreshwa gushyushya ubushyuhe bwamazi ni 50-70 ℃, ariko hejuru cyane (nko hejuru ya 80 ℃) birashobora gutera HPMC kugirango biteshe agaciro, bityo ubushyuhe bugomba kugenzurwa.
Intambwe ya 1: Gushyushya amazi
Shyushya amazi kugera kuri 50 ℃ kandi uhoraho.
Intambwe ya 2: Ongeraho HPMC
Kunyanyagiza HPMC buhoro mumazi ashyushye. Kubera ubushyuhe bwo hejuru, HPMC izashonga byoroshye, kugabanya agglomeration.
Intambwe ya 3: Gushishikaza
Nyuma yo kongeraho HPMC, komeza ukangura igisubizo cyibitangaza. Ihuriro ryo gushyushya no gukangurira rirashobora guteza imbere imvururu yihuse ya HPMC.
Intambwe ya 4: Komeza ubushyuhe kandi ukomeze kubyutsa
Urashobora kugumana ubushyuhe runaka ugakomeza kubyutsa kugeza HPMC ishonga rwose.
3. Uburyo bwo kuvura inzoga
HPMC irashobora gushose mumazi gusa, ariko no muri alcovents (nka Ethanol). Inyungu nyamukuru yuburyo bwo kuvura inzoga ni uko bishobora kunonosora kwa HPMC, cyane cyane kuri sisitemu hamwe namazi menshi.
Intambwe ya 1: Hitamo inzoga zikwiye
Inzoga zidakemu nka Ethanol na isopropanol zikoreshwa mugushonga HPMC. Muri rusange, 70-90% igisubizo cya Ethanol gifite ingaruka nziza kuri HPMC.
Intambwe ya 2: Dissolution
Buhoro buhoro uminyuke HPMC mu nzoga, ukomeretsa mugihe wongeyeho kugirango HPMC yatatanye neza.
Intambwe ya 3: Guhagarara no gukangurira
Inzira ya alcool solvel isesa hpmc ihagaze neza, kandi mubisanzwe ifata iminota mike kugirango ikoreshwe burundu.
Uburyo bw'inzovu bukoreshwa mu buryo busanzwe bukoreshwa mu buryo bwo gusaba bisaba gusenya byihuse n'amazi make.
4. Umuyoboro-amazi avanze
Rimwe na rimwe, HPMC ishonga mu ruvange rw'umunyagihugu runaka w'amazi na Solven. Ubu buryo bubereye cyane cyane ibihe aho bigaragara ko igisubizo cyangwa igipimo cyo gusenya kigomba guhinduka. Ibicuruzwa bisanzwe birimo Acetone, Ethanol, nibindi
Intambwe ya 1: Tegura igisubizo
Hitamo ikigereranyo gikwiye cyamazi n'amazi (urugero 50% amazi, 50% Solven) nubushyuhe kubushyuhe bukwiye.
Intambwe ya 2: Ongeraho HPMC
Mugihe ushishikaje, ongeraho HPMC kugirango iseswa rimwe.
Intambwe ya 3: Ibindi Byahinduwe
Nkuko bikenewe, umubare wamazi cyangwa socven birashobora kwiyongera kugirango uhindure umukecuru no gusya ya HPMC.
Ubu buryo burakwiriye mugihe ibintu bivuga ko ibiti bya kama byongewe kubisubizo bitangaje kugirango utezimbere igipimo cyo gusenyuka cyangwa guhindura imitungo yigiti.
5. Ultrasonic-Afashijwe nuburyo bwo kuvugurura
Gukoresha Ingaruka-nyinshi zo hejuru za ultrasound, uburyo bwo kuvura ultrasonic-bufashanya burashobora kwihutisha gahunda yo gusebanya ya HPMC. Ubu buryo bukwiranye cyane cyane na HPMC nyinshi zigomba gushonga vuba, kandi zirashobora kugabanya ikibazo cya agglomeration gishobora kubaho mugihe gitunguranye.
Intambwe ya 1: Tegura igisubizo
Ongeraho HPMC kumazi akwiye cyangwa yamazi avanze igisubizo.
Intambwe ya 2: Kuvura Ultrasonic
Koresha isuku ya Ultrasonic cyangwa inzara ya ultrasonic kandi iyifate ukurikije imbaraga nigihe. Ingaruka ya Oscaciund irashobora kwihutisha cyane inzira yo gusebanya ya HPMC.
Intambwe ya 3: Reba ingaruka zo gusebanya
Nyuma yo kuvura ultrasonic, reba niba igisubizo gishonga rwose. Niba hari igice kidasubirwaho, kuvura ultrasonic birashobora kongera gukorwa.
Ubu buryo burakwiriye kubisabwa bisaba gusenya neza kandi byihuse.
6. Pretreatent mbere yo gusesa
Kugirango wirindeHpmcGutera imbaraga cyangwa ingorane zo gushonga, uburyo bumwe bwo kwisiga burashobora gukoreshwa, nko kuvanga hpmc hamwe nubundi buryo butandukanye (nka glycerol), kumisha bwa mbere, cyangwa guswera bwa mbere mbere yo kongeramo possi. Izi ntambwe zo guhitamo zirashobora kunoza neza ibyo HPMC.
Hariho inzira nyinshi zo gusesa HPMC. Guhitamo uburyo bukwiye bwo kutuvumburwa burashobora kunoza uburyo bwo kuvura no gutanga umusaruro. Uburyo bwo kuvura ubushyuhe bukwiranye n'ibidukikije byoroheje, uburyo bw'amazi ashyushye burashobora kwihutisha gahunda yo gusebanya, hamwe nuburyo bwo kuvura inzoga hamwe n'amazi atandukanye nuburyo bukenewe. Uburyo bwo kuvura ultrasonic-bufasha uburyo bwiza bwo gukemura ibisebe byihuse bya HPMC. Ukurikije ibisabwa byihariye bisabwa, guhitamo byoroshye muburyo bukwiye bushobora kwemeza imikorere myiza ya HPMC mumirima itandukanye.
Igihe cyagenwe: Ukuboza-19-2024