1. Imiterere y'ibanze ya HPMC
HydroxyPropyl Methylcellse (HPMC)Ese selile idafite ubumwe zikoreshwa cyane mubikoresho byubaka, imiti, ibiryo, kwisiga nizindi nganda. Ibintu byayo byihariye bya miralecicticalicalique, nko kwishyurwa, kubyimba, gushiraho filime hamwe nubushyuhe bwamabuye, bikaba ari ikintu cyingenzi mubisabwa byinganda. Ubushyuhe nimwe mubintu nyamukuru bireba imikorere ya HPMC, cyane cyane mubijyanye no kwikeba, victosity, pelation yubushyuhe hamwe nubushyuhe.
2. Ingaruka z'ubushyuhe kuri relubility ya HPMC
HPMC ni polymer yoroheje, kandi ihinduka ryayo nubushyuhe:
Ubushyuhe buke (amazi akonje): HPMC irashonje byoroshye mumazi akonje, ariko bizakurura amazi hanyuma ikabyimba iyo isabana bwa mbere amazi kugirango akore inshinge. Niba gukangurira bidahagije, ibibyimba birashobora gushiraho. Kubwibyo, mubisanzwe birasabwa kongeramo HPMC buhoro mugihe uhindagurika kugirango uteze imbere gutatanya kimwe.
Ubushyuhe buciriritse (20-40 ℃): Muri ubu bushyuhe, HPMC ifite ubwitonzi bwiza kandi bukwiriye sisitemu zitandukanye bisaba kubyimba cyangwa guturika.
Ubushyuhe bwo hejuru (hejuru ya 60 ° C): HPMC ikunda gukora gel ishyushye ku bushyuhe bwinshi. Iyo ubushyuhe bugera ku bushyuhe bwihariye bwa Gel, igisubizo kizaba Optaque cyangwa kikanatera, bigira ingaruka ku ngaruka zisaba. Kurugero, mubikoresho byo kubaka nka minisiteri cyangwa ifu ya minisiteri, niba ubushyuhe bwamazi ari hejuru cyane, HPMC ntishobora gushonga neza, bityo igashonga neza, bityo igira ingaruka kumiterere yubwubatsi.
3. Ingaruka z'ubushyuhe kuri vicosity ya HPMC
Ubukwe bwa HPMC bugira ingaruka ku bushyuhe:
Kongera ubushyuhe, kugabanuka kuri viscosity: viscosiya igisubizo cya HPMC mubisanzwe iragabanuka hamwe nubushyuhe. Kurugero, viscosiya igisubizo runaka cya HPMC gishobora kuba kinini kuri 20 ° C, mugihe kuri 50 ° C, visosi yacyo izagabanuka cyane.
Ubushyuhe bugabanuka, abasura bakira: Niba igisubizo cya HPMC gikonje nyuma yo gushyushya, ubushyuhe bwayo buzakira igice, ariko ntibishobora gusubira muri leta ya mbere.
HPMC yamanota atandukanye yitwara muburyo butandukanye: Hejuru-viscosity HPMC yunvikana cyane nubushyuhe, mugihe HPMCY HPMC ifite ihindagurika rito mugihe ubushyuhe buhindutse. Kubwibyo, ni ngombwa cyane guhitamo HPMC hamwe na vino nziza muburyo butandukanye.
4. Ingaruka z'ubushyuhe kuri petile ya HPMC
Ikintu cyingenzi cya HPMC ni pelation yubushyuhe, ni ukuvuga, igihe ubushyuhe buzamuka kurwego runaka, igisubizo cyacyo kizahinduka gel. Ubu bushyuhe busanzwe bwitwa ubushyuhe bwa gelale. Ubwoko butandukanye bwa HPMC ifite ubushyuhe butandukanye bwa pelasiyo, muri rusange hagati ya 50-80 ℃.
Mu biribwa n'inganda za farumasi, ibi biranga HPMC ikoreshwa mugutegura ibiyobyabwenge byakomeje-birekura ibiyobyabwenge cyangwa ibiryo.
Mubikorwa byubatswe, nka CEMES MORTAR na PAOLD ifu, pelate yubushyuhe bwa HPMC irashobora gutanga ihohoterwa rishingiye ku mazi, ariko niba ubushyuhe bwibidukikije burebure cyane, pelation irashobora kugira ingaruka ku gikorwa cy'ubwubatsi.
5. Ingaruka z'ubushyuhe kuri Sthermal ituje rya HPMC
Imiterere yimiti ya HPMC ihagaze neza mubushyuhe bukwiye, ariko kuramba kugeza ubushyuhe bwinshi bushobora guteza amahano.
Ubushyuhe buke (nko gushyushya ako kanya kugeza hejuru 100 ℃): Ntishobora kugira ingaruka zikomeye kumiterere ya HPMC, ariko irashobora guhindura ibintu mumitungo ya HPMC, ariko irashobora guhindura ibintu byumubiri bya HPMC, ariko birashobora gutera impinduka mumitungo yumubiri, nko kugabanuka.
Ubushyuhe burebure (nko gusiga hejuru hejuru ya 90 ℃): birashobora gutuma urunigi rwa HPMC ruvamo, bikaviramo kugabanuka bidasubirwaho muri viscosity, bigira ingaruka kumiterere yacyo na film.
Ubushyuhe bukabije (hejuru ya 200 ℃): HPMC irashobora kubyanganiza ubushyuhe, kurekura ibintu bihindagurika nka methanol na propanol, kandi bigatera ibikoresho cyangwa bikagenda.
6. Ibyifuzo byo gusaba HPMC mubushyuhe butandukanye
Kugirango utange umukino wose mubikorwa bya HPMC, hagomba gufatwa ingamba zikwiye zigomba gufatwa ukurikije ubushyuhe butandukanye:
Mu bushyuhe buke (0-10 ℃): HPMC irashonga buhoro, kandi irasabwa kubanza gusezerera mumazi ashyushye (20-40 ℃) mbere yo gukoreshwa.
Mu bushyuhe busanzwe (10-40 ℃): hpmc ifite imikorere ihamye kandi ibereye ikoreshwa cyane, nko kurema, minisiteri, ibiryo hamwe nababikamyo.
Mu bushyuhe bwo hejuru (hejuru ya 40 ℃): Irinde kongeramo HPMC kugeza ubushyuhe bwo hejuru. Birasabwa kujugunya mumazi akonje mbere yo gushyushya, cyangwa hitamo ubushyuhe bwo hejuru hpmc kugirango igabanye ingaruka zo gutahura ubushyuhe kuri porogaramu.
Ubushyuhe bufite ingaruka zikomeye kubakemuke, vinosity, pelation yubushyuhe hamwe nubushyuhe bwumuriro bwaHpmc. Mugihe cyo gusaba, birakenewe guhitamo icyitegererezo nuburyo bwo gukoresha HPMC ukurikije imiterere yubushyuhe bwihariye kugirango hamenyekane imikorere yacyo. Gusobanukirwa ubushyuhe bwa HPMC ntibishobora kunoza ireme ryibicuruzwa, ahubwo twirinde igihombo bitari ngombwa giterwa nubushyuhe no kunoza imikorere yubukungu nubukungu bwubukungu.
Igihe cya nyuma: Werurwe-28-2025