Nigute hyppimellose (hpmc) yakoreshejwe muburyo bwagutse-arekura tableti ya matrix?

Mu nganda za farumasi, hyppimellose (Hpmc, Uburyo bwo buryo bwo gukora Hypromellose yakoreshejwe mubinini birenga 60 kandi ni urufunguzo rwibanze rukoreshwa cyane mubinini bya Hydrophilic Gel Matrix.

Amasosiyete menshi ya farumasi akoresha Hypromellose kugirango arekurwe ibiyobyabwenge, cyane cyane muri Gel ya Gel Matrix. Ku bijyanye n'ibicuruzwa bya Hyppimellose, urashobora kwibaza uburyo wahitamo - cyane cyane niba ushaka ikintu cyangizaga urugwiro kandi kirambye ku isoko yawe. Muri iki gitabo, tuzavuga kubintu byingenzi ukeneye kumenya kuri HyPromellose.

HyPromellose ni iki?

Hypromellose, izwi kandi nkaHydroxyPropyl Methylcellse (HPMC), Ese polymer ikoreshwa nka farumasi yo kugenzura irekurwa ryibiyobyabwenge mubinini bya hydrophilic Gel Matrix.

Hypromellose nibikoresho bya kimwe cya kabiri gikomoka kuri selile, polymer myinshi muri kamere. Bimwe mubintu bisanzwe birimo:

. gushonga mumazi akonje

. SHAKA AMAZI ASHYIRA

. Nonic

. Guhitamo gukemurwa mubintu byiza

. Kumenyekana, Umubumbe wa Gel

. Hydration na vicosity bigenga PH

. Kubaga

. Uburozi

. Uburyohe n'umunuko byoroheje

. Enzyme Kurwanya

. ph (2-13) gushikama

. Irashobora gukoreshwa nka Thickener, Emulsifuer, Bunder, Umuguzi Ushinzwe kugenzura, uwambere

Dydrophilic Gel Matrix tablet?

Hydrophilic Gel Matrix tablet nuburyo dosiye ishobora kugenzura ibiyobyabwenge bivuye kuri tablet mugihe kirekire.

Hydrophilic Gel Preat Tablet Imyiteguro:

. Bidasanzwe

. Bisaba ibikoresho bya tablet bisanzwe

. Irinde ibiyobyabwenge bijugunywa

. Ntabwo bigira ingaruka kubinini bya tablet cyangwa imbaraga zo kwikuramo

. Kurekura ibiyobyabwenge birashobora guhindurwa ukurikije umubare wababyabaye na polymers

Imikoreshereze ya Hypromellose mubibi bya Gel-Matrix byakiriye ibyemezo byinshi byemejwe kandi bifite ibyanditswe byiza byumutekano, bigaragazwa nubushakashatsi bwinshi. Hypromellose yabaye amahitamo meza kubigo bya farumasi kwiteza imbere no gutanga ibisate byarakaye.

Ibintu bireba kurekura ibiyobyabwenge kuva tableti ya Matrix:

Iyo ushushanyijeho igisate cyagutse, hari ibintu bibiri by'ingenzi ugomba gusuzuma: gushyiraho no gutunganya. Hariho kandi ibintu bitarimo ibintu kugirango dusuzume mugihe ugena imiterere no kurekura umwirondoro wibicuruzwa byanyuma.

Formula:

Ibintu by'ingenzi tugomba gusuzuma iterambere hakiri kare:

1. Polymer (ubwoko bwo gusimbuza, viscosity, umubare no kumeneka)

2. Ibiyobyabwenge (ingano yinshi hamwe no kwikuramo)

3. Abakozi bongeraho (kukecururizwa no gutanga dosiye)

4. Abandi bababaye (stabilizers na buffers)

Ubukorikori:

Izi ngingo zifitanye isano nuburyo ibiyobyabwenge byakozwe:

1.. Uburyo bwo gutanga umusaruro

2. Ingano ya tablet

3. Imbaraga za Tablet

4. Ibidukikije

5.

Uburyo Chops ya Skeleton Akazi:

Ibinini bya Hydrophilic Gel Matrix birashobora kugenzura irekurwa ryibiyobyabwenge binyuze muri gel igice, harimo uburyo bubiri bwo gukwirakwiza) hamwe nisuno ikora (gusa ibikorwa bya polymer bifite uruhare runini kurugamba rwo kurekura. Gukoresha Hyppromellose, amasosiyete ya farumasi arashobora gukoresha tekinoroji ya Gel Matrix kugirango ahindure umwirondoro wibiyobyabwenge, gutanga dosiye nziza kandi bigabanya umutwaro wimiti ku barwayi. Uburyo bwo gufata imiti rimwe kumunsi birumvikana kuruta uburambe bwo gufata ibinini byinshi inshuro nyinshi kumunsi.