Nigute ushobora kugera kuri viscosity nziza ya HPMC mumyenda yo kumesa

(1) Intangiriro kuri HPMC
Hydroxypropyl Methylcellulose (HPMC) ni selile yingenzi ya selilose ether ikoreshwa cyane mumashanyarazi, ibikoresho byubaka, ibiryo, ubuvuzi nizindi nzego. Imyenda yo kumesa, HPMC ikoreshwa nkibyimbye kugirango itange ihagarikwa ryiza kandi ihindagurika, byongera imbaraga zo gukaraba no gukaraba. Ariko, kugirango ugere ku bwiza bwa HPMC mu kumesa, ibintu byinshi bigomba kwitabwaho, harimo ubwoko, dosiye, imiterere yo gusesa, uko byakurikiranye, nibindi bya HPMC.

(2) Ibintu bigira ingaruka kuri HPMC
1. Ubwoko nicyitegererezo cya HPMC
Uburemere bwa molekuline hamwe nintera yo gusimburwa (mikorerexy na hydroxypropyl isimburwa) ya HPMC bigira ingaruka kuburyo butaziguye nubwiza bwabyo. Ubwoko butandukanye bwa HPMC bufite ubunini butandukanye. Guhitamo icyitegererezo cya HPMC gikwiranye no kumesa ibikoresho byo kumesa ni ngombwa. Muri rusange, uburemere buke bwa molekile HPMCs itanga ububobere buke, mugihe uburemere buke bwa molekile HPMCs butanga ububobere buke.

2. Umubare wa HPMC
Ingano ya HPMC igira ingaruka zikomeye kubwiza. Mubisanzwe, HPMC yongerwaho muburyo buri hagati ya 0.5% na 2% mumyenda yo kumesa. Igipimo kiri hasi cyane ntikizagera ku ngaruka zifuzwa, mugihe dosiye iri hejuru cyane ishobora gukurura ibibazo nkikibazo cyo gusesa no kuvanga kutaringaniye. Kubwibyo, ibipimo bya HPMC bigomba guhinduka ukurikije ibikenewe byihariye nibisubizo byubushakashatsi kugirango bigere ku bwiza.

3. Ibihe byo guseswa
Imiterere yo gusesa ya HPMC (ubushyuhe, agaciro ka pH, umuvuduko ukabije, nibindi) bigira ingaruka zikomeye kubwiza bwayo:

Ubushyuhe: HPMC ishonga gahoro gahoro kubushyuhe bwo hasi ariko irashobora gutanga ububobere buke. Irashonga vuba mubushyuhe bwinshi ariko ifite ubukonje buke. Birasabwa gusesa HPMC hagati ya 20-40 ° C kugirango hamenyekane neza kandi neza.

pH: HPMC ikora neza mubihe bidafite aho bibogamiye. Indangagaciro za pH zikabije (acide cyane cyangwa alkaline cyane) irashobora gusenya imiterere ya HPMC no kugabanya ububobere bwayo. Kubwibyo, kugenzura pH agaciro ka sisitemu yo kumesa hagati ya 6-8 bifasha kugumana ituze hamwe nubwiza bwa HPMC.

Umuvuduko ukurura: Umuvuduko ukwiye urashobora gukurura HPMC, ariko gukurura cyane birashobora kuzana ibibyimba kandi bikagira ingaruka kumuti umwe. Mubisanzwe birasabwa gukoresha umuvuduko utinda ndetse ukurura umuvuduko kugirango ushonga HPMC.

4. Ongeraho gahunda
HPMC byoroshye gukora agglomerates mugisubizo, bigira ingaruka kumiseswa yayo no gukora neza. Kubwibyo, gahunda HPMC yongeweho irakomeye:

Mbere yo kuvanga: Vanga HPMC nandi mafu yumye neza hanyuma ubyongere buhoro buhoro mumazi, bishobora kubuza kwibumbira hamwe no gufasha gushonga neza.

Kuvomera: Mbere yo kongeramo HPMC kumuti wo kumesa, urashobora kubanza kuyivanga n'amazi make akonje, hanyuma ukongeramo amazi ashyushye kugirango uyashonge. Ibi birashobora kunoza imikorere yo gusesa hamwe nubwiza bwa HPMC.

(3) Intambwe zo kunoza ubwiza bwa HPMC
1. Igishushanyo mbonera
Hitamo icyitegererezo cya HPMC hamwe na dosiye ukurikije imikoreshereze yanyuma nibisabwa byo kumesa. Ibikoresho byoza neza cyane byo kumesa birashobora gusaba HPMC yuzuye cyane, mugihe ibicuruzwa rusange byogusukura bishobora guhitamo hagati ya HPMC.

2. Kugerageza
Kora ibizamini bito muri laboratoire kugirango urebe ingaruka zabyo ku bwiza bwimyenda yo kumesa uhindura dosiye, imiterere yo gusesa, gahunda yo kongeramo, nibindi bya HPMC. Andika ibipimo nibisubizo bya buri igerageza kugirango umenye guhuza neza.

3. Guhindura inzira
Koresha uburyo bwiza bwa laboratoire hamwe nuburyo bwo gutunganya kumurongo wibyakozwe hanyuma ubihindure kubyara umusaruro munini. Menya neza gukwirakwiza no gusesa HPMC mugihe cyumusaruro kugirango wirinde ibibazo nkibisebe no gusesa nabi.

4. Kugenzura ubuziranenge
Binyuze muburyo bwo gupima ubuziranenge, nko gupima viscometer, gupima ingano yubunini, nibindi, imikorere ya HPMC mumyenda yo kumesa irakurikiranwa kugirango igere kuntego ziteganijwe no gukoresha ingaruka. Kora ubugenzuzi busanzwe kandi uhite uhindura inzira na formula niba ibibazo bibonetse.

(4) Ibibazo bikunze kubazwa nibisubizo
1. Gusenya nabi HPMC
Impamvu: Ubushyuhe budakwiye bwo gusesa, byihuse cyane cyangwa buhoro buhoro umuvuduko ukabije, gahunda yo kongeramo idakwiye, nibindi.
Igisubizo: Hindura ubushyuhe bwo gushonga kuri 20-40 ° C, koresha umuvuduko utinze ndetse ukurura umuvuduko, hanyuma uhindure urutonde rwiyongera.
2. Ubukonje bwa HPMC ntabwo buri hejuru
Impamvu: Moderi ya HPMC ntikwiye, dosiye ntabwo ihagije, agaciro ka pH ni hejuru cyane cyangwa kari hasi cyane, nibindi.
Igisubizo: Hitamo icyitegererezo cya HPMC na dosiye, hanyuma ugenzure pH agaciro ka sisitemu yo kumesa hagati ya 6-8.
3. Imiterere ya HPMC
Impamvu: HPMC yongewemo muburyo butaziguye, ibisubizo bidakwiye, nibindi.
Igisubizo: Koresha uburyo bwabanje kuvanga, banza uvange HPMC nandi mafu yumye, hanyuma ubyongere buhoro buhoro mumazi kugirango bishonge.

Kugirango ugere ku bwiza bwa HPMC mu kumesa, ibintu nkubwoko, dosiye, imiterere yiseswa, hamwe nuburyo bwo kongeramo HPMC bigomba gutekerezwa byimazeyo. Binyuze mu bishushanyo mbonera bya siyansi, kugerageza ubushakashatsi no guhindura imikorere, imikorere ya viscosity ya HPMC irashobora kunozwa neza, bityo bikazamura ingaruka zo gukoresha no guhatanira isoko kumyenda yo kumesa.


Igihe cyo kohereza: Nyakanga-08-2024