Ongerahohydroxypropyl methylcellulose (HPMC)kumashanyarazi isaba intambwe nubuhanga bwihariye kugirango irebe ko ishobora gushonga kandi ikagira uruhare mukubyimba, gutuza no kunoza imvugo.
1. Ibiranga shingiro nibikorwa bya HPMC
Ibiranga HPMC
HPMC ni selile idafite ionic ether hamwe no gukemuka neza, kubyimba no gutuza. Irashobora gukora igisubizo kibonerana muri sisitemu yo mumazi kandi ikagira ihinduka rikomeye ryimihindagurikire yubushyuhe na pH.
Uruhare mumashanyarazi
Ingaruka yibyibushye: Tanga ubukonje bukwiye kandi utezimbere ibyiyumvo.
Iterambere rihamye: Irinde ibyuka cyangwa imvura.
Guhindura imvugo: Tanga ibintu byamazi meza kandi afite ubushobozi bwo guhagarika.
Kunoza ubunararibonye bwabakoresha: Kongera ituze hamwe no gufatira ifuro.
2. Intambwe zifatizo zo kongera HPMC
Kwitegura
Guhitamo: Hitamo icyitegererezo cya HPMC (nk'icyiciro cya viscosity, urwego rwo gusimbuza, nibindi) ukurikije ibicuruzwa bisabwa. Moderi isanzwe irimo ubukonje buke hamwe nubwiza bwinshi HPMC kubintu bitandukanye byo kubyimba.
Gupima: Gupima neza HPMC isabwa ukurikije formulaire.
Mbere yo gukwirakwiza HPMC
Guhitamo itangazamakuru: Mbere yo gukwirakwiza HPMC n'amazi akonje cyangwa ibindi bitangazamakuru bidashonga (nka Ethanol) kugirango wirinde kwibibyimba iyo byongeweho bitaziguye.
Uburyo bwo kongeramo: Kunyunyuza buhoro HPMC mumazi akonje kugirango wirinde guhuriza hamwe.
Inzira yo gukurura: Komeza kubyutsa iminota igera ku 10-15 kugeza igihe habaye gutandukana.
Intambwe zo gusesa
Gushyushya ibikorwa: Shyushya ikwirakwizwa kuri 40-70 ℃ kugirango uteze kubyimba no gusenyuka kwa HPMC. Twabibutsa ko ubushyuhe bwo gusesa HPMC yuburyo butandukanye buratandukanye gato.
Kuzunguruka no gushonga: Mugihe ushyushye, komeza ubyuke mumuvuduko uringaniye kugeza HPMC yasheshwe burundu kugirango ibe amazi yera yera cyangwa amata.
Kuvanga namazi yo kwisiga yibanze
Ubuvuzi bukonje: Cool theHPMCigisubizo cyubushyuhe bwicyumba kugirango wirinde ingaruka zubushyuhe bukabije kubindi bikoresho bikora.
Buhoro buhoro wongeyeho: Ongeraho buhoro buhoro igisubizo cya HPMC mumazi yo kwisukamo amazi mugihe ukangura kugirango ugabanye kimwe.
Guhindura Viscosity: Hindura ingano yumuti wa HPMC kugirango ugere kubwiza bwifuzwa.
3. Kwirinda
Irinde guhuriza hamwe
Iyo wongeyeho HPMC, uyisukeho buhoro hanyuma ubyuke neza, bitabaye ibyo biroroshye gukora agglomerates, bikavamo gusenyuka kutuzuye.
Mbere yo gutatanya nintambwe yingenzi, kandi gukoresha amazi akonje cyangwa ibindi bitangazamakuru bidashobora gukemura birashobora gukumira neza agglomeration.
Uburyo bukangura
Koresha umuvuduko ukabije kugirango wirinde ibibyimba biterwa no gukurura byihuse, bizagira ingaruka kumiterere yimiterere yimyanda.
Niba bishoboka, koresha ibikoresho-bikurura ibikoresho kugirango utezimbere neza.
Kugenzura ubushyuhe
HPMC yunvikana n'ubushyuhe, kandi hejuru cyane cyangwa ubushyuhe buke burashobora gutera gusesa nabi cyangwa gutakaza ibikorwa. Kubwibyo, ubushyuhe bugomba kugenzurwa cyane mugihe cyo gusesa.
Guhuza nibindi bikoresho
Reba ubwuzuzanye bwa HPMC hamwe nibindi bikoresho byogejwe, cyane cyane ibidukikije byumunyu mwinshi bishobora kugira ingaruka kubyimbye bya HPMC.
Kumashanyarazi arimo aside irike cyangwa alkalis ikomeye, hagomba kubaho umutekano wa HPMC.
Igihe cyo guseswa
Bifata igihe runaka kugirango HPMC isenyuke burundu, kandi igomba gukangurwa wihanganye kugirango wirinde guhungabana kwijimye kubera guseswa kutuzuye.
4. Ibibazo rusange nibisubizo
Ingorane zo guseswa
Impamvu: HPMC irashobora guhurizwa hamwe cyangwa ubushyuhe bwo gusesa ntibikwiye.
Igisubizo: Hindura intambwe ibanziriza gutatanya kandi ugenzure neza uburyo bwo gushyushya no gukurura.
Gutandukanya ibice cyangwa imvura
Impamvu: Kwiyongera kwa HPMC bidahagije cyangwa guseswa kutuzuye.
Igisubizo: Ongera umubare wa HPMC uko bikwiye kandi urebe ko iseswa ryuzuye.
Ubukonje bukabije
Impamvu: HPMC cyane yongeyeho cyangwa ivanze kimwe.
Igisubizo: Mugabanye neza umubare wongeyeho kandi wongere igihe cyo gukurura.
OngerahoHPMCkumashanyarazi yamazi ninzira isaba kugenzura neza. Kuva muguhitamo icyitegererezo cya HPMC kugirango uhindure iseswa no kuvanga intambwe, buri ntambwe igira ingaruka zikomeye kumikorere yibicuruzwa byanyuma. Binyuze mu mikorere ikwiye, ibikorwa byo kongera umubyimba, gutuza no kuvugurura imvugo ya HPMC birashobora gukoreshwa neza, bityo bikazamura imikorere no guhatanira isoko kumashanyarazi.
Igihe cyo kohereza: Ukuboza-10-2024