HPMC (HydroxyPropyl Methylcellse) ni umubyimba kandi stabilizeri ikoreshwa mubikoresho byubaka, amababi, imiti nibiryo. HPMC 15 CP bivuze ko virusi yayo ari santiso 15, nicyiciro gito cya virusi.
1. Ongera kwibanda kuri HPMC
Nuburyo butaziguye kandi bujuje neza bwo kongera viscosity ya HPMC nukwongera kwibanda kubisubizo. Iyo igipadiri rusange cya HPMC cyiyongera, viscogity yigisubizo nayo iziyongera. Intangiriro yubu buryo nuko HPMC yongerera visositity igisubizo mugukora imiterere yinkubo eshatu. Nkumubare wa molekile ya HPMC mubisubizo byiyongera, ubucucike n'imbaraga zurwego rwurusobe narwo ruziyongera, bityo twongera victoity yumuti. Ariko, hariho imipaka yo kongera kwibanda. Byinshi cyane kwibanda kuri HPMC bizatera amazi yumuti wo kugabanuka, kandi ushobora no kugira ingaruka kubikorwa byayo muburyo bwihariye, nko kubaka no gufatana.
2. Igenzura ubushyuhe bwigisubizo
Ubushyuhe bufite uruhare runini ku kuntu kwikebana no gusya ya HPMC. Ku bushyuhe bwo hasi, viscosiya igisubizo cya HPMC kiri hejuru; Mugihe hejuru yubushyuhe bwinshi, viscosiya igisubizo cya HPMC kizagabanuka. Kubwibyo, kugabanya ubushyuhe bwigisubizo neza mugihe cyo gukoresha birashobora kongera vicosity ya HPMC. Twabibutsa ko gukemurwa kwa HPMC mubisubizo bitandukanye mubushyuhe butandukanye. Mubisanzwe byoroshye gutatanya mumazi akonje, ariko bisaba igihe runaka kugirango ushonge. Birashonga byihuse mumazi ashyushye, ariko viscosity iri hasi.
3. Hindura PH agaciro ka Solven
Uruzinduko rwa HPMC narwo rutumva agaciro PH agaciro k'igisubizo. Mubihe bitabogamye cyangwa hafi-kutabogama, viscosiya igisubizo cya HPMC nicyo kinini. Niba agaciro ka PH gatangwamo kutabogama, viscosity irashobora kugabanuka. Kubwibyo, viscosiyani yo gukemura HPMC irashobora kwiyongera no guhindura neza agaciro ka PH agaciro (kurugero, wongeyeho buffer cyangwa aside-shingiro ya acide). Ariko, muburyo bufatika, guhindura agaciro rya PH bigomba kwitonda cyane, kuko impinduka nini zishobora gutera ppmc gutesha agaciro hpmc cyangwa gutesha agaciro.
4. Hitamo umuti ukwiye
Kudakemu no guscosity ya HPMC muri sisitemu zitandukanye za sisitemu ziratandukanye. Nubwo HPMC ikoreshwa cyane cyane mubisubizo bitangaje, hiyongereyeho ibiti bimwe na bimwe byamagana (nka ethanol, isopropanol, nibindi bitandukanye birashobora guhindura urunigi rwimiti ya HPMC, bityo akagira ingaruka kuri vilecule. Kurugero, umubare muto wibinyabuzima kama birashobora kugabanya kwivanga muri molekile yamazi kuri HPMC, bityo yongera viscosiya. Mubikorwa byihariye, birakenewe guhitamo ibicuruzwa bikwiye ukurikije porogaramu nyayo.
5. Koresha imfashanyo
Rimwe na rimwe, izindi mfashanyo zijimye zirashobora kongerwaho kuri HPMC kugirango igere ku ngaruka zo kongera viscosiya. Bikunze gukoreshwa sidaning ifasha Xanthan gum, gum, Carbomer, nibindi. Kurugero, Xanthan gum numusingi karemano ufite ingaruka zikomeye. Iyo ikoreshwa hamwe na HPMC, bombi barashobora gukora ingaruka zubushakashatsi kandi bongera cyane viscosity ya sisitemu.
6. Hindura impamyabumenyi yo gusimbuza HPMC
Uruzinduko rwa HPMC narwo rufitanye isano no kusimbuza uburyo bwabwo na hydroxyPropoplexy. Urwego rwo gusimburwa rugira ingaruka ku kuntu kwikeba no kureba igisubizo. Muguhitamo HPMC hamwe na dogere zitandukanye zo gusimburwa, viscolity yumuti irashobora guhinduka. Niba virusiki yo hejuru HPMC irakenewe, ibicuruzwa bifite uburyo bwo hejuru burashobora gutoranywa, kuko urwego rwo hejuru, rukomeye rwa hpmc ya HPMC, kandi ni urujijo nyuma yo gusesa.
7. IGIHE CY'IGIHE CY'ISI
Igihe cya HPMC ishonga nabyo bizagira ingaruka ku rubyiruko rwayo. Niba HPMC idasenyutse rwose, viscolity yumuti ntizishobora kugera kuri leta nziza. Kubwibyo, kwagura neza igihe cya HPMC mumazi kugirango umenye ko HPMC ifite hydd rwose irashobora kongera ubukwe bwikibazo cyayo. Cyane cyane iyo gushonga mubushyuhe buke, inzira yo gusebanya ya HPMC irashobora gutinda, kandi kongereye igihe ni ngombwa.
8. Hindura imiterere
Uruzinduko rwa HPMC narwo rufitanye isano no gukorerwa imbaraga zikorerwa mu gihe cyo gukoreshwa. Mu bihe byinshi, uruzinduko rw'igisubizo cya HPMC ruzagabanuka by'agateganyo, ariko iyo imiduka ihagarara, uruzitiro ruzakira. Kubitunganya bisaba ubuyobe bwiyongera, imbaraga zububasha igisubizo cyatanzwe gishobora kugabanywa, cyangwa gishobora gukorerwa munsi yubusa kugirango ukomeze ubushishozi bwo hejuru.
9. Hitamo uburemere bwiburyo bwa molecular
Uburemere bwa moleki ya HPMC bugira ingaruka kuburyo butaziguye. HPMC hamwe nuburemere bunini bwa molecular ikora imiterere minini yo mu gisubizo, bikavamo ubushishozi bwo hejuru. Niba ukeneye kongera ubukwe bwa HPMC, urashobora guhitamo ibicuruzwa bya HPMC bifite uburemere bwinzira nyabagendwa. Nubwo HPMC 15 CPS nigicuruzwa gito cya stcosity, viscosiya irashobora kwiyongera muguhitamo igice kinini-uburemere butandukanye bwibicuruzwa bimwe.
10. Reba ibintu bidukikije
Ibintu byibidukikije nkubushuhe nigitutu birashobora kandi kugira ingaruka runaka kuri viscosity yo gukemura Hpmc. Mu bushyuhe buhebuje, HPMC irashobora gukurura ubuhehere mu kirere, bigatuma habaho ubuyobe. Kugira ngo wirinde ibi, imiterere y'ibidukikije yo gutanga umusaruro cyangwa urubuga irashobora kugenzurwa neza kugirango ibidukikije byumuke kandi igitutu gikwiye kugirango ukomeze viscolity igisubizo cyigisubizo cya HPMC.
Hariho inzira nyinshi zo kongera viscosity ya HPMC 15 CPS, harimo no kwibanda, guhindura ubushyuhe, gukoresha imfashanyo Ibisabwa na gahunda. Mubikorwa nyabyo, akenshi birakenewe kubyumva ibintu byinshi no kugira ibyo uhindura no guhitamo kugirango imikorere myiza yigisubizo cyihariye.
Igihe cya nyuma: Ukwakira-16-2024