HPMC yo gukinisha film

HydroxyPropyl Methyl Cellulose (HPMC) ikoreshwa mu nganda za farumasi nkabashimishwa muri film. Guhimba firime ni inzira aho urwego ruto, rukoreshwa na polymer rukoreshwa muburyo bukomeye bwo gutanga dosiye, nkibinini cyangwa capsules. HPMC itanga inyungu zitandukanye muri porogaramu zo gukwirakwiza film, harimo gushiraho firime, kuroga, no kugenzurwa aharemurwa. Dore incamake ya porogaramu, imikorere, hamwe nibitekerezo bya HPMC muri firime:

1. Kumenyekanisha HydroxyPropyl Methyl Cellulose (HPMC) muri firime

1.1 Uruhare muri firime

HPMC ikoreshwa nkumukozi wa firime muri firime ya farumasi yo guhimba. Itanga igikona neza kandi kimwe hejuru yimpapuro zikomeye, zigira uruhare mubikorwa byabo, ituze, no koroshya kumira.

1.2 Inyungu muri Porogaramu yo gukwirakwiza film

• Gushiraho filime: HPMC ikora firime yoroshye kandi ibonerana iyo ikoreshwa hejuru yibinini cyangwa capsules, gutanga uburinzi no kuzamura astethestics.
• Adhesion: HPMC yongera ubumwe, kwemeza ko film ikurikiza kimwe kuri substrateur kugeza substrate kandi ntabwo ihagarika cyangwa ngo ikure cyangwa ishishikarire.
• Kugenzurwa: Ukurikije urwego rwihariye rwakoreshejwe, HPMC irashobora gutanga umusanzu mu kurekura farumasi ikora ya farumasi ikora (api) kuva kumurongo wa dosiye.

2. Imikorere ya HydroxyPropyl Methyl Cellulose muri Film

2.1 gushiraho firime

HPMC ikora nkumukozi ushinzwe film, akora firime yoroheje kandi imwe hejuru yibinini cyangwa capsules. Iyi filime itanga uburinzi, masike uburyohe cyangwa impumuro yibiyobyabwenge, kandi itezimbere isura rusange.

2.2

HPMC yongera ubumwe hagati ya firime na substrate, ireza ishyaka rihamye kandi rirambye. Guhisha bikwiye birinda ibibazo nko kuvuza cyangwa gukuramo mugihe cyo kubika cyangwa gufata.

2.3 Kugenzurwa

Impamyabumenyi zimwe za HPMC zagenewe gutanga umusanzu mu kugengwa-Kurekura imitungo, bigira ingaruka ku gipimo cyo kurekura igice gikora mu buryo bw'igifu. Ibi ni ngombwa cyane cyane kurekura cyangwa kurekura-kurekura.

2.4 Iterambere ryiza

Gukoresha HPMC muri firime yo gutwikira birashobora guteza imbere ubujurire bugaragara bwuburyo bwa dosage, bigatuma biremewe kubarwayi. Filime itanga kurangiza neza kandi glossy.

3. Gusaba muri firime

3.1 Ibinini

HPMC ikunze gukoreshwa mubisate bya firime, itanga urwego rurinda no kuzamura isura yabo. Birakwiriye kubitera tablet itandukanye, harimo kurekurwa no gusohora kandi bigurwa-birekura ibicuruzwa.

3.2 capsules

Usibye ibinini, HPMC ikoreshwa mu guhinga kapsules, ikagira uruhare mu gutuza kwabo no gutanga isura imwe. Ibi ni ngombwa cyane kubwiryoshe- cyangwa impumuro nziza.

3.3 uburyohe

HPMC irashobora gukoreshwa guhisha uburyohe cyangwa impumuro ikora ibintu byingenzi byimiti, kunoza uburenganzira bwo kwiyemera, cyane cyane muri pediatric cyangwa imirire yabaturage.

3.4 Kugenzurwa-Kurekura

Kubigenzurwa-kurekurwa cyangwa gusohora ibintu, HPMC igira uruhare runini mu kugera kumwirondoro wifuza, yemerera kurekurwa ibiyobyabwenge byagenwe kandi bigenzurwa kandi bigenzurwa kandi bigenzurwa no kugenzurwa mu gihe.

4. ICYIBERE

4.1 Guhitamo icyiciro

Guhitamo icyiciro cya HPMC bigomba gushingira ku bisabwa byihariye byo gusaba film Porogaramu, harimo imitungo ya filime yifuzwa, kumesa, no kugenzurwa-kurekura.

4.2 Guhuza

Guhuza nabandi bababaye hamwe nibikorwa bikora bya farumasi ni ngombwa kugirango harebwe umutekano no gukora urupapuro rwabigenewe.

4.3 film

Ubunini bwa firime bugomba kugenzurwa neza kugirango bubone ibisabwa na gahunda no kwirinda ibibazo nko kwirengana, bishobora kugira ingaruka kubisigara kandi bibaho.

5. UMWANZURO

HydroxyPropyl Methyl Cellulose ni umuntu wingenzi muri film ya farumasi yo guhinga porogaramu, itanga film ya farumasi, itanga filime, kuroga, no kugenzurwa-kurekura. Impapuro zipimbano za firime zitanga icyerekezo cyiza, kurinda, no kwihangana kwemerwa. Gusuzuma neza icyiciro, guhuza, no kuri firime birakenewe kugirango ukoreshe HPMC neza muri firime zitandukanye.