Hydroxypropyl methyl selulose na sodium ya carboxymethyl selulose irashobora kuvangwa

Hydroxypropyl methyl selulose (HPMC) na sodium ya carboxymethyl selulose (CMC) ni bibiri bikoreshwa cyane muri selile mu nganda zitandukanye bitewe n'imiterere yihariye n'imikorere. Mugihe byombi ari selile-ishingiye kuri polymers, ziratandukanye mumiterere yimiti nimiterere yabyo, bigatuma bikenerwa mubikorwa bitandukanye. Ariko, mubihe bimwe na bimwe, birashobora kuvangwa kugirango bigere kumikorere yihariye cyangwa kuzamura imitungo runaka yibicuruzwa byanyuma.

Hydroxypropyl methyl selulose (HPMC), izwi kandi nka hypromellose, ni ether itari ionic selulose ether ikomoka kuri polymer naturel selile. Ihindurwamo binyuze muri reaction ya alkali selulose hamwe na oxyde ya propylene na methyl chloride. HPMC ikoreshwa cyane muri farumasi, ibikoresho byubwubatsi, ibiribwa, no kwisiga kubera uburyo bwiza bwo gukora firime, kubyimba, guhambira, no kubika amazi. HPMC iraboneka mubyiciro bitandukanye hamwe nuburyo butandukanye bwijimye, butuma ikoreshwa muburyo butandukanye bwa porogaramu.

Ku rundi ruhande, sodium ya carboxymethyl selulose (CMC) ni inkomoko y'amazi ya anionic selulose ikomoka ku reaction ya selile hamwe na hydroxide ya sodium na acide chloroacetic. CMC izwiho ubushobozi bwo gufata amazi menshi, ubushobozi bwo kubyimba, imiterere yo gukora firime, hamwe no guhagarara neza muburyo butandukanye bwa pH. Irasanga porogaramu mubiribwa, imiti, amavuta yo kwisiga, imyenda, no gukora impapuro bitewe nuburyo bwinshi ndetse na biocompatibilité.

Mugihe HPMC na CMC basangiye ibintu bimwe na bimwe nkibishobora gukemuka mumazi hamwe nubushobozi bwo gukora firime, barerekana kandi imiterere itandukanye ituma bikenerwa mubikorwa byihariye. Kurugero, HPMC ihitamo muburyo bwa farumasi nka tableti na capsules bitewe nuburyo bugenzurwa-kurekura no guhuza nibikoresho bikora imiti. Kurundi ruhande, CMC ikoreshwa mubicuruzwa byibiribwa nka sosi, imyambarire, nibicuruzwa bitetse nkibikoresho byongera umubyimba.

Nubwo batandukanye, HPMC na CMC barashobora kuvangwa hamwe muburyo bumwe kugirango bagere ku ngaruka zoguhuza cyangwa kuzamura imitungo yihariye. Ubwuzuzanye bwa HPMC na CMC biterwa nibintu byinshi nkimiterere yimiti yabyo, uburemere bwa molekile, urwego rwo gusimburwa, nibintu byifuzwa byibicuruzwa byanyuma. Iyo bivanze hamwe, HPMC na CMC birashobora kwerekana uburyo bwiza bwo kubyimba, guhuza, no gukora firime ugereranije no gukoresha polymer wenyine.

Uburyo bumwe busanzwe bwo kuvanga HPMC na CMC ni mugutegura uburyo bwo gutanga ibiyobyabwenge bishingiye kuri hydrogel. Hydrogels ni urwego rwibice bitatu byurusobekerane rushobora gukurura no kugumana amazi menshi, bigatuma bikoreshwa mugusohora ibiyobyabwenge bigenzurwa. Muguhuza HPMC na CMC mubipimo bikwiye, abashakashatsi barashobora guhuza imiterere ya hydrogel nkimyitwarire yo kubyimba, imbaraga za mashini, hamwe nibiyobyabwenge byo kurekura kugirango byuzuze ibisabwa byihariye.

Ubundi buryo bwo kuvanga HPMC na CMC ni mugutegura amarangi ashingiye kumazi. HPMC na CMC bikoreshwa cyane mubyimbye hamwe na rheologiya ihindura amarangi ashingiye kumazi kugirango banoze imikoreshereze yabyo, nko gukaraba, kurwanya sag, no kurwanya spatter. Muguhindura igipimo cya HPMC na CMC, abayikora barashobora kugera kubwiza bwifuzwa hamwe nimyitwarire yimyenda irangi mugihe bakomeje guhagarara neza no gukora mugihe runaka.

Usibye imiti n’imyenda, imvange ya HPMC na CMC inakoreshwa mu nganda z’ibiribwa kugira ngo hazamurwe imiterere, ituze, ndetse n’umunwa w’ibicuruzwa bitandukanye by’ibiribwa. Kurugero, HPMC na CMC bakunze kongerwaho mubikomoka ku mata nka yogurt na ice cream nka stabilisateur kugirango birinde gutandukanya ibice no kunoza amavuta. Mu bicuruzwa bitetse, HPMC na CMC birashobora gukoreshwa nkibikoresho byogosha kugirango byongere imitunganyirize yimigati kandi byongere ubuzima bwigihe.

mugihe hydroxypropyl methyl selulose (HPMC) na sodium ya carboxymethyl selulose (CMC) nibintu bibiri bitandukanye biva muri selile bifite imitungo idasanzwe hamwe nibisabwa, birashobora kuvangwa hamwe muburyo bumwe kugirango bigerweho kugirango bigerweho cyangwa byongere imitungo yihariye. Ubwuzuzanye bwa HPMC na CMC biterwa nibintu bitandukanye nkimiterere yimiti yabyo, uburemere bwa molekile, nibintu byifuzwa byibicuruzwa byanyuma. Muguhitamo neza igipimo no guhuza HPMC na CMC, abayikora barashobora guhuza imiterere yabyo kugirango bahuze ibisabwa byihariye muri farumasi, imiti, ibicuruzwa, nibindi nganda.