HydroxyPropyl Methyl Cellulose nka farumasi

HydroxyPropyl Methyl Cellulose (HPMC)ni igitangaza cya farusile gikoreshwa cyane muburyo butandukanye bwibipimo kubera imitungo yihariye. Iyi selile ikomoka kuri selile ikomoka kuri selile, mubisanzwe polymer iboneka mubimera, kandi ihindurwa binyuze mubitekerezo bya shimi kugirango ubone ibiranga byifuzwa. Muri farumasi, HPMC ikora imirimo myinshi, harimo na Binder, abahoze ari film wahoze, Thickener, Stabilizer, na Agent-Long. Gusaba n'akamaro kayo gakomeye mu nganda z'umuti z'imiti mu buryo bwumvikana ko dusobanukirwa imitungo yayo, porogaramu, n'inyungu.

HPMC yo kwitonda na virusi itera stcosity bituma bihitamo neza kugenzura kurekura ibiyobyabwenge muburyo bukomeye bwo gutanga dosiye. Ikora matrix ya gel kuri hydtion, ishobora guhamagarwa kurekurwa ibiyobyabwenge kubera gukwirakwizwa binyuze mubice bya gel yabyimbye. Uruzinduko rwa Gel ruterwa nibintu nkuburemere bwa molecular, urwego rwo gusimbuza, no kwibanda kuri HPMC muri forelation. Muguhindura ibi bipimo, abahanga mu bahanga mu bya farumasi barashobora kudoda imyirondoro yo kurekura ibiyobyabwenge kugirango bigerweho ku myanya ya operans, nko kurekurwa byihuse, harakuweho, cyangwa kurekurwa.

HPMC ikoreshwa nka binder muri tablet foine kugirango utange ubumwe kandi itezimbere imbaraga zamashini. Nkumuyoboro, uteza imbere guhuza amakuru na granule mugihe cya tablet ya tablet, bikaviramo ibinini bifite ibiyobyabwenge bimwe nibiyobyabwenge. Byongeye kandi, imiterere ya firime ya HPMC ituma ikwiranye no gufunga ibinini, bikora intego zitandukanye nkuburyohe, kurinda ubuhehere, no gusohora ibiyobyabwenge.

Usibye impapuro zikomeye za dosiye, HPMC isanga gusaba muyindi miti ya farumasi, harimo ibisubizo by'amasako, gels, ibipimo by'ibitabo, kandi bigenzurwa-bigenzurwa. Mu bisubizo bya Ophthalmic, HPMC ikora nkumukozi woza urukwavu, atezimbere igihe cyo gutura hejuru yubuso bwa ocular no kuzamura ibiyobyabwenge. Muri gels yibanze, itanga uburyo bwo kugenzurwa, bigatuma porogaramu yoroshye kandi yongerewe uruhu rwibintu bifatika.

Hpmc-Basegral Porogaramu itanga sisitemu yoroshye kandi idatera ibiyobyabwenge kuri sisitemu cyangwa iperereza. Matrix polymer igenzura ibiyobyabwenge binyuze mu ruhu mugihe kinini, kubungabunga urwego rwibiyobyabwenge mumaraso mugihe cyo kugabanya ihindagurika. Ibi ni byiza cyane kubiyobyabwenge hamwe na Windows ifunganye cyangwa abasaba ubuyobozi buhoraho.

HPMC's biocompaTubisobanuro no kunyuranya bituma bikwirakwira mugukora ubupfura nkumukozi uhagarika cyangwa virusity. Mugenzurwa-arekura amashiname, Microspheresi cyangwa nanoparceicles irashobora gukubitwa molekile zikoreshwa mu gihe kinini, bityo bigatuma kurekura inshuro nyinshi no kunoza kubahiriza abarwayi.

HPMC yerekana imitungo ya Mucoakelies, bigatuma ingirakamaro mubikorwa byateguwe kubiyobyabwenge bya mucosal, nka firime ya Buccal hamwe na spray. Mugukurikiza hejuru ya Mucosal, HPMC yirukanye igihe cyo guturamo ibiyobyabwenge, yemerera kwinjiza ibiyobyabwenge na bioakwayiality.

HPMC muri rusange izwiho umutekano (Gras) ku nzego zishinzwe kugenzura no gucunga ibiyobyabwenge (FDA) (FDA), bigatuma bikwiranye no gukoresha muri farumasi igenewe kunywa abantu. Biodegradableless na kamere idafite uburozi barushaho kugira uruhare mu bujurire bwabwo nka farumasi.

HydroxyPropyl Methyl Cellulose (HPMC)ni imiti itandukanye ya farusile hamwe nibisabwa bitandukanye muburyo butandukanye bwo gutanga dosiye. Ibintu byayo byihariye, harimo no kwikunda, viscosiya, ubushobozi bwo gushinga filime, na bionompaget, bigira ikintu cyingenzi mubikorwa bigize ibiyobyabwenge bigamije kugera ku ntego zihariye za therapeutic. Mugihe ubushakashatsi bwa farumasi bukomeje guhinduka, HPMC ishobora kuguma mu rufatiro rwibanze mugutezimbere sisitemu yo gutanga ibiyobyabwenge.