Hydroxypropyl methylcellse itandukaniro ryicyitegererezo

HydroxyPropyl Methylcellse (HPMC)Ese uruganda rutandukanye rukoreshwa mu nganda zinyuranye, harimo imiti, ibiryo, kwisiga, no kubaka. Imitungo na Porogaramu biratandukanye bitewe n'imiterere yabyo, ishobora guhinduka kugirango ibone ibyo bakeneye.

Imiterere yimiti:

HPMC ni ukomoka kuri selile, polymer karemano iboneka mubimera.
Abasimbura rya HydroxyPropyl na Methyl bafatanye mumatsinda ya hydroxyl yumugongo wa selile.
Ikigereranyo cya aba basimbuye kigena imitungo ya HPMC, nko kwikecuru, pelation, hamwe nubushobozi bwa firime.

Impamyabumenyi (DS):

DS ivuga impuzandengo yitsinda ryasimbutse kuri glucose ishami rya selile.
Indangagaciro zisumba izindi ziterwa na hydrophilitity, kudusabana, nubushobozi bwa gelateri.
HS HS HS HSMC irahagaze neza kandi ifite ubuhanga bwiza bwo kurwanya ubushuhe, bigatuma habaho gusaba ibikoresho byubwubatsi.

Uburemere bwa molekile (mw):

Uburemere bwa molekili bugira ingaruka kuri viscosity, ubushobozi bwa firime, hamwe nubukanishi.
Uburemere bwo hejuru bwa HPMC busanzwe bufite ubunini bwa vino nyinshi hamwe nuburyo bwiza bwo gukora firime, bigatuma bikwiranye kugirango bikoreshwe muburyo burambye.
Imyambarire yo hasi ya moleclar irahitamo kubisabwa aho bigaragara ko visolution yo hepfo hamwe no guseswa byihuse, nko mumajyambere no kugikora.

Ingano y'inyuguti:

Ingano yinshi igira ingaruka ku ifu yumutungo, igipimo cyivumburwa, nubwisanzure mubitera.
Ingano nziza ya HPMC ikwirakwiza byoroshye mubisubizo byimibare, biganisha ku kwihuta no gushinga gel.
Ibice bya coarsor birashobora gutanga imitungo myiza mu ruvange rwumye ariko irashobora gusaba igihe kinini cyo kurya.

Ubushyuhe bwa gelale:

Ubushyuhe bwa Gelasiyo bivuga ubushyuhe aho hpmc ibisubizo byinjira bivuye kumuti kuri gel.
Urwego rwo gusimbuza hamwe nuburemere bwa molekile muri rusange biganisha ku bushyuhe bwo hasi.
Gusobanukirwa ubushyuhe bwa gelation ni ngombwa muguhuza sisitemu yo kugenzura ibiyobyabwenge no mu musaruro wa gels kugirango dusangire.

Ubushyuhe:

Umutekano mu bushyuhe ni ngombwa mubisabwa aho HPMC ikorerwa ubushyuhe mugihe cyo gutunganya cyangwa kubika.
HS HPMC yo hejuru ya HS irashobora kwerekana ituze ryisumbuye ryo hasi bitewe no kuba hari abasimbuye labolite nyinshi.
Ubuhanga bwo gusesengura ubushyuhe nka calorimetry itandukanye (DSC) na TheRogravimecccc (Tga) ikoreshwa mugusuzuma imiterere yubushyuhe.

Kudacogora no kubyimba:

Kudacogora no kubyimba biterwa na DS, uburemere bwa moleki, nubushyuhe.
Ibipimo byinshi bya DS na MoleCular bitandukana mubisanzwe bimurikana cyane no kubyimba mumazi.
Gusobanukirwa no kwikunda no kubyimba biranegura mugutegura sisitemu yo kugenzurwa na sisitemu yo gutanga ibiyobyabwenge kandi bigatera sydrogels kubisabwa bigometse.

Imiterere ya motheologiya:

Ibintu byimkumi nka virusi, imyitwarire yoroheje yoroheje, hamwe na vickoelastitique ni ngombwa muburyo butandukanye.
HpmcIbisubizo byerekana imyitwarire ya pseudoplastique, aho becozetity igabanuka hamwe no kongera umubare munini.
Imiterere y'amagambo ya HPMC igira ingaruka ku gahunda yayo mu nganda nk'ibiribwa nk'ibiri, kwisiga, na farumasi.

the differences between various models of HPMC stem from variations in chemical structure, substitution degree, molecular weight, particle size, gelation temperature, thermal properties, solubility, swelling behavior, and rheological properties. Gusobanukirwa itandukaniro ningirakamaro kugirango uhitemo ibice bitandukanye bya HPMC kubisabwa byihariye, kuva muri farumasi yibikoresho byubwubatsi.