Hpmc hydrophobic cyangwa hydrophilic?

HydroxyPropyl methylcellse (HPMC) ni polymer itandukanye hamwe na hydrophobic na hydrophilique na hydrophilique na hydrophilique, bigatuma idasanzwe muburyo butandukanye mubisabwa muburyo butandukanye. Kugirango dusobanukirwe hydrophobicique na hydrophilitity ya HPMC, dukeneye kwiga imiterere, imitungo na porogaramu yimbitse.

Imiterere ya HydroxyPropyl Methylcellse:

HPMC ni ukomoka kuri selile, polymer karemano iboneka murukuta rwa selile. Guhindura selile bikubiyemo gutangiza amatsinda ya hydroxy okarishwa na methyl muri selile. Iyi mpinduka ihindura imitungo ya polymer, itanga imitungo yihariye ingirakamaro kubisabwa muburyo butandukanye.

Hydrophilicity ya HPMC:

Hydroxy:

HPMC ikubiyemo amatsinda ya hydroxyPropyle kandi ni hydrophilic. Aya matsinda ya hydroxyl afite ubuhinzi burebure bwa molekile zamazi kubera amarira ya hydrogen.

Itsinda rya HydroxyPropyl rirashobora gukora hydrogen ingwate hamwe na molekile y'amazi, ikora HPMC ishonje mumazi kurwego runaka.

methyl:

Mugihe itsinda rya metyyl rigira uruhare muri hydrophobity muri rusange molekile, ntabwo irwanya hydrophile yamatsinda ya hydroxyProppoyle.

Itsinda rya methyl ritandukanye, ariko kuboneka kw'itsinda rya hydroxyPropyl rigena imiterere ya hydrophilique.

Hydrophobitity ya HPMC:

methyl:

Amatsinda ya Methyl muri HPMC agena urugero rwa hydrophobity.

Nubwo atari hydrophobic nka bamwe muburyo bwuzuye syntheptic, kuba hari amatsinda ya methyl bigabanya hydhifilirize ya HPMC.

Filime ikora ibintu:

HPMC izwiho imitungo yo gukora firime kandi ikunze gukoreshwa muri pharmacetical kandi yo kwisiga. Hydrophomicique itanga umusanzu wa firime ikingira.

Imikoranire nibintu bitarimo polar:

Muri porogaramu zimwe, HPMC irashobora gukorana nibintu bidafite polar biterwa na hydrophobity yayo. Uyu mutungo ningirakamaro muri sisitemu yo gutanga ibiyobyabwenge mumitsi yimiti.

Gusaba HPMC:

Ibiyobyabwenge:

HPMC ikoreshwa cyane mubikorwa bya farumasi nka binder, firime yahoze, hamwe na vicosity. Ubushobozi bwayo bwa firime bworohereza kurekura ibiyobyabwenge.

Ikoreshwa muburyo bukomeye bwo gutanga dosiye nka tableti na capsules.

Inganda zubwubatsi:

Mu rwego rwo kubaka, HPMC ikoreshwa mu bicuruzwa bishingiye ku mikorere yo kunoza ibikorwa, kugumana amazi no kumeneka.

Hydrophility ifasha kugumana amazi, mugihe hydrophobicity ifasha kunoza ubushishozi.

Inganda zibiribwa:

HPMC ikoreshwa nkumuntu wijimye hamwe numukozi wa umwe munganda. Kamere yayo ya hydrophilic ifasha gukora gels ihamye no kugenzura vicosity yibiryo.

kwisiga:

Mu kwisiga, HPMC ikoreshwa mubicuruzwa nka cream hamwe namavuta kubera ibikoresho bya firime no kubyimba.

Hydrofilire iremeza amazi meza y'uruhu.

Mu gusoza:

Hpmc ni polymer iyo hydrophilic na hydrophobic. Amafaranga asigaye hagati ya hydroxyle na methyl mumiterere yacyo ayitanga urugero rwihariye, kubikesha kugira uruhare runini. Gusobanukirwa iyi mitungo ni ngombwa kugirango udoda hpmc muburyo bwihariye munganda butandukanye, aho ubushobozi bwa HPMC ikorana namazi nibikoresho bidakoreshwa muburyo butandukanye.