HydroxyPropylmethylcellcellCellCellse (HPMC) ni polymer itandukanye kandi itandukanye yumuryango wa alther. Nibisobanuro binyuze murukurikirane rwibisubizo bya shimi bigahindura selile karemano, igice cyingenzi cyinkuta zamababi. HPMC yavuyemo ifite imitungo idasanzwe ikora ifite agaciro munganda.
1. Imiterere yimiti nibigize:
HPMC ikomoka kuri selile, igizwe no gusubiramo ibice bya glucose bihujwe na β-1,4-glycosic. Binyuze mu guhindura imiti, hydroxyPropyl na memoxy byitangizwa mu mukongo wa selile. Urwego rwo gusimbuza (DS) rwa HydroxyPropyl na Methoxy office irashobora gutandukana, bikaviramo amanota atandukanye ya HPMC ifite ibintu bitandukanye.
Imiterere yimiti ya HPMC iraha ubwitonzi nubushobozi bwa Gel-pel, bigatuma ari ingirakamaro muburyo butandukanye bwa porogaramu muburyo butandukanye.
2. Kubantu bake cyane hamwe nimitungo:
Kimwe mu bintu bigaragara bya HPMC ni ukudakemura mu mazi, bituma habaho amazi menshi. HPMC ikora igisubizo kisobanutse kandi cya viscous mugihe yashonga mumazi, kandi imiterere yacyo irashobora guhinduka muguhindura uburemere bwa molecular hamwe nurwego rwo gusimbuza. Iyi miyoboro ihindagurika nimiterere ikora Hpmc ibereye porogaramu zitandukanye.
3. Imikorere yo gukora firime:
HPMC ifite imiterere myiza ya firime kandi irashobora gukora firime zitoroshye iyo polymer isheshwe mumazi. Uyu mutungo usanga ushyira mubikorwa byimiti no mu biribwa byo guhinga ibisate, ibiryo bikaryama no gutanga imitungo ya bariyeri muri firime ziribwa.
4. Porogaramu y'Ubuvuzi:
HPMC ikoreshwa cyane mu nganda za farumasi kubera imitungo yayo myinshi. Ikoreshwa muri tablet itera nka binder, itunganijwe, ishami rishinzwe film kandi rikora umukozi ukurikiraho. Ubushobozi bwa Polymer bwo kugenzura kurekurwa ibiyobyabwenge no kunoza umutekano wibiyobyabwenge bituma bigira ikintu cyingenzi mumusaruro unyuramo dosiye.
5. Inganda zubwubatsi:
Mu nganda zubwubatsi, HPMC ikoreshwa cyane nkumukozi wijimye, amazi agumana ibikorwa nibikorwa byongerera ibikorwa bya sima ashingiye kuri sima nka minisiteri, imiduka na plasse. Imiterere yacyo ya motelogiya ifasha kunoza imikorere, Kurwanya Sag no Kwizihiza, bikabigira urufunguzo rwingenzi mubikoresho byo kubaka.
6. Ibiryo no kwisiga:
Mu nganda zibiribwa, HPMC ikoreshwa nka Thickener, Emalifier, na Stabilizer mubicuruzwa bitandukanye, harimo amasosi, bifatika, nibikomoka ku mata. Kamere yayo yubusobanuro nubushobozi bwo gukora gels bisobanutse neza bikwiranye no gusaba ibiryo.
Mu buryo nk'ubwo, mu nganda zihirika, HPMC ikoreshwa mu mirimo nka cream, amavuta, na shampogos kubera kubyimba, guturika, no gukora film. Itanga umusanzu mu miterere, viscosity n'umutekano wo kwisiga.
7. Irangi n'amaso:
HPMC ikoreshwa nkuwihishe hamwe nuburyo bwo guhindura amabara ashingiye kumazi hamwe namakoperatifitiye. Itezimbere imiterere ya progaramu ya POAT, nkibitangaje no kurwanya ihohoterwa, mugihe naryo rinoza imikorere rusange yimpute.
8.
Mu kwizihiza, HPMC ikora nkumubyimba n'amazi agumana. Ubushobozi bwayo bwo kugenzura visosi no kunoza uburomu bufite agaciro mugukora ibintu bitandukanye, harimo no guhugira nimpapuro.
9. Sisitemu yo Kugenzurwa:
Kugenzurwa Kurekura Ibikoresho bifatika ni ngombwa mu nganda nyinshi, harimo imiti n'ubuhinzi. HPMC ikoreshwa mugukoresha sisitemu yo kurekura igenzurwa kubera ubushobozi bwayo bwo gukora matrix igenzura umubare wibipimo byo kurekura mugihe.
10. Porogaramu y'ibinyabuzima:
Mu murima wa biomabine na tissue ubwubatsi, HPMC yashakishijwe kubera biocompaget hamwe n'ubushobozi bwo gukora hydrogels. Izi Hydrogels zirashobora gukoreshwa mugutanga ibiyobyabwenge, gukiza ibikomere, na tissue gusubiramo.
11. Ibiranga ibidukikije:
HPMC ifatwa nkinshuti zishingiye ku bidukikije nkuko ikomoka ku mutungo ushoborarwaho kandi ariodegraduable. Gukoresha muburyo butandukanye bujyanye no gukenera ibikoresho birambye kandi byinshuti.
12. INGORANE n'ibitekerezo:
Nubwo HPMC ikoreshwa cyane, inzimizi nyinshi zihari, zirimo imitekerereze yayo kubushyuhe, zigira ingaruka kumitungo yayo. Byongeye kandi, inzira yo guhinduranya no guhindura imiti ya selile isaba kwitondera neza ibidukikije kandi birambye.
13. Kumenyekanisha Ubuyobozi:
Kimwe nibikoresho byose bikoreshwa muri faruceuticals, ibiryo nibindi bicuruzwa byabaguzi, birashishikarirwa ko amahame yashyizweho ninzego zishinzwe kugenzura zikurikiza. HPMC muri rusange ihura nibisabwa kugenzura, ariko ababikora bagomba kubahiriza amabwiriza yihariye kuri buri porogaramu.
Mu gusoza:
HydroxyPropylmethylcellcellCellsellsellse (HPMC) ni polymer itandukanye hamwe nibisabwa muburyo butandukanye. Ihuriro ryihariye ryibikesha, imitungo yo gushinga filime hamwe nubushakashatsi bwamahembe butuma habaho ibyingenzi muri faruceticals, kubaka, ibiryo, kwisiga, kwisiga, amarangi nibindi byinshi. Nk'inganda zikomeje gushaka ibisubizo birambye kandi byiza, HPMC irashobora kuguma umukinnyi ukomeye mubicuruzwa bitandukanye. Nubwo hari ibibazo bimwe na bimwe, ubushakashatsi bukomeje no gutera imbere muri chimie selifire birashobora gukomeza kwagura porogaramu no kunoza imikorere ya HPMC mugihe kizaza.
Igihe cyohereza: Ukuboza-28-2023