Intambwe yumusaruro hamwe nibisabwa bya HPMC

1. Intangiriro kuri Hydroxypropyl Methylcellulose (HPMC)

Hydroxypropyl Methylcellulose (HPMC)ni selile idafite ionic selile ikozwe muri fibre isanzwe ya pamba cyangwa ibiti byimbuto binyuze muguhindura imiti. HPMC ifite amazi meza yo gukomera, kubyimba, gutuza, imiterere ya firime no guhuza ibinyabuzima, bityo ikoreshwa cyane mubwubatsi, ubuvuzi, ibiryo, imiti ya buri munsi nizindi nzego.

2. Intambwe yumusaruro wa HPMC

Umusaruro wa HPMC urimo ahanini intambwe zingenzi zikurikira:

Gutegura ibikoresho

Ibikoresho by'ibanze bya HPMC ni selile-selile isanzwe (ubusanzwe iva mu ipamba cyangwa ibiti), bisaba ubuvuzi bwambere kugirango ikureho umwanda kandi urebe neza ko selile nuburinganire.

Kuvura alkalinisation

Shira selile mumashanyarazi hanyuma wongeremo urugero rukwiye rwa sodium hydroxide (NaOH) kugirango ubyimba selile mubidukikije bya alkaline kugirango ube selile alkali. Iyi nzira irashobora kongera ibikorwa bya selile kandi igategura reaction ya etherification.

Igisubizo cya Etherification

Hashingiwe kuri alkali selulose, imiti ya methylating (nka methyl chloride) hamwe na hydroxypropylating agent (nka oxyde ya propylene) itangizwa kugirango ikore etherification. Ubusanzwe reaction ikorerwa mumashanyarazi afunze cyane. Ku bushyuhe n'umuvuduko runaka, amatsinda ya hydroxyl kuri selile asimburwa na methyl na hydroxypropyl matsinda kugirango hydroxypropyl methylcellulose.

Gukaraba kutabogama

Nyuma yo kubyitwaramo, ibicuruzwa birashobora kuba birimo imiti idakoreshwa hamwe nibindi bicuruzwa, bityo rero birakenewe ko wongeramo igisubizo cya aside kugirango bivurwe, hanyuma ukarabe hamwe namazi menshi cyangwa umusemburo kama kugirango ukureho ibintu bya alkaline bisigaye hamwe n’umwanda.

Umwuma no gukama

Umuti wa HPMC wogejwe ushyizwemo cyangwa ushungurwe kugirango ukureho amazi arenze, hanyuma tekinoroji yo kumisha ubushyuhe buke ikoreshwa mugukora ifu yumye cyangwa flake kugirango ibungabunge umubiri nubumara bya HPMC.

Gusya no kwerekana

HPMC yumye yoherejwe mubikoresho byo gusya kugirango bijanjagure kugirango ubone ifu ya HPMC yubunini butandukanye. Ibikurikira, gusuzuma no gutanga amanota bikorwa kugirango barebe ko ibicuruzwa byujuje ibisabwa bitandukanye.

Gupakira no kubika

Nyuma yo kugenzura ubuziranenge, ibicuruzwa byanyuma bipakirwa ukurikije imikoreshereze itandukanye (nka 25kg / umufuka) bikabikwa ahantu humye kandi bihumeka kugirango birinde ubushuhe cyangwa umwanda.

3. Ibyingenzi byingenzi bikoreshwa muri HPMC

Bitewe no kubyimba kwiza, gukora firime, kubika amazi, emulisitiya hamwe na biocompatibilité, HPMC yakoreshejwe cyane mubikorwa byinshi:

Inganda zubaka

HPMC ninyongera yingirakamaro kubikoresho byubaka, ikoreshwa cyane cyane:

Isima ya sima: kongera ubwubatsi, kubaka neza, no kwirinda gutakaza amazi menshi.

Gufata amatafari: kongera amazi yo gufata tile no kunoza imikorere yubwubatsi.

Ibicuruzwa bya Gypsumu: kunoza imirwanyasuri no kubaka.

Ifu yuzuye: kunoza gufatira hamwe, kurwanya ubukana hamwe nubushobozi bwo kurwanya kugabanuka.

Kwiyoroshya hasi: kongera amazi, kwambara birwanya no gutuza.

Inganda zimiti

HPMC ikoreshwa cyane murwego rwa farumasi nka:

Igikoresho cyo gutwika no gukora firime kubinini byibiyobyabwenge: kuzamura ibiyobyabwenge no kugenzura igipimo cy’ibiyobyabwenge.

Kurambura-kurekura no kugenzura-kurekura imyiteguro: ikoreshwa mubisate bisohora-kurekura hamwe na capsule igenzurwa-bigenga kugenzura ibiyobyabwenge.

Ibisimbuza Capsule: bikoreshwa mugukora capsules zikomoka ku bimera (capsules yimboga).

4. Inganda zikora ibiribwa

HPMC ikoreshwa nk'inyongera y'ibiryo ahanini kuri:

Thickener na emulsifier: bikoreshwa mubicuruzwa bitetse, jellies, amasosi, nibindi kugirango utezimbere uburyohe bwibiryo.

Stabilisateur: ikoreshwa muri ice cream n'ibikomoka ku mata kugirango wirinde kugwa kwa poroteyine.

Ibiryo bikomoka ku bimera: bikoreshwa nkibyimbye kubiribwa bishingiye ku bimera kugirango bisimbuze stabilisateur zikomoka ku nyamaswa nka gelatine.

Inganda zikora imiti ya buri munsi

HPMC ni ikintu cy'ingenzi mu kwisiga no kwita ku muntu ku giti cye:

Ibicuruzwa byita ku ruhu: bikoreshwa mu mavuta yo kwisiga, masike yo mumaso, nibindi kugirango bitange amazi kandi bihamye.

Shampoo na douche gel: kongera ifuro ihamye no kunoza ubwiza.

Amenyo yinyo: ikoreshwa nkibyimbye nubushuhe kugirango utezimbere uburyohe.

Irangi na wino

HPMC ifite imiterere-yerekana firime nziza kandi ihagarikwa kandi irashobora gukoreshwa kuri:

Irangi rya Latex: kunoza uburiganya na rheologiya y'irangi kandi wirinde kugwa.

Ink: Kunoza imvugo no kunoza ubuziranenge bwo gucapa.

Ibindi Porogaramu

HPMC irashobora kandi gukoreshwa kuri:

Inganda zubutaka: Nka binder, uzamure imbaraga zubutaka bwa ceramic.

Ubuhinzi: Bikoreshwa muguhagarika imiti yica udukoko hamwe nimbuto zimbuto kugirango utezimbere umukozi.

Inganda zikora impapuro: Nka agent zingana, uzamure amazi arwanya impapuro.

HPMCni ibikoresho bikoreshwa cyane bya polymer, bikoreshwa cyane mubwubatsi, ubuvuzi, ibiryo, imiti ya buri munsi, impuzu nizindi nganda. Igikorwa cyacyo cyo kubyaza umusaruro gikubiyemo ibintu fatizo byo kwisiga, alkalisation, etherification, gukaraba, gukama, gusya nizindi ntambwe, buri murongo uhuza ubwiza bwibicuruzwa byanyuma. Hamwe no kunoza ibisabwa byo kurengera ibidukikije no kuzamuka kw’isoko, ikoranabuhanga ry’umusaruro wa HPMC naryo ririmo kunozwa kugira ngo inganda nyinshi zikenewe.