Sodium carboxymethyl selile (uzwi kandi nka: sodium carboxymethyll selile, carboxymethyl selile,Cmc, Carboxymethyl, sodium ya selile, umunyu wa sodium wa Catboxy Methyl Cellulose) niyo ikoreshwa cyane kandi amafaranga menshi akoreshwa kwisi muri iki gihe ubwoko bwa selile.
CMC-NA NUGUBUKURA, ni ugutanga selile hamwe na Glucose Impamyabumenyi ya Glucose ya 100-2000, hamwe na misa ya molekolar ya 242.16. Ifu yera cyangwa granular ifu. Impumuro nziza, itaryoshye, idafite uburyohe, hygroscopique, ihungababunganya mubintu byiza.
Imitungo Yibanze
1. Imiterere ya molekuline ya sodium carboxymethylcellsellse (cmc)
Yabaye bwa mbere n'Ubudage mu 1918, kandi bwaraparitse mu 1921 kandi bugaragara ku isi. Umusaruro wubucuruzi kuva wagezweho mu Burayi. Muri kiriya gihe, byari umusaruro mubi, bikoreshwa nka colloid na binder. Kuva mu 1936 kugeza 1941, ubushakashatsi bwifashe inganda ya sodiyumu carboxymethyl selile yakagombye gukora cyane, kandi amashyirahamwe menshi ashimishije yavumbuwe. Mu Ntambara ya Kabiri y'Isi Yose, Ubudage bwakoresheje sodium carboxymethymethylcellse mu bucuruzi bwa sintetike. Hercules yakoraga sodium carboxymethylcellse ku nshuro ya mbere muri Amerika mu 1943, kandi ikora sodium ya sodium yatunganijwe mu 1946, yamenyekanye nk'ibiribwa byiza. Igihugu cyanjye cyatangiye kubyemeza mu myaka ya za 70, kandi cyakoreshejwe cyane mu myaka ya za 90. Nicyo gikoreshwa cyane kandi ingano nini ya selile kwisi muri iki gihe.
Formula yubaka: C6H7O2 (OH) 2OCH2Coona MoleCulat formulaire: C8h10No7na
Iki gicuruzwa ni umunyu wa sodium wa selile carboxymethyl ether, fibre ya aiyoni
2. Kugaragara kwa sodium carboxymethyl selile ya selile (cmc)
Iki gicuruzwa ni umunyu wa sodium wa selile carboxymethyl ether, ifu ya anionic ether cyangwa granule yera cyangwa amata .7 g / cm3, hygroscopique. Biroroshye gutatana mumazi kugirango ukore igisubizo cyiboneye, kandi ihujwe no gucika intege nka etanol [1]. PH ya 1% Igisubizo cya 1% ni 6.5-8.5, mugihe ph> 10 cyangwa <5, viscosiya rya Mucillage igabanya cyane, kandi imikorere nibyiza mugihe PH = 7. Bizahatira gushyushya, viscosity irazamuka vuba aha 20 ° C, kandi ihinduka buhoro kuri 45 ° C. Gushyushya igihe kirekire hejuru ya 80 ° C birashobora kwamagana colloid kandi bigabanya cyane viscosity n'imikorere. Birashonje byoroshye mumazi, kandi igisubizo kirasobanutse; Birahamye cyane mu gisubizo cya alkaline, ariko biroroshye hydrolyzed iyo ihuye na aside, kandi izacika intege mugihe agaciro ka PH ari 2-3, kandi izakwitwara hamwe ninyungu za polvalent.
Intego nyamukuru
Ikoreshwa nkubwinshi munganda zibiribwa, nkumutwara ibiyobyabwenge mu nganda za farumasi, kandi nkumukozi wa binder na kurwanya inganda za miri ya buri munsi. Mu icapiro no gusiga irangi, bikoreshwa nk'abanterankunga ikiringira abakozi bakomeye no gucapa. Mu nganda za peteroli, irashobora gukoreshwa nkibigize amazi yo kugarura amavuta. [2]
Kurongora
Sodium carboxymethylcellse ntaho ihuriye na acide ikomeye, gukosora iminyururu, hamwe nabandi byuma nka alumini, mercure, na zinc. Iyo PH iri munsi ya 2, kandi iyo ivanze na 95% Ethanol, imvura izabaho.
Sodium carboxymethyl selile irashobora gukora co-agglomera na gelatine na pectin, kandi irashobora kandi gukora ibintu bigoye hamwe na corogents.
Ubukorikori
CMC mubisanzwe anionmer polymer polymer yateguwe yo gufata selile karemano hamwe na aside ya alkali na aside ya monochlorondoace na monochlolorondoacetic hamwe nuburemere bwa molekiro bwa 6400 (± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 ± 1 Ibicuruzwa byingenzi nibicuruzwa ni sodium chloride na sodium glycolate. CMC ni iy'uburinganire busanzwe. Ishirahamwe ry'Umuryango w'abibumbye n'ubuhinzi (FAO) n'umuryango w'ubuzima ku isi (NINDE) bitwa "wahinduwe na selile yahinduwe".
Ibipimo ngenderwaho kugirango bipime ubuziranenge bwa CMC nurwego rwo gusimbuza (DS) kandi ubuziranenge. Mubisanzwe, imitungo ya CMC iratandukanye niba DS itandukanye; urwego rwo hejuru rwo gusimbuza, gukomera kwikebagura, kandi ibyiza byo gukorera hamwe no gutuza kubisubizo. Nk'uko amakuru abitangaza, gukorera mu mucyo bya CMC nibyiza mugihe urwego rwo gusimburwa ari 0.7-1.2, kandi virusi yikibazo cyacyo nicyo kinini mugihe agaciro cya PH ni 6-9. Kugirango tumenye neza, hiyongereyeho guhitamo umukozi wabuze, ibintu bimwe bigira ingaruka ku rwego rwo gusimburwa no kweza bigomba gusuzumwa, nk'imibanire iri hagati y'amafaranga ya Alkali na Handigo, Ibirimo Sisitemu, ubushyuhe, PH agaciro, igisubizo hamwe numunyu nibindi.
Imiterere
Mu rwego rwo gukemura ikibazo cy'ibikoresho fatizo (ipamba yatunganijwe ikozwe mu misozi y'ipamba), mu myaka yashize, imitwe ya kera y'ubushakashatsi mu gihugu cyanjye yakoranye n'inzego z'umuceri, ipamba y'ubutaka (imyanda yo mu masasu), na Bean curd dregs kubyara CMC neza. Igiciro cyo gukora kiragabanuka cyane, gifungura isoko nshya yibikoresho fatizo bya CMC umusaruro winganda kandi tukamenya imikoreshereze yubwoko. Ku ruhande rumwe, igiciro cyo gukora cyagabanutse, kandi kurundi ruhande, CMC iratera imbere kubwuburinganire buhebuje. Ubushakashatsi n'iterambere rya CMC byibanda cyane cyane ku guhindura ikoranabuhanga risanzwe no guhanga udushinga, kimwe n'ibicuruzwa bishya bya CMC bifite imitungo idasanzwe, nk '"uburyo bworoshye bwo gutera imbere mu mahanga kandi byakoreshejwe cyane. Ubwoko bushya bwa CMC yahinduwe hamwe nubukungu bwisumbuye bwakozwe. Bitewe nurwego rwo hejuru rwo gusimbuza hamwe no gukwirakwiza kimwe mu buryo bwo gukwirakwiza mu buryo butunguranye, hashobora gukoreshwa mu buryo bunini bw'inganda z'umusaruro no gukoresha ibidukikije kugira ngo bihuze ibisabwa. Ku rwego mpuzamahanga, ubwo bwoko bushya bwa CMC yahinduwe kandi yitwa "Polyanionic TOLLECOSE (PAC, Poly Ainic Thunic)".
umutekano
Umutekano Mukuru, Adi ntabwo akeneye amabwiriza, kandi amahame yigihugu yateguwe [4].
gusaba
Iki gicuruzwa gifite imikorere yo guhuza, kubyimba, gushimangira, guteranya, kugumana amazi no guhagarikwa.
Gusaba CMC mubiryo
FAO kandi yemeje ikoreshwa rya CMC yera mubiryo. Byemejwe nyuma yubushakashatsi bukabije nubushakashatsi nuburozi. Ifatwa ryiza (adi) ryibipimo mpuzamahanga ni 25mg / (kg · t), ibyo ni 1.5 g / d kumuntu. Byaravuzwe ko abantu bamwe badafite ubutunzi ubwo agera ku bami 10. CMC ntabwo ari stabilizer nziza gusa hamwe nubwinshi bwa porogaramu zibiribwa, ariko kandi ifite umutekano mwiza kandi ushongeshejwe, kandi urashobora kuzamura uburyohe bwibicuruzwa hanyuma ukandagira umwanya wo kubika. Amafaranga akoreshwa mumata ya soya, ice cream, ice cream, jelly, ibinyobwa, ibinyobwa, nimboga ni 1% kuri 1.5%. CMC irashobora kandi gukora itara ryerekanwe na vinegere, isosi yimboga, amavuta yimbuto, umutobe wimboga, umutobe wimboga, nibindi 0.2%. By'umwihariko, ifite ibyiza bitera imikorere kumavuta yinyamanswa, proteyine nibisubizo bitangaje, bituma bituma bitera imibumbanyi hamwe nibikorwa bihamye. Kubera umutekano wacyo no kwizerwa, dosage yacyo ntabwo igarukira nimbuto yigihugu yisuku yisuku adi. CMC yakomeje gutera imbere mu biryo, n'ubushakashatsi ku ikoreshwa rya sodium Carboxymethylcellsellsellsellsellsellse muri divayi nayo yarakozwe.
Ikoreshwa rya CMC mubuvuzi
Mu nganda za farumasi, irashobora gukoreshwa nka stabilizeri ya emulizer kugirango inshinge, binder hamwe numukozi ushinga filime mubisate. Abantu bamwe bagaragaje ko CMC ari utwara ibiyobyabwenge iteka kandi byizewe kubijyanye nubushakashatsi bwibanze kandi bwinyamanswa. Gukoresha CMC nkibikoresho bya membrane, uburyo bwa dosiye yahinduwe bwumujyi gakondo waygin Shengji, YanGyIn Shengji Membrane, arashobora gukoreshwa ibikomere byibikorwa bya Demabrasion hamwe nibikomere bitesha umutwe. Ubushakashatsi bwinyamanswa bwerekanye ko filime irinda kwandura ibikomere kandi ntaho itandukaniro rikomeye ryimyambarire ya gauze. Ku bijyanye no kugenzura ibikomere bikabije amaraso no gukiza byihuse, iyi filime irashimishije cyane kuruta imyambarire ya gauze, kandi ifite ingaruka zo kugabanya impamyabumenyi y'intangiriro no kurakara. Imyiteguro ya firime ikozwe muri polyvinyl Inzoga: Sodium Carboxymethyll Cellulose: PolycarboyAthylene mugihe cya 3: 6: 1 nigipimo cyiza, kandi igipimo cyo kurekura kandi kirekura cyiyongereye. Imyiteguro yo kwitegura, igihe cyo kwitegura mu cyuho no mu kanwa no gukora imiti mu gutegura byose byateye imbere cyane. Bupivane ni anesthe ikomeye, ariko rimwe na rimwe birashobora kubyara ingaruka zikomeye zumutima mugihe uburozi. Kubwibyo, mugihe BURPINACaine ikoreshwa cyane mubuvuzi, ubushakashatsi ku gukumira no kuvura ibiganiro byuburozi byahoraga byitabwaho cyane. Ubushakashatsi bwa farumasi bwagaragaje ko imbiko mboneragihugu nk'ibintu bikonje byateguwe hamwe n'umuti wa Bupivaine ushobora kugabanya cyane ingaruka z'ibiyobyabwenge. Mu kubaga Prk, ikoreshwa ry'imikorere yo hasi hamwe n'ibiyobyabwenge bitari byo kurwanya imivurungano bihujwe na CMC birashobora kugabanya ububabare bwa nyuma. Gukumira ingufu za pentoneal na kugabanya inzitizi zororoka ni kimwe mubibazo bireba cyane kubagwa amavuriro. Ubushakashatsi bwerekanye ko CMC iruta cyane sodium hyaluronate mu kugabanya urugero rwa posita ya personelative, kandi irashobora gukoreshwa nkuburyo bwiza bwo kubuza peritoneal. CMC ikoreshwa muri catheter artrial artrial trasion yibiyobyabwenge byo kurwanya kanseri y'umwijima, bishobora kongera gukora cyane imivugo ya Liver, ishobora gutanga umusaruro w'ibibyimba byo ku isi, bishobora kongera gukomera cyane mu bibyimba, byongerera cyane imbaraga zo kurwanya umubyimba, zongerera imbaraga zo kurwanya ikibyimba, no kunoza ingaruka zo kuvura. Mu miti yinyamaswa, CMC nayo ifite uburyo butandukanye. Byaravuzwe [5] ko intanga ngore na 1% cmc igisubizo cyintama zigira ingaruka zikomeye kubangamira gukumira dystocia na munda nyuma yo kubagwa tractratique mu matungo.
CMC mubindi bikorwa byinganda
Mubyifuzo, CMC irashobora gukoreshwa nkabakozi barwanya ubutaka, cyane cyane kuri hydrophobic crobrics fibrics ya fibre ya syntheptique, nziza cyane kuruta karboxymethyl fibre.
CMC irashobora gukoreshwa mu kurinda amariba yamashanyarazi nkabakozi bo mubyondo na bakozi bashinzwe amazi mumavuta. Igipimo kuri buri mavuta neza ni 2.3T yo kuringaniza amariba mato na 5.6t kumariba maremare;
Mu nganda zimbuto, zikoreshwa nkumukozi wambaye, wijimye wo gucapa no gusiga irangi paste, gucapa imyenda no kurangiza. Iyo ikoreshwa nkumukozi wa siporo, irashobora kunonosora no gusya, kandi biroroshye kubahiriza; Nkumukozi ukomeye, dosage yayo iri hejuru ya 95%; Iyo ukoreshejwe nkumukozi wambaye, imbaraga nuburyo bworoshye bwa firime yubunini byanonosowe cyane; Hamwe na sibroin yavuguruwe muri membrane igizwe na carboxymethyl selile ikoreshwa nka matridase ya glucose na glucose ikozwe ifite ubushishozi bwo hejuru kandi buhamye. Ubushakashatsi bwerekanye ko igihe ibihugu bya silica byateguwe hamwe nigisubizo cya CMC hamwe na 1% (W / V), imikorere ya chromatografiya, imikorere ya chromatographic yisahani yoroheje yateguwe. Muri icyo gihe, isahani yoroheje yatinyutse mu buryo bworoshye ifite imbaraga zikwiye, zikwiriye tekinike zitandukanye zo gutoranya, byoroshye gukora. CMC ifite ubushishozi kuri fibre nyinshi kandi irashobora kunoza amasani hagati ya fibre. Guhagarara kwa vino yayo birashobora kwemeza isano yuzuye, bityo bigatuma imikorere yo kuboha. Irashobora kandi gukoreshwa nkumukozi urangije amasambo, cyane cyane kugirango uciriritse anti-winkle kurangiza, bizana impinduka zirambye kubitambara.
CMC irashobora gukoreshwa nkumukozi urwanya edulsientation, Emulsifuer, atarasa, urwego, kandi akize kugirango aho bihuze. Irashobora gukora ibikubiye mu ikondo ryagabanijwe neza muri soteve, kugirango igikote kitababaje kuva kera. Byakoreshejwe kandi mu gushushanya. .
Iyo CMC ikoreshwa nka fliccculant, nibyiza kuruta sodium gluconate mugukuraho calcium. Iyo bikoreshejwe nkigikorwa cya CATI, ubushobozi bwayo bushobora kugera kuri 1.6 ML / G.
CMC ikoreshwa nkumukozi ukina nimpapuro muruganda, kirashobora kunoza imbaraga zumye nimbaraga zitose zimpapuro, kimwe no kurwanya peteroli, kwinjiza ink.
CMC ikoreshwa nka hydrool muri kwisiga no kwigomeka mumajwi, kandi dosage yayo ni 5%.
CMC irashobora gukoreshwa nka flicculant, umukozi wahemu, Emulsifuer, ubumwe, amazi, kandi ibikoresho, ibikoresho byo gushinga filime, kandi ibikoresho, plastics, ifiriti, ifirimbi, ifirimbi, buri munsi Imiti nizindi nzego, kandi kubera imikorere yayo nziza nuburyo butandukanye, bihora ufungura imirima mishya isaba, kandi ibyiringiro byisoko birakabije.
Ingamba
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(2) gufata neza iki gicuruzwa ni 0-25mg / kg · d.
Amabwiriza
Kuvanga CMC mu buryo butaziguye amazi kugirango ukore glue ya parike kugirango ukoreshe nyuma. Mugihe ushiraho kolee ya CMC, banza ongeramo amazi meza mumaso ya tank hamwe nigikoresho gishimishije, kandi mugihe igikoresho gishimishije cya CMC mu kigega, bityo igikoresho gihamye cya CMC mu kigega, kugirango CMC ihumanye neza Hamwe namazi, CMC irashobora gusenya byimazeyo. Mugihe usenya CMC, impamvu yatumye bigomba kumenaka kandi bigashirwaho ubudahwema ni "gukumira ibibazo bya CMC bishonga amazi", no kongera igiciro cyivumburwa na CMC. Igihe cyo gukangurira ntabwo kimeze nkigihe cya CMC kugirango gishongesheje rwose. Ni ibitekerezo bibiri. Muri rusange, igihe cyo gukangurira ni kigufi cyane kuruta igihe cya CMC cyo gushonga rwose. Igihe gisabwa kuri bibiri biterwa nibihe byihariye.
Ishingiro ryo kumenya igihe gishimishije ni: iyoCmcntabwo yakwirakwijwe mu mazi kandi nta bihuru binini binini, gukangurwa birashobora guhagarara, bigatuma cmc n'amazi byinjira no kwinjiza hamwe muburyo buhagaze.
Ishingiro ryo kugena igihe gisabwa kuri CMC kugirango ishonge rwose ni izi zikurikira:
(1) CMC n'amazi birahujwe rwose, kandi nta gutandukana-amazi akomeye hagati yombi;
(2) Paste ivanze iri muburyo bumwe, kandi ubuso burasa neza kandi bworoshye;
. Kuva icyo gihe CMC ishyirwa mubigega ivanze ikavanga namazi mugihe CMC yashonze rwose, igihe gisabwa kiri hagati yamasaha 10 na 20.
Igihe cyo kohereza: APR-26-2024