Kwiga Kubisaba HPMC mumarira asanzwe-avanze

Abstract:Ingaruka zibintu bitandukanye za hydroxypropyl methylcellse ether kumitungo ya pertar isanzwe yumye yize. Ibisubizo byerekanye ko: hamwe no kwiyongera kubiri muri selile ether, guhuza ubukana byagabanutse, kandi igihe cyo gushinga cyagabanutse. Imbaraga, 7D n'i 28 zitera imbaraga zagabanutse, ariko muri rusange imikorere ya minisiteri yumye yumye yatejwe imbere.

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Mu 2007, Minisiteri esheshatu na Komisiyo z'igihugu byatanze "integuza ku kubuza urubuga rwo kuva kuri minisiteri mu mijyi imwe n'imwe mu gihe ntarengwa". Kugeza ubu, imijyi 127 yo mu gihugu hose imaze gukora umurimo wo "kubuza" minisiteri, yazanye iterambere rititiriwe mu iterambere rya minisiteri ivanze. amahirwe. Hamwe n'iterambere rikomeye rya minisiteri yumye mu rugo no mu bijyanye no kubaka mu gihugu no mu mahanga, ivanze ry'umusaruro unyuramo kandi ugenda utanga umusaruro w'ibicuruzwa. iterambere ryiza kandi ritondekanye. Kugeza ubu, nkibikoresho bifatika, bivanze bivuye kuri miniverte bikoreshwa cyane cyane muburyo bwo guhuza, kandi ugereranije ni bike bikoreshwa wenyine. By'umwihariko, hari ubwoko bwinshi bwibikorwa mubintu bimwe na bimwe biruka-bivanze byimikorere, ariko muri minisiteri isanzwe yumye, ariko hagomba kwitabwaho cyane kubikorwa bya miniverti. Muri minisiteri isanzwe yumye, Ether, Ether, Ether akina uruhare rwo kugumana amazi, kubyimba, no kuzamura imikorere yubwubatsi. Imikorere myiza yo kugumana amazi yemeza ko minisiteri yumye itavaho itazatera umucanga, ifu n'imbaraga no kugabanya imbaraga kubera kubura amazi no kutagira sima; Ingaruka zingana zongera cyane imbaraga zuburyo bwa minisiteri itose. Uru rupapuro rukora ubushakashatsi kuri gahunda kuri porogaramu ya selile muri minisiteri isanzwe yumye, ihuza ibisobanuro byuburyo bwo gukoresha ibintu bifatika muburyo busanzwe bwumye.

1. Ibikoresho bya fatizo nuburyo bukoreshwa mukizamini

1.1 Ibikoresho fatizo byikizamini

Ingwate yari P. 042.5

1.2 Uburyo bw'ikizamini

Icyitegererezo cyo kwitegura no kwipimisha imikorere byakozwe ukurikije JCJ / T 70-2009 uburyo bwibanze bwigihe cyipimisha imikorere yo kubaka minisiteri.

2. Gahunda y'Ikizamini

2.1 formula ku kizamini

Muri iki kizamini, ingano ya buri kintu kibisi cya 1 cya toni 1 ya plastar ya plastar ikoreshwa nkimiterere yibanze yikizamini, kandi amazi niwo gukoresha amazi 1 ya minisiteri yumye.

2.2 Gahunda yihariye

Gukoresha iyi formula, ingano ya hydroxypropyl methylcellse ether yongeyeho kuri buri gice cya peteroli ya hydroxyproppopyl methylcellses ether, Guhoraho, Gutanga ubucucike, bugena igihe, n'imbaraga zo kwikuramo imiyoboro isanzwe y'amahoro, kugira ngo bayobore neza imikoreshereze myiza yo gutanga imisaruro yo ku miterere ya miniver

3. Ibisubizo n'ibisubizo n'isesengura

3.1 Ibisubizo by'ibizamini

Ingaruka zinzira zitandukanye za hydroxypropyl methylcellsellse ether kumasoko yo kugumana amazi, ubucucike, bugena igihe, hamwe nimbaraga zisanzwe zumye za plastar minisiteri.

3.2 Isesengura ryibisubizo

Birashobora kugaragara nkingaruka zamafaranga atandukanye ya hydroxypropyl methylcellellse ether kumasoko, ubucucike, hamwe nimbaraga zidasanzwe za pertar minisiteri ivanze yumye. Hamwe no kongera ifumbire ya selile, urugero rw'amazi yo guhohotera amazi narwo rugenda rwiyongera, kuva kuri 86.2% mugihe hydroxyPro sellexilose ntabwo ivanze, igihe cya metero Umubare wogumana amazi ugera kuri 96.3%, bigaragaza ko ingaruka zo kugumana amazi ya propyl methyl methyl nziza cyane; Guhuza buhoro buhoro bigabanuka buhoro buhoro munsi yingaruka zamazi ya propyl methyl methyl methyl mether (gukoresha amazi kuri toni ya minisiteri ntigihinduka mugihe cyubushakashatsi); Ubucucike bugaragara bwerekana inzira yo hepfo, byerekana ko ingaruka ziterwa n'amazi za Propyl Methyl Methyl Yotwo ari byo byongera ubunini bwa minisiteri itose kandi igabanya ubucucike; Igihe cyo gutora buhoro buhoro hamwe no kwiyongera kw'ibirimo bya hydroxypropyl methyl the sellease, hamwe no gukoresha amafaranga ya 8h. Imbaraga zitera 7D na 28d zagabanutse (igipimo kinini, igabanuka rigaragara). Ibi bifitanye isano no kwiyongera mubunini bwa minisiteri no kugabanuka mubucucike bugaragara. Ongeraho HydroxyPropyl Methyl Cellulose Ether irashobora gukora umwobo ufunze muri minisiteri ikomantaye mugihe igenamigambi no gukomera kwa minisiteri. Micropores itezimbere kuramba.

4. Ibyiciro kugirango usabe selile ether muri minisiteri isanzwe yumye

1) guhitamo ibicuruzwa bya selile. Muri rusange, niko virusi ya selile, ni ko ingaruka zayo zo kugumana amazi, ahubwo ni hejuru cyane, haba hasi cyane, bikaba bibi ku mbaraga n'imikorere y'ubwubatsi; Impeta ya selile ya selile ni hasi ugereranije na minisiteri yumye. Bavuga ko ari byiza, byoroshye gushonga. Munsi ya dosage imwe, impeta nziza, ingaruka nziza zo kugumana amazi.

2) guhitamo selile ether dositage. Duhereye ku bizamini n'ibisubizo by'ibizamini by'ingaruka z'ibirimo byagutse kuri churiel ku mikorere ya minisiteri ihumeka, Ibyiza, imikorere myiza n'ibice bine by'ibidukikije byo kumvikana Hitamo Dosage ikwiye. Igipimo cya HydroxyPropyl Methyl Cellulose ether muri minisiteri isanzwe yumye cyane niba umubare wa hydroxypropyl methyl wongeyeho mumafaranga make. Impanuka nziza; Igipimo cya HydroxyPropyl Methyl Cellulose ether muri minisiteri idasanzwe ya plastant irwanya amashanyarazi agera kuri 3 kg / t.

3) Gusaba selile ether mumahoro isanzwe yumye. Muburyo bwo gutegura minisiteri isanzwe yumye, urugero rukwiye rushobora kongerwaho, nibyiza hamwe na kanseri y'amazi kandi bikagira ingaruka zingana na selile, kugirango bigabanye ibiciro byumusaruro, no kubika umutungo; Niba ikoreshwa wenyine kuri selile ether, imbaraga zo guhunika ntishobora kuzuza ibisabwa, kandi umubare ukwiye wongeyeho ifu ya latex irashobora kongerwaho; Bitewe numubare muto wa mirtar afmixture, ikosa rikoreshwa ni rinini iyo rikoreshejwe wenyine. Ubwiza bwibicuruzwa byumye.

5. Imyanzuro n'ibitekerezo

1) Muri minisiteri isanzwe yumye-ivanze, hamwe no kongera ibikubiye muri hydroxyPropyl methylcellsel methylcellse ether, igipimo cyo kugumana amazi gishobora kugera kuri 96.3%. Imbaraga zo gutuza za 28d zagabanutse, ariko imikorere rusange ya minisiteri yumye yumye mugihe ibirimo bya hydroxypropyl methyl methyl byari bisanzwe.

2) Muburyo bwo gutegura minisiteri isanzwe yumye, ether ether hamwe na virusi ikwiye kandi nziza igomba gutorwa, kandi igipimo cyacyo kigomba kugenwa neza binyuze mubushakashatsi. Bitewe numubare muto wa mirtar afmixture, ikosa rikoreshwa ni rinini iyo rikoreshejwe wenyine. Birasabwa kuvanga nabatwara mbere, hanyuma wongere umubare wo kongeramo kugirango umenye neza ubuziranenge bwibicuruzwa byumye.

3) Mortar yumye-ivanze ni inganda zigaragara mu Bushinwa. Muburyo bwo gukoresha ibidukikije bya minisiteri, ntitugomba gukurikira ubuhumyi ubwinshi, ahubwo twita cyane kubiciro byubwiza no kugabanya ibiciro byumusaruro, dushishikarize gukoresha ibisigazwa byinganda, kandi rwose tugera ku kuzigama no kugabanya imbaraga zo kuzigama no kugabanya imbaraga.


Igihe cyagenwe: Feb-22-2023