HydroxyPropyl Methylcellse (HPMC)ni selile itari ionic yahamagaye cyane mubikoresho byubaka, imiti, ibiryo, kwisiga, kwisiga, kwisiga hamwe nizindi nzego zinganda. Ifite ibintu byinshi byiza byumubiri, bituma bikora neza muburyo butandukanye.
1. Kugaragara no kwikeba
HPMC mubisanzwe ni ifu yera cyangwa yera, idafite impumuro nziza, itaryoshye kandi idafite uburozi. Irashobora gushonga mumazi akonje hamwe nibiti bimwe na bimwe binyuranye (nkibi bivanze nkibisobanuro bya ethanol / amazi na acetone / amazi), ether na chloroform. Bitewe na kamere itari ionic, ntabwo izakora ibintu bya electrolytic mu gisubizo cy'amazi kandi ntazagira ingaruka cyane ku gaciro ya PH.
2. Viccosity na roologiya
HPMC igisubizo gitangaje gifite uburimbane na thixotropy. Ubwoko butandukanye bwamapitefori®hpmc ifite ubushyuhe butandukanye, kandi urwego rusanzwe ni 5 kugeza 100000 MPA · s 100%, 20%. Igisubizo cyacyo cyerekana ko pseudopplastity, ni ukuvuga kogosha ibintu, kandi birakwiriye kubisabwa nkibisohoka, gukurura, kumeneka, ibitekerezo, nibindi bisaba uburyo bwiza.
3. Gelation
Igihe HPMC yashyushye mumazi, gukorera mu mucyo bisubizo biragabanuka na gel byakozwe ku bushyuhe runaka. Nyuma yo gukonja, leta ya Gel izasubira mubikorwa. Ubwoko butandukanye bwa HPMC bufite ubushyuhe bwa gel, muri rusange hagati ya 50 na 75 ° C. Uyu mutungo ni ngombwa cyane mubisabwa nko kubaka capsules na farumasi.
4. Igikorwa cyo hejuru
Kuberako molekile ya HPMC ikubiyemo amatsinda ya hydrophilic na hydrophobike, yerekana ibikorwa bimwe na bimwe byo hejuru kandi birashobora gukinisha ibizunguruka, gutatana no guhanagura inshingano. Kurugero, mumagana no kubeshya, HPMC irashobora guteza imbere imihanda ya emulion kandi ikakumira imyanda.
5. Hygroscopitity
HPMC ifite hygroscoficity runaka kandi irashobora gukuramo ubuhehere mubidukikije bihebuje. Kubwibyo, muburyo bumwe, kwitondera bigomba kwishyurwa mugupakira akadodo kugirango wirinde kwinjiza neza no guterana.
6. UMUTUNGO WA FILM
HPMC irashobora gukora firime itoroshye kandi ibonerana, ikoreshwa cyane mubiryo, imiti (nko kugoreka. Kurugero, mumiti yimari ya farumasi, firime ya HPMC irashobora gukoreshwa nkigikorwa cyo kunoza ibiyobyabwenge no kugenzura.
7. Bioquatis n'umutekano
HPMC ntabwo ari uburozi kandi itagira ingano, kandi irashobora guhumurizwa numubiri wumuntu, bityo ikoreshwa cyane mumiti yubuvuzi nibiryo. Nka Pharmasiotique yihangana, mubisanzwe ikoreshwa mugutanga ibinini byarakaye, ibishishwa bya capsus, nibindi
8. PH Guharanira igisubizo
HPMC ihagaze neza muri PH amanota ya 3 kugeza 11, kandi ntabwo yangiritse byoroshye cyangwa ngo igabanuke na alkali, bityo irashobora gukoreshwa muburyo butandukanye bwa shimi, nkibikoresho byubaka hamwe nibikorwa bya buri munsi na farumasi.
9. Kurwanya Umunyu
Igisubizo cya HPMC kirahagaze neza muminyuhunyuke kandi ntabwo ari ibintu byoroshye cyangwa bidahwitse kubera impinduka muri Sisitemu nziza muri sisitemu zimwe zirimo umunyu (nka ce ubwe Pertar).
10. Umutekano mu bushyuhe
Slowltl®hpmc ifite umutekano mwiza mubushyuhe bwinshi, ariko irashobora gutesha agaciro cyangwa guhinduranya mugihe uhuye nubushyuhe bwinshi mugihe kirekire. Irashobora gukomeza gukora imikorere myiza mubushyuhe runaka (mubisanzwe munsi ya 200 ° C), birakwiriye rero kubikorwa byo gutunganya ubushyuhe.
11. Umutekano wimiti
Hpmcni ushikamye kumucyo, oxdants hamwe nibikoresho bisanzwe, kandi ntibikorwa byoroshye nibintu byo hanze. Kubwibyo, birashobora gukoreshwa mubicuruzwa bisaba kubika igihe kirekire, nkibikoresho byubaka n'imiti.
HydroxyPropyl methylcellse yakoreshejwe cyane mu nganda nyinshi kubera koroheje cyane. Mu nganda zubwubatsi, irashobora gukoreshwa nka sima yubutaka; Mu nganda za farumasi, irashobora gukoreshwa nka farumasi yihangana; Munganda zibiri, ni ibiryo bisanzwe. Nibintu bidasanzwe byumubiri bituma Hpmc ibikoresho byingenzi bya polymer.
Igihe cyagenwe: Feb-10-2025