Ni ibihe bintu byerekeranye na HPMC?

Nibihe bintu bya momologiya byaHpmc?

HydroxyPropyl methylcellse (HPMC) ni polymer itandukanye isanga mu nganda zinyuranye, harimo imiti, kubaka, ibiryo, ibiryo, no kwisiga, cyane cyane bitewe n'imiterere yihariye y'amatongi. RHEOLOLOLOLOLOLOLOLOLOLOLOLOLOLOLY ni kwiga ibikoresho byo gutembera no guhindura ibikoresho, no gusobanukirwa imiterere ya HPMC ni ngombwa kugirango utezimbere imikorere yayo muburyo butandukanye.

IYI VICOSITION: HPMC yerekana imyitwarire ya pseudoplastique cyangwa inkombe yoroheje, bisobanura uko bigaragara ko igabanuka hamwe no kongera umubare munini. Uyu mutungo ningirakamaro mubisabwa nkibintu bitera imiti, aho byemerera kuvoma byoroshye, gukwirakwiza, no gusaba. Guscosity birashobora gutunganizwa no guhindura urwego rwo gusimbuza (DS) nuburemere bwa molekile ya HPMC.

Thixotropy: thixotropy bivuga imyanya ya Gel-Sol yagaragajwe nibikoresho bimwe na bimwe munsi yo guhangayika. Abanya HPMC Gels yashizweho kuruhuka arashobora gusenyuka munsi yogosha no kugarura imiterere yabo mugihe imihangayiko ikuweho. Uyu mutungo ni mwiza mubisabwa nkamashusho, aho bikubuza gukanda mugihe cyo gusaba ahubwo byemeza ko igiti gikwiye kimaze gusaba.

Hydration: HPMC ni hygroscopique kandi irashobora gukuramo amazi, ikaganisha kubyimba no kwiyongera kugaragara. Urwego rwa Hydration ruterwa nibintu nkubushyuhe, PH, na ionic imbaraga zumuco ukikije. Hydration igira uruhare runini mu kugenzura irekurwa ry'ibiyobyabwenge muri farumasi no gukomeza ubushuhe mu bicuruzwa.

Ubushyuhe bumva:HpmcIbisubizo byerekana ubushyuhe bushingiye ku bushyuhe, hamwe na vinosity igabanuka nkubushyuhe bwiyongera. Ariko, iyi myitwarire irashobora gutandukana bitewe nibintu nka polymer kwibanda hamwe nigisubizo ph. Ubushyuhe bwikirere ningirakamaro mubisabwa nkibikoresho byubwubatsi, aho bigira ingaruka ku gikorwa no gushiraho igihe.

Umunyu Wibitekerezo: Ibisubizo bya HPMC birashobora kwerekana sensitivite ku munyungo, hamwe n'unyunyu tutera imbaraga za vicosity abandi bitera kugabanuka kwa vicosi. Iki kintu cyitirirwa imikoranire hagati ya molekile ya HPMC na Ion mubisubizo. Ubushishozi bwumunyu nibyingenzi mubijyanye na farumasi hamwe nibicuruzwa aho ibigomba kugenzurwa neza.

Kwishingikiriza ku buryo bwo kwishingikiriza: Ibintu byerekeranye bya HPMC bishingiye cyane ku gipimo cy'inkombe cyakoreshejwe. Ku gipimo cyo hasi, uruzinduko ruri hejuru kubera ubwitonzi bwa molekile, mu gihe ku gipimo cy'iminsi mike, vicosity igabanuka kubera kogosha inkono. Gusobanukirwa kwishingikiriza ku buryo bwo kwishingikiriza ni ngombwa mugutegura gutunganya ibintu bitandukanye.

Guhagarika ibice: HPMC irashobora gukora nkumukozi uhagarika uduce mumazi kubera kubyimba no guhungabanya umutekano. Ifasha gukumira gutura ibice bikomeye, kwemeza ko isaranganya rimwe no gukurikiranwa mubicuruzwa nkamashusho, ihindagurika, hamwe na farumasi.

Gushiraho Gel:HpmcIrashobora gushiraho geles mubihe byinshi cyangwa imbere yabakozi bahungabanya nkamaryo. Ibi bikoresho byerekana amashusho kandi bikoreshwa mubisabwa nko gutanga ibiyobyabwenge bigenzurwa, aho hakenewe kurekura ibintu bifatika bisabwa.

Ibintu byimiterere ya HPMC, harimo vicosity, Thixotropy, hydration, ubushyuhe n'umunyu wishingikirije, uhagarike agace, ugira uruhare runini mu kugena imikorere itandukanye yinganda. Gusobanukirwa no kugenzura ibi bintu ni ngombwa kugirango utegure uburyo bwo gushyiraho no gutunganya ibicuruzwa bishingiye kuri HPMC.