HydroxyPropyl methylcellse (HPMC) ni polymer isanzwe ikoreshwa muri farumasi, kwisiga, ibikoresho byibiribwa, hamwe nibindi bikoresho bitandukanye. Hakoreshejwe cyane kubera biocompaget, bidafite uburozi, nubushobozi bwo guhindura ibintu byimyuka yibisubizo. Ariko, ni ngombwa kumva uburyo washonga Hpmc neza gukoresha imitungo yayo neza.
Amazi: HPMC irashonje cyane mumazi, bigatuma guhitamo guhitamo porogaramu nyinshi. Ariko, igipimo cyo guseswa kirashobora gutandukana bitewe nibintu nkubushyuhe, PH, hamwe nicyiciro cya HPMC ikoreshwa.
Ibicuruzwa bya kama: Indangamico zitandukanye zishobora gusesa HPMC kuri ibintu bitandukanye. Ibicuruzwa bimwe bisanzwe bivuga:
Inzoga: IsOpropanol (IPA), Ethanol, methanol, nibindi byinshi bikoreshwa muri farumasi kandi birashobora gushonga neza HPMC.
Acetone: Acetone nigisubizo gikomeye gishobora kugushonga HPMC neza.
Ethyl Acetate: Nubundi buryo bwa kama bushobora gusesa HPMC neza.
Chloroform: Chloroform ni ikintu gikabije kandi kigomba gukoreshwa witonze kubera uburozi bwayo.
Dimethyl Sulfoxide (DMSO): DMSO ni polar adrotic fagititike ishobora gushonga ibice byinshi, harimo na HPMC.
Propaylene Glycol (PG): PG ikunze gukoreshwa nkinkunga ya farumasi. Irashobora gusesa HPMC neza kandi akenshi ikoreshwa muguhuza namazi cyangwa ubundi buryo bwo gukemura.
Glycerin: Glycerin, uzwi kandi nka glycerol, ni ukwishyuza muri farumasi no kwisiga. Bikoreshwa kenshi mu guhuza amazi kugirango ishonge HPMC.
Polyethylene Glycol (Peg): Peg ni polymer ufite ibibazo byiza cyane mumazi hamwe nibiti byinshi. Irashobora gukoreshwa mugushonga HPMC kandi akenshi ikoreshwa mugihe gihamye-kurekura.
Kwiyongera: Haba hari abasibanye barashobora gufasha mu iseswa rya HPMC bagabanya impagarara z'ubuso no kuzamura iyonga. Ingero zirimo hagati ya 80, sodium lauryle sulfate (sls), na polsorbate 80.
Acide ikomeye cyangwa ibirindiro: Mugihe bidakunze gukoreshwa kubera impungenge z'umutekano no gutesha agaciro HPMC, acide ikomeye (urugero: sodium hydroxide) irashobora gushonga HPMC mubihe bikwiye. Ariko, ibintu bikabije p p p ph birashobora gutera gutesha agaciro polymer.
Abakozi batoroshye: Abakozi bamwe batongana nka Cyclodextrins barashobora gukora ibintu byo kwinjiza hamwe na HPMC, gufasha mu iseswa no kuzamura bike.
Ubushyuhe: Mubisanzwe, ubushyuhe bwo hejuru bwongerera igipimo cyivumburwa cya HPMC mumazi. Ariko, ubushyuhe bwinshi bukabije bushobora gutesha agaciro polymer, ni ngombwa rero gukora mubushyuhe butekanye.
Guhagarika imashini: Gukomera cyangwa kuvanga birashobora koroshya gusenya HPMC yongera umubano hagati ya polymer na socieve.
Ingano yinshi: Ifu yifu ya HPMC izashonga byoroshye kuruta ibice binini biterwa nubuso bwiyongera.
Ni ngombwa kumenya ko guhitamo kumuntu no kuvugwa biterwa na porogaramu yihariye kandi byifuzwa nibicuruzwa byanyuma. Guhuza nibindi bikoresho, ibitekerezo byumutekano, hamwe nibisabwa kugenzura nabyo bigira ingaruka kumahitamo yubusa nubusa. Byongeye kandi, ni ngombwa gukora ubushakashatsi bwo guhuza no kwipimisha gushikama kugirango tumenye neza ko gahunda yo kuvugurura itagira ingaruka mbi cyangwa imikorere y'ibicuruzwa byanyuma.
Igihe cyohereza: Werurwe-22-2024