Hydroxypropyl methylcellulose (HPMC) ni polymer itandukanye ikomoka kuri selile, isanzwe ibaho polysaccharide iboneka murukuta rw'utugingo ngengabuzima. Bikunze gukoreshwa mubikorwa bitandukanye nka farumasi, ibiryo, kwisiga, ubwubatsi, nibindi byinshi kubera imiterere yihariye.
HPMC ikomatanyirizwa hamwe na chimique ihindura selile ikoresheje etherification reaction. By'umwihariko, ikorwa mu kuvura selile hamwe na oxyde ya propylene na methyl chloride kugirango itangize hydroxypropyl na methyl mumatsinda ya selile. Ubu buryo butanga amazi ya elegitoronike ya polymer hamwe nibintu byiza ugereranije na selile kavukire.
Uburyo bwo kubyaza umusaruro:
Umusaruro wa HPMC urimo intambwe nyinshi:
Isoko rya Cellulose: Cellulose, mubisanzwe ikomoka kumiti cyangwa ipamba, ikora nkibikoresho byo gutangira.
Etherification: Cellulose ikorerwa etherification, aho ikora na oxyde ya propylene na methyl chloride mugihe cyagenwe kugirango itangize hydroxypropyl na methyl.
Isuku: Ibicuruzwa bivamo bigenda intambwe yo kweza kugirango bikureho umwanda nibidakenewe-bicuruzwa.
Kuma no gusya: HPMC isukuye noneho yumishwa hanyuma igasya ifu nziza cyangwa granules, bitewe nibisabwa.
HPMC yerekana ibintu byinshi bitandukanye, bigatuma ikoreshwa muburyo butandukanye:
Amazi meza: HPMC irashonga mumazi akonje, ikora ibisubizo bisobanutse neza. Ibisubizo birashobora guhindurwa muguhindura urwego rwo gusimbuza (DS) ya hydroxypropyl na methyl matsinda.
Gukora firime: Irashobora gukora firime zoroshye kandi zifatanije mugihe zumye, bigatuma zikoreshwa muburyo bwo gutwika imiti munganda zimiti ninganda zibiribwa.
Kubyimba: HPMC nigikoresho cyiza cyane, gitanga igenzura ryubwiza muburyo butandukanye nka amavuta yo kwisiga, amavuta, amarangi.
Ihamye: Yerekana imiti ihamye kandi irwanya mikorobe.
Guhuza: HPMC irahujwe nibindi bintu byinshi, harimo surfactants, umunyu, hamwe nuburinzi.
HPMC isanga porogaramu nyinshi mu nganda zitandukanye:
Imiti ya farumasi: Bikunze gukoreshwa nka binder, agent-coating firime, modifier modifier, hamwe na matrix ihoraho-irekura muburyo bwa tablet.
Inganda zikora ibiribwa: HPMC ikora nkibibyimbye, stabilisateur, na emulisiferi mubicuruzwa byibiribwa nka sosi, imyambarire, hamwe nubutayu.
Ubwubatsi: Mu nganda zubaka, HPMC ikoreshwa nkibyimbye mubicuruzwa bishingiye kuri sima, bitezimbere imikorere no gufatana.
Ibicuruzwa byumuntu ku giti cye: Biboneka mu kwisiga, shampo, hamwe nu menyo wamenyo nkibikoresho byibyimbye, emulifier, na firime yahoze.
Irangi hamwe na Coatings: HPMC itezimbere imiterere yimiterere yamabara hamwe nigitambaro, byongera imikoreshereze yimikorere.
HPMC, ikomoka kuri selile ikoresheje reaction ya etherification, ni polymer itandukanye hamwe nibikorwa bitandukanye mubikorwa bitandukanye. Imiterere yihariye, nkibishobora gukama amazi, ubushobozi bwo gukora firime, hamwe nubunini bwimbitse, bituma iba ingenzi mumiti yimiti, ibiryo, ubwubatsi, nibicuruzwa byita kumuntu.
Igihe cyo kohereza: Apr-17-2024