Nibihe bishonga bya HPMC polymer?

HPMC (Hydroxypropyl Methylcellulose) ni amazi ya elegitoronike ya polymer ikoreshwa cyane muri farumasi, ibiryo, ubwubatsi, amavuta yo kwisiga nizindi nganda. HPMC ni igice cya sintetike ya selile ikomoka kubutaka bwahinduwe na chimique ya selile karemano, kandi mubisanzwe bikoreshwa nkibyimbye, stabilisateur, emulifier na afashe.

Imiterere yumubiri ya HPMC

Ingingo yo gushonga ya HPMC iraruhije cyane kuko aho gushonga ntigaragara neza nkibikoresho bisanzwe bya kristu. Ikibanza cyacyo cyo gushonga kigira ingaruka kumiterere ya molekuline, uburemere bwa molekuline no kurwego rwo gusimbuza hydroxypropyl na methyl, bityo birashobora gutandukana ukurikije ibicuruzwa byihariye bya HPMC. Mubisanzwe, nka polymer-yamazi ashonga, HPMC ntabwo ifite aho ishonga kandi isobanutse, ariko yoroshye kandi ikangirika mubipimo byubushyuhe runaka.

Urwego rwo gushonga

Imyitwarire yubushyuhe bwa AnxinCel®HPMC iraruhije, kandi imyitwarire yayo yangirika yubushyuhe ikunze kwigwa nisesengura rya termogravimetric (TGA). Uhereye kubitabo, urashobora gusanga urwego rwo gushonga rwa HPMC ruri hagati ya 200°C na 300°C, ariko iyi ntera ntabwo igereranya ingingo yo gushonga yibicuruzwa byose bya HPMC. Ubwoko butandukanye bwibicuruzwa bya HPMC bushobora kugira ingingo zitandukanye zo gushonga hamwe nubushyuhe bwumuriro bitewe nibintu nkuburemere bwa molekile, urugero rwa ethoxylation (urwego rwo gusimburwa), urwego rwa hydroxypropylation (urwego rwo gusimburwa).

Uburemere buke bwa HPMC: Mubisanzwe gushonga cyangwa koroshya ubushyuhe buke, kandi birashobora gutangira pyrolyze cyangwa gushonga nka 200°C.

Uburemere bukabije bwa HPMC: Polimeri ya HPMC ifite uburemere buke bwa molekuline irashobora gusaba ubushyuhe bwo hejuru gushonga cyangwa koroshya bitewe n'iminyururu ndende ya molekile, kandi mubisanzwe bitangira pyrolyze no gushonga hagati ya 250°C na 300°C.

Ibintu bigira ingaruka kumashanyarazi ya HPMC

Uburemere bwa molekuline: Uburemere bwa molekuline ya HPMC bugira ingaruka zikomeye kumwanya wabwo. Uburemere buke bwa molekuline busanzwe busobanura ubushyuhe buke bwo gushonga, mugihe uburemere buke bwa molekile bushobora kuganisha hejuru.

Impamyabumenyi yo gusimbuza: Urwego rwa hydroxypropylation (ni ukuvuga igipimo cyo gusimbuza hydroxypropyl muri molekile) n'urwego rwa methylation (ni ukuvuga igipimo cyo gusimbuza methyl muri molekile) ya HPMC nacyo kigira ingaruka ku gushonga kwacyo. Mubisanzwe, urwego rwo hejuru rwo gusimbuza rwongera imbaraga za HPMC kandi rugabanya aho rushonga.

Ibirimo ubuhehere: Nkibikoresho bikurura amazi, aho gushonga kwa HPMC nabyo bigira ingaruka kubirimo. HPMC ifite ubuhehere bwinshi irashobora guhura nogusenyuka cyangwa gusenyuka igice, bikavamo ihinduka ryubushyuhe bwumuriro.

Ubushyuhe bwumuriro nubushyuhe bwa HPMC

Nubwo HPMC idafite aho ishonga cyane, ituze ryumuriro nigikorwa cyingenzi cyerekana. Dukurikije isesengura rya thermogravimetric (TGA), HPMC ubusanzwe itangira kubora mubushyuhe bwa 250°C kugeza 300°C. Ubushyuhe bwihariye bwo kubora buterwa nuburemere bwa molekile, urugero rwo gusimbuza nibindi bintu bifatika na chimique bya HPMC.

Kuvura ubushyuhe muri porogaramu ya HPMC

Mubisabwa, gushonga ingingo hamwe nubushyuhe bwa HPMC nibyingenzi. Kurugero, mu nganda zimiti, HPMC ikoreshwa nkibikoresho bya capsules, ibifuniko bya firime, hamwe nabatwara imiti irekura. Muri iyi porogaramu, ubushyuhe bwumuriro wa HPMC bugomba kuba bujuje ibisabwa kugirango ubushyuhe butunganyirizwe, bityo rero gusobanukirwa imyitwarire yubushyuhe hamwe no gushonga ingingo ya HPMC ningirakamaro mugucunga ibikorwa.

Mubikorwa byubwubatsi, AnxinCel®HPMC ikoreshwa nkibyimbye muri minisiteri yumye, ibifuniko hamwe nibifatika. Muri iyi porogaramu, ubushyuhe bwumuriro wa HPMC nabwo bugomba kuba murwego runaka kugirango barebe ko butangirika mugihe cyo kubaka.

HPMC, nkibikoresho bya polymer, ntabwo bifite aho bihurira, ariko byerekana koroshya na pyrolysis biranga ubushyuhe runaka. Urwego rwo gushonga ruri hagati ya 200°C na 300°C, hamwe nu ngingo yihariye yo gushonga biterwa nibintu nkuburemere bwa molekile, urugero rwa hydroxypropylation, urugero rwa methylation, nubushuhe bwa HPMC. Muburyo butandukanye bwo gukoresha, gusobanukirwa iyi miterere yubushyuhe ningirakamaro mugutegura no gukoresha.