Numero yuruhererekane rwa hydroxypropyl methylcellse?

HydroxyPropyl Methylcellse (HPMC)ni uburyo bwahinduwe bwa selile ikoreshwa cyane muburyo butandukanye nka faruceticals, umusaruro wibiryo, no kubaka. Ni urugo rutandukanye, akenshi rukoreshwa nkuwabyimbye, binder, umukozi ushinga filimi, na stabilizer. Ariko, ntabwo ifite "umubare wuruhererekane" muburyo gakondo, nkibicuruzwa cyangwa umubare wa numero ushobora gusanga mubindi bikoresho byo gukora. Ahubwo, HPMC igaragazwa n'imiterere yacyo n'imiterere y'ibiranga, nk'icyiciro cyo gusimbuza no kureba.

Amakuru rusange yerekeye hydroxyPropyl methylcellse (HPMC)

Imiterere yimiti: HPMC ikorwa nubupfura buhindura imiti binyuze mu gusimbuza hydroxyl (-Oh) amatsinda hamwe n'amatsinda ya hydroxyPropy na methyproppopy na methyproppopy na methylProppopy na methylo. Gusimbuza guhindura imitungo ya selile, bikaba byoroshye mumazi kandi bikabitanga imitungo yihariye nkubushobozi bwo kunonosora bwa firime, ubushobozi bwo guhuza, nubushobozi bwo kugumana ubushuhe.

Ibipimo rusange no kwinanga

Kumenyekanisha HydroxyPropyl Methylcellse mubisanzwe bishingiye ku masezerano atandukanye yo kwita izina asobanura imiterere yimiti n'imiterere:

Umubare wa Cas:

Serivisi yo gukuramo imiti (cas) igenera ikiranga kidasanzwe kuri buri kintu cyose cya shimi. Umubare wa Cas kuri HydroxyPropyl Methylcellse ni 90045-3. Uyu ni umubare usanzwe wakoreshejwe na chimiste, abatanga, hamwe ninzego zigenga zerekeza kubintu.

Inchi no Kumwenyura:

Inchi (Imiti Mpuzamahanga ya chimique) nubundi buryo bwo kwerekana imiterere yimiti yibintu. HPMC yaba ifite umurongo muremure wa Inchi ugereranya imiterere yacyo muburyo busanzwe.

Kumwenyura (kwinjiza molecular yinjiza umurongo wa sisitemu) nindi sisitemu ikoreshwa muguhagararira molekile muburyo bwanditse. HPMC ifite kandi kode yometseho, nubwo yaba igoye cyane kubera imiterere nini kandi itandukanye yimiterere yacyo.

Ibicuruzwa Byihariye:

Mu isoko ry'ubucuruzi, HPMC ikunze kumenyekana n'imibare y'ibicuruzwa, ishobora gutandukana nuwabikoze. Kurugero, utanga isoko arashobora kugira amanota nka HPMC K4M cyangwa HPMC E15. Ibi bikoresho bikunze kuvuga visosi ya polymer kubisubizo, bigenwa nurwego rwibibyimba na hydroxy osiproire kimwe nuburemere bwa molekile.

Amanota asanzwe ya hydroxyproppopyl methylcellse (HPMC)

Ibiranga hydroxyproppopyl methylcellse vary hashingiwe ku rwego rwo gusimbuza amatsinda ya methyl na hydroxyProppoyle, hamwe nuburemere bwa molekile. Ibi bitandukana byerekana vicosity ya HPMC no kukengurwa mumazi, nayo igira ingaruka kubisabwa munganda zitandukanye.

Hasi nimbonerahamwe yerekana amanota atandukanye ya hydroxyproppopyl methylcellse:

Ibigize birambuye hamwe na HPMC

Imitungo yumubiri ya hydroxypropyl methylcellsellse iterwa ahanini nubwomburwa amatsinda ya hydroxyl muri molekile ya selile. Dore ibintu byingenzi:

Urwego rwo gusimbuza (DS):

Ibi bivuga amafaranga angahe mumatsinda ya hydroxyl yasimbuwe na metoyl cyangwa amatsinda ya hydroxyPropyle. Urwego rwo gusimbuza rugira ingaruka ku bushobozi bwa HPMC mu mazi, ubuyobe bwayo, n'ubushobozi bwayo bwo gushinga filime. Ibisanzwe DS kuri HPMC kuva kuri 1.4 kugeza 2.2, bitewe nicyiciro.

Vicosity:

Amanota ya HPMC ashyirwa mu byiciro ukurikije virusi yabo mugihe yashonga mumazi. Ikirere kirenze urugero hamwe nurwego rwo gusimburwa, hejuru cyane. Kurugero, HPMC K100m (hamwe nurwego rwo hejuru rwamamare) rukoreshwa mu kugenzurwa n'ibiyobyabwenge, mu gihe amanota yo hasi ya HPMC nka HPMC K4M akoreshwa mu bikoresho n'ibiryo.

Amazi yonyine:

HPMC irashonje mumazi kandi ikora ibintu nka gel mugihe yasheshejwe, ariko ubushyuhe na pH birashobora guhindura ibyokuntu byonyine. Kurugero, mumazi akonje, irashonga vuba, ariko kwikeba kwayo birashobora kugabanuka mumazi ashyushye, cyane cyane mubihe byinshi.

Ubushobozi bwo gukora firime:

Kimwe mu bintu by'ingenzi biranga hydroxyproppopyl methylcellse nubushobozi bwayo bwo gukora firime yoroshye. Uyu mutungo utuma ukwiranye no gukoresha mubyoroheje bikora, aho bitanga hejuru, igenzurwa-kurekura. Ni ingirakamaro kandi munganda zikoreshwa kugirango utezimbere ubuzima nubuzima.

Ifaranga:

Ku bwibanze hamwe n'ubushyuhe, HPMC irashobora gukora kals. Uyu mutungo ni ingirakamaro muri farumasi yimiti, aho ikoreshwa mugukora sisitemu yo kugenzurwa.

Gusaba HydroxyPropyl methylcellse

Inganda za farumasi:

HPMC ikoreshwa nka bunder muri tablet foire, cyane cyane mugukurwa no kurekura no kugenzurwa-sisitemu yo kurekura. Ikora kandi nkumukozi wo gutora ibinini na capsules kugirango igenzure irekurwa ryikintu gikora. Ubushobozi bwayo bwo gukora firime zihamye hamwe na gels nibyiza kuri sisitemu yo gutanga ibiyobyabwenge.

Inganda

Mu nganda zibiribwa, HPMC ikoreshwa nkumukozi wijimye, Emulsifuer, na Stabilizer mubicuruzwa bitandukanye, harimo isosi, imyambaro, n'ibicuruzwa bitetse. Ifasha kunoza imiterere no kwagura ubuzima buke bwo kugabanya igihombo cyubushuhe.

Kwisiga no kwita ku muntu ku giti cyabo:

HPMC ikoreshwa cyane yo kwisiga, aho ikora nkumubyimba na stilizer muri cream, amavuta, shampoos, nibindi bicuruzwa byita kugiti cyawe. Ubushobozi bwayo bwo gukora uruganda rufite akamaro cyane muriyi porogaramu.

Inganda zubwubatsi:

Mu nganda zubwubatsi, cyane cyane muri sima na plaque bakoraga, HPMC ikoreshwa nkumukozi ugumana amazi. Ifasha kunoza imikorere no kuzamura imitungo yo guhuza ibikoresho.

Ibindi bikorwa:

HPMC nayo ikoresha mu nganda zimbuto, amatara yimpapuro, ndetse no mumusaruro wa firime ya Biodegradable.

HydroxyPropyl Methylcellse (HPMC)Ese uruganda rukora cyane rwakoreshejwe mu nganda nyinshi kubera imitungo yihariye nko gukoresha film, ubushobozi bwo gukemura, no kugumana amazi. Mugihe idafite "umubare wuruhererekane" muburyo busanzwe, bugaragazwa nibiranga imiti nkumubare wa cas (90045--65-3) hamwe nicyiciro cyihariye (urugero: HPMC E4M). Urutonde rwinshi rwitsinda rya HPMC riboneka ryemeza ko rikoreshwa mumirima itandukanye, kuva ifariti mubiryo, kwisiga, no kubaka.