HydroxyPropyl Methylcellse (HPMC)Ese amazi ya polymer akoreshwa cyane muri farumasi, kubaka, ibiryo, kwisiga hamwe nizindi nzego. Umutungo wacyo wa viscosity nigipimo cyingenzi kugirango upime imyitwarire yacyo munsi yibidukikije. Gusobanukirwa umutungo wa viscosity wa HPMC igisubizo kiradufasha kurushaho kumva imyitwarire n'imikorere muri porogaramu zitandukanye.
1. Imiterere yimiti numutungo wa HPMC
HPMC iboneka kubihindura imiti ya selile karemano, cyane cyane byakozwe na hydroxy opripylepylepyleapy na methylatiya molekile. Muburyo bwa shimi ya HPMC, intangiriro ya methyl (-och₃) na hydroxyPropyl (-umusoro) bituma amazi ashonga amazi kandi afite ubushobozi bwiza bwo guhinduranya amazi. IMIKORESHEREZO YIMUSOMO WAWE MU BIKORWA BY'AMARIMO MU BIKORWA BITANDUKANYE N'UBURENGANZIRA BUKURIKIRA N'IBIKORWA BYINSHI NK'UBUYOBOZI BWA MOLECULER, Urwego rwo gusimbuza, n'ibindi
2. Isano iri hagati ya viscosity no kwibanda
Uruzinduko rwamaganya ya Sportsl®hpmc igisubizo cyibitangaza mubisanzwe byiyongera hamwe no kwibanda. Ibi ni ukubera ko mubihe byibanze, imikoranire iri hagati ya molekile yongerewe imbaraga, iva mubitero byiyongera. Ariko, kwikebagura no gukurura HPMC mumazi nabyo bigira ingaruka kuburemere bwa molekile. HPMC ifite uburemere bwimbitse bukabije bugaragaza ubushyuhe bwo hejuru, mugihe uburemere buke bwa molecular bufite hasi.
Mugihe cyo hasi: Igisubizo cya HPMC cyerekana ubushyuhe bwo hasi kurwego rwo hasi (nka 0.5%). Muri iki gihe, imikoranire iri hagati ya molekile irakomeye kandi amazi ni meza. Mubisanzwe bikoreshwa mubisabwa nkibisohoka no kurekurwa ibiyobyabwenge.
Mugihe cyibanze: Mubice byinshi (nka 2% cyangwa birenga), viscosiya igisubizo cya HPMC cyibisubizo bya HPMC yiyongera cyane, yerekana imiterere isa nibisubizo bya colloidal. Muri iki gihe, amazi yigisubizo agerwaho kugirango ahangane cyane.
3. Isano iri hagati ya viscosity nubushyuhe
Ibyatsi bya HPMC igisubizo gitangaje cyumva cyane ubushyuhe. Mugihe ubushyuhe buri hagati ya molecule yiyongera, kandi imikoranire hagati ya HPMC ihinduka intege nke, bikaviramo kugabanuka kwa vino. Ibi biranga bituma porogaramu ya HPMC ku bushyuhe butandukanye bwerekana ko hakurikijwe. Kurugero, munsi yubushyuhe bwinshi, ubushyuhe bwa HPMC bugabanuka, bukaba ari ngombwa cyane muri farumasi, cyane cyane mubiyobyabwenge bikomeza gusohora dosiye, aho guhindura ubushyuhe bishobora kugira ingaruka kumutekano ningaruka zigisubizo.
4. Ingaruka za PH kuri viscosity
Ibyatsi bya HPMC yo gukemura ibitaramo birashobora kandi kwibasirwa na PH agaciro k'igisubizo. Nubwo HPMC ari ibintu bitari ionic, hydrophilitity na hydhiletikes byumutungo wibasiwe cyane nuburyo bwa molecular hamwe nigicuruzwa. Ariko, mubihe bya acide cyane cyangwa alkaline, ubwitonzi nubushake bwa HPMC burashobora guhinduka, bityo bigira ingaruka kuri viscosiya. Kurugero, mubihe bya acide, kudukura kwa HPMC birashobora gucika intege nke, bikavamo becosiya; Mugihe uri munsi ya alkaline, hydrolysis ya HPMC irashobora gutuma uburemere bwayo bwo kugabanuka, bityo bikagabanya urusyo.
5. Uburemere bwa molekile na visosity
Uburemere bwa molekilar nikimwe mubintu byingenzi bigira ingaruka kuri viscosiya igisubizo cya HPMC. Uburemere bwo hejuru bumfuruka bwongera ubwitonge no guhuriza hamwe molekile, bikavamo ubuyobe bwiyongera. Uburemere buke bwa molekilel®hpmc bufite ibibazo byiza mumazi no hejuru. Ibisabwa bitandukanye mubisanzwe bisaba guhitamo HPMC hamwe nuburemere butandukanye bwa moleka. Kurugero, mumajyambere no kumeneka, uburemere bwinshi bwa moleclar HPMC mubisanzwe byatoranijwe kugirango amenye neza kandi ameze neza; Mugihe uri mu myiteguro ya farumasi, uburemere bwa molecular buke HPMC irashobora gukoreshwa mugukemura igipimo cyibiyobyabwenge.
6. IMIKORANIRE N'IMIKORERE YA HAAR na SSCOSIty
Ibyatsi bya HPMC igisubizo gisanzwe mubisanzwe bihinduka hamwe nigipimo cyo gusiganwa, kwerekana imyitwarire yuburyo busanzwe bwa pseudologiya. Amazi ya pseudoplastique ni amazi afite ubukana buhoro buhoro agabanuka buhoro buhoro hamwe no kwiyongera kw'ikirenga. Ibi biranga bituma igisubizo cya HPMC cyo gukomeza ubushyuhe bwinshi ku gipimo cyo hasi mugihe gishyizwe mu bikorwa, kandi kizamura amazi hejuru yinkombe. Kurugero, mu nganda zo gupakira, igisubizo cya HPMC gikeneye kwerekana ubushishozi bwo hejuru ku gipimo cyo hepfo mugihe gikoreshwa kugirango akemure neza kandi mugihe cyo kubaka, mugihe cyiyongera, ni ngombwa kongera imigenzo yo kubaka amazi menshi.
7. Gusaba no kwerekana ibimenyetso bya HPMC
Ibiranga viscosity byaHpmcBikore bikoreshwa cyane mumirima myinshi. Kurugero, mu nganda za farumasi, HPMC ikunze gukoreshwa nkigiti cyaranze ibiyobyabwenge, kandi amabwiriza yarwo akoreshwa mu kugenzura umubare wibiyobyabwenge; Mu nganda zubwubatsi, HPMC ikoreshwa nkubwinshi bwo kunoza imikorere ibikorwa n'amazi ya minisiteri no kubyihanganira; Mu nganda zibiribwa, HPMC irashobora gukoreshwa nkababyimbye, emalifier na stilizer kugirango bateze imbere uburyohe no kugaragara kubiryo.
Ibiranga visosity bya biranga Amaganya ya Sporcel®hpmc igisubizo cyibitangaje nurufunguzo rwo gusaba mumirima itandukanye. Gusobanukirwa umubano wacyo nibintu nkibitekerezo, ubushyuhe, PH, uburemere bwa molekile hamwe nigipimo cyo gusiganwa ku buryo bukomeye bwo guhitamo imikorere no kunonosora ingaruka zikoreshwa.
Igihe cya nyuma: Jan-27-2025