HydroxyPropyl Methylcellse (HPMC)ni ugukoresha selile yakoreshejwe hamwe nuburyo butandukanye bwa porogaramu, cyane cyane mubijyanye na farumasi, kwisiga, ibiryo, nibikoresho byo kubaka. Ntabwo ari igisubizo, ariko polymer-yoroshye amazi ashobora gushonga mumazi kandi agakora igisubizo cya colloidal. Kudakemurwa byamasoma.PhPmc biterwa numubare numwanya wa methyl na hydroxypropyl empiens mumiterere yayo.
1. Imiterere y'ibanze ya hydroxypropyl methylcellse
HydroxyPropyl Methylcellse iboneka by methylation na hydroxy opepy of selile. Cellulose ubwayo ni amagambo asanzwe yo hejuru cyane ahari abari mu rukuta rw'ibimera. Imiterere yimiti ya HPMC igizwe ahanini nibice bya glucose, bikaba bya molekile ndende ndende ihujwe na β-1,4 glycosic. Muri iyi miterere ya molekelar, amatsinda amwe ya hydroxyl yasimbuwe na methyl (-och₃) na hydroxyproppopyl (-C₃hhOh), bikagutanga cyane hamwe nibindi bimi byumubiri na shimi.
Kudakemurwa na HPMC bigira ingaruka kumiterere ya molekelar kandi mubisanzwe bifite ibiranga bikurikira:
Amazi yonyine: HPMC irashobora gukora igisubizo cya vino mumazi kandi ishonga vuba. Kudakemurwa kwayo bifitanye isano rya hafi nubushyuhe bwamazi nuburemere bwa molekile ya HPMC.
Ubu buryo bwo hejuru: Mubitekerezo runaka, igisubizo cya HPMC cyerekana ubushyuhe bwo hejuru, cyane cyane muburemere bwa molekile no kwibanda cyane.
Umutekano mu bushyuhe: HPMC ifite umutekano mwiza ku bushyuhe runaka kandi ntabwo byoroshye kubora, bityo bifite inyungu zimwe mubikorwa byo gutunganya ubushyuhe.
2. Kukemera hpmc
HPMC nigikoresho cyo gukosora amazi, ariko ntabwo gisenyutse nibisubizo byose. Imyitwarire yayo isenyutse ifitanye isano na polarity ya solive hamwe nubufatanye hagati ya molekile ya soleventi na molekile ya HPMC.
Amazi: HPMC irashobora gushonga mumazi. Amazi nigisubizo cyacyo gikunze kugaragara, kandi mugihe cyo guturika, gutwika amatwi Urwego rwo gusesa rugira ingaruka ku bintu nka uburemere bwa moleki, urwego rw'imvururu na hydroxy ofleepypylepyley, ubushyuhe, na PH agaciro kamazi. Mubisanzwe, gukemurwa kwa HPMC nibyiza mubidukikije ph.
Ibicuruzwa bya kama: hpmc hafi idahujwe mubintu byinshi byamarika, nka alcool, abatanga, na hydrocarbone. Ni ukubera ko imiterere yaryo irimo molecular irimo hydrophilique amatsinda na methyl na methphilic methyle na hydlexppepoyl. Nubwo ifite ubuhinzi bukomeye kumazi, buhuza nabi nibintu bya kama.
Amazi ashyushye yoroheje: Mu mazi ashyushye (ubusanzwe 40 ° C kugeza 70 ° C), HPMC irashonga vuba kandi igisubizo cyangiritse cyerekana neza. Ubwo ubushyuhe bwongera urujijo, igipimo cyo gusebanya no kukesha kwiyongera, ariko ku bushyuhe bwinshi, ubushyuhe bw'igisubizo bushobora kugira ingaruka.
3. Gusaba HPMC
Bitewe n'amazi meza, uburozi buke, hamwe na vicosity yo guhinduka, HPMC ikoreshwa cyane mu nganda zitandukanye.
Inganda za farumasi: Mu nganda za farumasi, HPMC ikoreshwa cyane mu gutegura irambye ikuramo ibiyobyabwenge, ibinini bibumba byinshi, Gels, n'ibiyobyabwenge. Irashobora gufasha ibiyobyabwenge gushonga mumazi kandi bigenga igipimo cyo kurekura ibiyobyabwenge.
Inganda zibiribwa: HPMC, nkibihingwa byibiribwa, bikunze gukoreshwa mu guhiga, kubyimba, no gucogora. Mubicuruzwa bitetse, birashobora kunoza umucunga no gutuza. HPMC ikunze gukoreshwa muri ice cream, ibinyobwa nibiryo bibyibushye.
Inganda zubwubatsi: Mu nganda zubwubatsi, HPMC ikunze gukoreshwa nkuwabyibushye yo kubaka minisiteri, ishobora kuzamura imikorere yubwubatsi, ishobora kuzamura imikorere yubwubatsi, ihagarikwa ryamazi kandi rikagira imbaraga za minisiteri.
Kwisiga: Muri kwisiga, Slocksl®hpmc ikoreshwa cyane nkuwabyimbye, uhagarike umukozi, kandi ukoreshwa cyane mubicuruzwa nka cream, kandi na gels, na pasika.
Hpmcni ugushonga amazi kandi viscous inkongizo zikomoka zirashobora gukora igisubizo cyiboneye mumazi. Ntabwo ari igisubizo, ahubwo ni urugwiro rwinshi rushobora gushonga mumazi. Kudakemurwa byagaragaye cyane cyane mubikewe mumazi, ariko bidahwitse mubintu byiza byinshi. Ibi biranga HPMC bikoreshwa cyane mu nganda nyinshi, harimo imiti, ibiryo, kubaka, no kwisiga.
Igihe cyagenwe: Gashyantare-17-2025