Imiti ya farumasi
Hydroxypropyl methylcellulose (HPMC) ni umweru cyangwa amata yera, impumuro nziza, uburyohe, ifu ya fibrous cyangwa granule, gutakaza ibiro kumisha ntibirenza 10%, gushonga mumazi akonje ariko ntabwo ari amazi ashyushye, buhoro buhoro mumazi ashyushye Kubyimba, peptisation, no gukora a viscous colloidal solution, ihinduka igisubizo iyo ikonje, igahinduka gel iyo ishyushye. HPMC ntishobora gukemuka muri Ethanol, chloroform na ether. Irashobora gushonga mumashanyarazi avanze ya methanol na methyl chloride. Irashobora kandi gushonga mumashanyarazi avanze ya acetone, methyl chloride na isopropanol hamwe nindi miti ikungahaye. Igisubizo cyacyo cyamazi kirashobora kwihanganira umunyu (igisubizo cyacyo cya colloidal ntabwo cyangizwa numunyu), naho pH yumuti wamazi wa 1% ni 6-8. Inzira ya molekuline ya HPMC ni C8H15O8- (C10H18O6) -C815O, naho misile igereranije ni 86.000.
HPMC ifite amazi meza cyane mumazi akonje. Irashobora gushonga mugisubizo kiboneye hamwe no gukurura gato mumazi akonje. Ibinyuranye, ahanini ntigishobora gushonga mumazi ashyushye hejuru ya 60 ℃ kandi irashobora kubyimba gusa. Nibintu bitari ionic selulose ether. Igisubizo cyacyo ntigishobora kwishyurwa ionic, ntigikorana numunyu wicyuma cyangwa ionic organic organic, kandi ntigikora nibindi bikoresho fatizo mugihe cyo gutegura; ifite imiterere ikomeye yo kurwanya allergique, kandi hamwe no kwiyongera kurwego rwo gusimbuza imiterere ya molekile, yayo Irwanya cyane allergie kandi ihamye; na inert metabolically inert. Nkimiti yimiti, ntabwo ihinduranya cyangwa ngo yinjizwe. Kubwibyo, ntabwo itanga karori mumiti nibiryo. Ni karori nkeya, idafite umunyu, kandi idafite umunyu kubarwayi ba diyabete. Imiti ya allergique nibiribwa bifite umwihariko udasanzwe; birasa neza kuri acide na alkalis, ariko niba agaciro ka PH karenze 2 ~ 11 kandi katewe nubushyuhe bwinshi cyangwa gifite igihe kirekire cyo kubika, ububobere bwacyo buzagabanuka; igisubizo cyacyo cyamazi kirashobora gutanga ibikorwa bya Surface, byerekana ubushyuhe buringaniye buringaniye hamwe nuburinganire bwimiterere; ifite emulisiyonike ikora muri sisitemu y'ibyiciro bibiri, irashobora gukoreshwa nka stabilisateur ikora neza kandi ikingira colloid; igisubizo cyamazi yacyo gifite imiterere myiza yo gukora firime, ni tablet na piline Ibikoresho byiza byo gutwikira. Ipitingi ya firime yakozwe nayo ifite ibyiza byo kutagira ibara no gukomera. Ongeramo glycerine irashobora kandi kunoza plastike yayo.
Ibicuruzwa bya QualiCell HPMC birashobora kunoza imitungo ikurikira muri Pharmaceutical Excipient:
· Iyo bimaze gushonga mumazi hanyuma bigahinduka binyuze mumashanyarazi, HPMC ikora firime ibonerana ifite imbaraga nyinshi.
· Kongera imbaraga zo guhuza.
Matrix ya Hydrophilique ikoreshwa hamwe na hydrata ya HPMC kugirango ikore geli, igenzura uburyo bwo kurekura ibiyobyabwenge.
| Tanga amanota: | Saba TDS |
| HPMC 60AX5 | Kanda hano |
| HPMC 60AX15 | Kanda hano |