Hydroxyprupyl methylcellose (HPMC) Icho chinowanzoshandisirwa mvura-yemvura-soluble polymer, inoshandiswa zvakanyanya mumishonga yemishonga, cosmetics, chikafu uye maindasitiri minda, kunyanya mukugadziriswa kwegweri. Zvivakwa zvaro zvepanyama uye maitiro ekupaza zvine hunhu hwakakosha pakubudirira mune dzakasiyana application. Iyo tembiricha yeHPMC Gel ndiyo imwe yenyaya yayo inokosha yemuviri, iyo inobata zvakananga mashandiro aro mukugadzirira kwakasiyana-siyana, sekusunungurwa, kuumbwa kwefirimu, kugadzikana, etc.
1. Chimiro uye zvivakwa zveHPMC
HPMC ndeye polymer yemvura yakawanikwa nekuunza maviri ezvikamu, hydroxypruppropyl uye methyl, mu cellulose molecular skeleton. Yayo moleky chimiro ine marudzi maviri ezvishandiso: hydroxyprupyl (-ch2chohch3) uye methyl (-ch3). Zvinhu zvakadai seyakasiyana hydroxpremyl zvemukati, degree remuimbi, uye degree rePolymerization ichave nemhedzisiro yakakosha pane iyo solubility, maitiro ehurume, uye michina yezvimiro zveHPMC.
Mumvura, shaceince®hpmc mafomu akaomeswa ekugadzirisa mari yekugadzira neHydrogen zvisungo nemamolekyudhi emvura uye kufambidzana neyechero cellenose-based skeleton. Kana nharaunda yekunze (yakadai sekupisa, ionic simba, nezvimwe) shanduko, kudyidzana pakati peHPMC mamorekuru kuchachinja, zvichikonzerwa negwenzi.
2. Tsanangudzo uye kufurira zvinhu zvekupisa geli
Kupisa kweGegul (tembiricha yekupisa, t_gel) inoreva tembiricha iyo iyo HPMC solution inotanga kushandurwa kubva kune yakasimba kana iyo mhinduro yekudzidzira inosimuka kune imwe tembiricha. Pane tembiricha iyi, kufamba kweHPMC molecular ketani kuchadzikiswa, kuumba matatu-matatu-dimensice network chimiro, zvichikonzera chinhu cheGel-sepfuma.
Iyo tembiricha yeiyo hpmc inokanganiswa nezvinhu zvakawanda, chimwe chezvinhu zvakakosha ndizvo zvehydroxpropropropyl. Pamusoro peiyo hydroxyprusyl yezvinyorwa, zvimwe zvinhu zvinokanganisa tembiricha yeGel inosanganisira surure uremu, mhinduro yekusimbisa, ph kukosha, solvent mhando, ionic simba, nezvimwe.
3. Mhedzisiro yehydroxypropyl zvemukati paHPMC Gel tembiricha
3.1 Kuwedzera kwehydroxyprishipropyl zvirimo kunotungamira kune kuwedzera kwekushisa kweGel tembiricha
Iyo tembiricha yeiyo hpmc yakanyatsoenderana neiyo degree re hydroxyprupylxpressl substitution mumorekuru kwayo. Sezvo hydroxyprupropyl yezvinyorwa zvinowedzera, nhamba yeiyo hydrophilic yekutsiva pane iyo HPMC molecular keteni inowedzera, zvichikonzera kuwedzerwa kwekudyidzana pakati pemamoreni nemvura. Uku kudyidzana kunokonzeresa maketani ekunyomba kutambanudza mberi, nekudaro kuderedza simba rekudyidzana pakati pemaketani emanyorerwo. Mukati meimwe nzvimbo yekuvharirwa, ichiwedzera iyo hydroxyprusyl zvemukati inobatsira kusimudzira iyo degree re hydration uye inosimudzira gadziriro yemanyorerwo emanyorerwo, kuitira kuti chimiro chine netiweki chinogona kuumbwa pakupisa kwakanyanya. Naizvozvo, tembiricha yemhepo inowedzera nehydroxyprupyl inosimuka nekuwedzera zvirimo.
HPMC ine yakakwira hydroxyprupyl zvirimo (senge HPMC K15m) inowanzo kuratidzira tembiricha yakakwira pane imwe nzvimbo yekusagadzikana Izvi zvinodaro nekuti yepamusoro hydroxpremyl zvemukati zvinoita kuti zviwedzere kufambidzana uye kuumba tembiricha yekupisa, inoda kupisa uku uye kusimudzira kuyamadza kuumbwa kuumba matatu-matatu emhando network chimiro. .
3.2 hukama pakati pehydroxyprupropyl zvemukati uye mhinduro yekusangana
Solution yekugadzirisa zvakare chinhu chakakosha chinokanganisa tembiricha yehipmc. Mukupindirana kwepamusoro HPMC mhinduro, kushamwaridzana kwekushanda kwakasimba, saka tembiricha yegungwa inogona kunge yakakwira kunyangwe iyo hydroxpropropyl zvemukati zvakadzika. Pakutenderera zvakaderera, kudyidzana pakati peHPMC mamorekuru hakuna kusimba, uye mhinduro yacho ichingokwanisika kujekesa pakadzika.
Kana iyo hydroxyprupropyl yemukati inowedzera, kunyangwe iyo hydrophilikuity inowedzera, tembiricha yakakwira ichiri kudiwa kuti iite gel. Kunyanya pasi pemamiriro ekushongedza madiki, tembiru yemhepo inowedzera zvakanyanya. Izvi zvinodaro nekuti HPMC ine HYDROPPROPPROPLL zvemukati zvakanyanyisa kuoma kuti zvinyorwe kutaurirana pakati pemachira ekushambadzira, uye maitiro egungwa anoda mamwe simba rekuwedzera kukurira hydration.
3.3 Mhedzisiro yehydroxyprupropyl zvemukati paGenational Process
Mukati meimwe huwandu hwe hydroxyprupropropyl, maitiro egwenga anotongwa nekudyidzana pakati pehydration uye majaya. Kana iyo hydroxyprupropyl yezvinyorwa muHPMC molecule yakaderera, hydration haina kusimba, kutaurirana pakati pemamorekuru kwakasimba, uye tembiricha yakadzika inogona kusimudzira kuumbwa kwegwenzi reGel. Kana iyo hydroxyprupropropyl yezvinyorwa, hydration yakakurudzirwa zvakanyanya, kudyidzana pakati pemachira emanyorose kunova kushaya simba, uye kupisa kwegwenga kunowedzera.
Yakakwira HydroxyPropyl Zvemukati zvinogona kutungamirawo kune kuwedzera kweiyo viscosity yeHPMC solution, shanduko iyo dzimwe nguva inowedzera tembiricha yekuisa yegwenzi.
Hydroxyprupropyl zvemukati zvine hunhu hwakakosha pane kupisa kwegungwa kweHpc. Sezvo iyo hydroxyprupropyl yezvemukati inowedzera, iyo hydrophilipity yeHPMC inowedzera uye kuwirirana pakati pemanyorerwo emaketani anonetsekana, saka tembiricha yayo inowanzowedzera. Ichi chiitiko chinogona kutsanangurwa neyekudyidzana muchimiro pakati pehydration uye majaya. Nekugadzirisa iyo hydroxyprupyl zvemukati yeHPMC, kudzora kweiyo denderedzwa tembiricha kunogona kuwanikwa, nekudaro optimizing kuitwa kweHPMC mune mishonga, chikafu uye zvimwe zvekushandisa maindasitiri.
Kutumira Nguva: Jan-04-2025