Hydroxypropylmethylcylosellose (HPMC) iri nzvimbo iyo yave iri nzvimbo yechigaro chechigadzirwa mune akawanda maindasitiri nekuda kwenzvimbo dzayo dzakawanda. Zvinowanzoshandiswa sechikafu chinowedzera, chinese mumazino, uye kunyange chinongedzo mumishonga yakawanda. Iyo yakasarudzika midziyo yeHPMC ndeye iyo thk Uye zvakare, zvese zvakakwirira-viscosity uye low-vcosity HPMC ine ichi chivakwa, kuratidzira thisiotropy kunyangwe pazasi pegomba tembiricha.
The thiskotropy inoitika muHPMC kana mhinduro yava sheerera kana kudzvinyirira kuchishandiswa kana kumutswa, kukonzera kuderera kweViscosity. Maitiro aya anogona zvakare kudzoserwa; Kana kushushikana kwabviswa uye mhinduro yasara kuzorora, iyo viscosity zvishoma nezvishoma inodzokera kunzvimbo yayo yepamusoro. Iyi yakasarudzika midziyo inoita HPMC chinhu chakakosha muindasitiri akawanda sezvo ichibvumira kuti ishandiswe applicet uye iri nyore kugadzirisa.
Senge hynionic hydrocolloid, Hpmc canlls mumvura kuti iite gel. Dhigirii rekuzvimba uye gomba rinoenderana nehuremu hwemanyorerwe uye kusvinura kwePolymer, iyo pH uye tembiricha yemhinduro. Yakakwira viscosity HPMC inowanzove neyekumusoro srewlar uremu uye inogadzira yakakura viscosity gel, nepo yakaderera viscosity HPMC ine yakaderera molecular uremu uye inoburitsa mashoma viscous gl. Nekudaro, kunyangwe paine misiyano iyi mukuita, marudzi ese eHPMS exhibit thixotropy nekuda kwekushandurwa kwechimiro chinoitika padanho remufaro.
Iyo yeTXotropic maitiro eHPMC ndeyekuenderana nekuenderana kwemaketeni emapolymer nekuda kwekushushikana. Kana shear isingashandiswi kuHPMC, mafungu ePolymy anoenderana nekushushikana kwekushandiswa kwekushandiswa, zvichikonzera kuparadzwa kweiyo nhaurwa dzematanho matatu akagadzirwa network yakarongedzwa mukushaikwa kwekushushikana. Kuvhiringidza kwetiweki kunoguma nekuderera kwemhinduro yekugadzirisa. Kana kushushikana kwabviswa, ngetani dzemapolitani dzinodzoreredza parwendo rwavo rwekutanga, kuvaka zvakare network uye kudzoreredza viscosity.
HPMC zvakare inoratidzira iyo thiskropy pazasi pekushambadzira kwekushisa. Iyo tembiricha yekudziya ndiyo tembiricha iyo polymer cheni yekuyambuka-chinongedzo kuti iite matatu-dimensional network, kugadzira gel. Zvinoenderana nesangano rekusangana, suremu hwemanyorerwe uye pH yemhinduro yePolymer. GELLATTING YAKAITWA ine vhiza yakakwira uye haichinje nekukurumidza pasi pekumanikidzwa. Nekudaro, pazasi peiyo tembiricha yemakomo, iyo HPMC mhinduro yakaramba yakasviba, asi ichiri kuratidzwa maitiro eiyo nekuda kwekuvapo kwechimiro chakaumbwa network. Network yakaumbwa nezvidimbu izvi inopaza pasi pekumanikidzwa, zvichikonzera kuderera kwemisangano. Uyu maitiro anobatsira mune akawanda mashandisiro aunoita mhinduro dzinoda kuyerera nyore nyore kana rimurwa.
HPMC chinhu chemaketi mese neye akati wandei akasiyana midziyo, imwe yacho ndeye thisicucropic maitiro. Vese vakakwira-viscosity uye vakaderera-viscosity hpmc vane ichi chivakwa, kuratidzira thiskotropy kunyangwe pazasi pegomba tembiricha. Hunhu uhwu hunoita hpmc chinhu chakakosha muindasitiri mazhinji anoda mhinduro dzinobata nyore nyore kuyerera kuve nechokwadi chekushandisa. Pasinei nemusiyano mune zvivakwa pakati pehukuru-viscosity uye yakaderera-viscosity hpmcs, maitiro avo ehukisheni anoitika nekuda kwekuenderana uye kukanganisa kweiyo yakaumbwa network yakarongedzwa network. Nekuda kwezvinhu zvaro zvakasarudzika, vaongorori vanogara vachiongorora zvakasiyana siyana zveHPMC, vachitarisira kugadzira zvigadzirwa zvitsva uye kupa mhinduro dziri nani kune vatengi pasi rese.
Kutumira Nguva: Aug-23-2023