HPMC (hydroxyprEpropyl methylcellose) inzvimbo yakashata yemvura inoshandiswa zvakanyanya muminda yekuvaka, mishonga yemishonga, chikafu nemazuva ese. Iyo ine yakanaka kuremerwa, emulsificing, firimu-inoumba, inodzivirira collid uye zvimwe zvinhu. Mune emulsion masisitimu, HPMC inogona kudzora zvevasikidzo ye emulsion nenzira dzakasiyana siyana.
1. Molecular chimiro cheHPMC
Iyo viscosity yeHPMC inonyanya kukanganiswa neyakaomeswa nehuremu uye degree rekutsiva. Iyo yakakura uremu hwemanyorerwe, yakakwira iyo visikopa yemhinduro; uye degree rekutsiva (iro riripo rekutsiva kwehydroxypropropyl uye mapoka mapoka) anokanganisa iyo solubility uye viscosity zvivakwa zveHPMC. Kunyanya, iyo yakakwira iyo degree rekutsiva, zviri nani iyo solubil yemvura yeHPMC, uye visikoka inowedzera saizvozvo. Vagadziri vanowanzopa zvigadzirwa zveHPMC nemakiromita akasiyana uye madhigiri ekutsiva kuzosangana nezvinodiwa zvekushandisa zvakasiyana.
2. Shandisa kusimbisa
Iko kusimbiswa kweHPMC mumamiriro ekunze ndiyo imwe yezvinhu zvakakosha zvinokanganisa zvevishu. Kazhinji, iyo yepamusoro yekuvhara kweHPMC, iyo yakakura zvevisiko zvemhinduro. Nekudaro, iyo viscosity yemhando dzakasiyana dzeHPMC pane imwecheteyo yekuvhara inogona kusiyana zvakanyanya. Naizvozvo, mune zvinoshanda zvinoshandiswa, zvinodikanwa kusarudza kusarudzika kwakakodzera kweHPMC solution zvichienderana nezvinodiwa zvevascosity. Semuenzaniso, mune zvekuvaka ma-hpmc inowanzo kudzorwa pakati pe0.1% uye 1% kupa yakakodzera yekushanda viscosity uye kuita zvekuvaka.
3. Dissolution nzira
Maitiro ekunyungudutswa eHPMC zvakare ane chakakosha kukanganisa pane yekupedzisira viscosity. HPMC iri nyore kuparadzira mumvura inotonhora, asi iyo yekunyungudika inononoka; Inopaza nekukurumidza mumvura inopisa, asi zviri nyore kuti uwedzere. Kuti udzivise Agglomeration, iyo nzira yekuwedzera yekuwedzera inogona kushandiswa, kureva kuti, kutanga zvishoma nezvishoma Mukuwedzera, HPMC inogona zvakare kuve yakavezwa nedzimwe yakaomeswa podals uye yakazowedzerwa kumvura kuti isimbe kuti uvandudze kunyatsoita kwekunyora uye viscossity kugadzikana.
4. Tembiricha
Tembiricha ine kukosha kwakanyanya pane viscosity yeHPMC mhinduro. Muzhinji, iyo viscosity yeHPMC mhinduro inoderera sezvo tembiricha inowedzera. Izvi zvinodaro nekuti kupisa kupisa kwehydrogen kusungwa pakati pemamorekuru, kugadzira iyo HPMC molecular keteni inotsvedza, nekudaro ichidzora mavheti eiyo mhinduro. Naizvozvo, mune zvekushandisa zvinoda kwazvo viscossity, HPMC mhinduro dzinowanzoshandiswa pakudziya kwakadzika. Semuenzaniso, mune mishonga yekushandisa, HPMC mhinduro dzinowanzo shandiswa pamhepo tembiricha kuti ive nechokwadi chekugadzikana uye kushanda kwemushonga.
5. PH Kukosha
Iyo viscosity yeHPMC Solution inokanganiswawo nePP kukosha. HPMC ine iyo yepamusoro viscosity pasi pemamiriro ekunze uye isina kusimba acidic mamiriro, nepo viscosity ichadzikira zvakanyanya pasi pemamiriro ezvinhu akasimba kana alkaline mamiriro. Izvi zvinodaro nekuti zvakanyanyisa ph kukosha zvinoparadza iyo molecular chimiro cheHPMC uye inokanganisa simba rayo rakashata. Naizvozvo, mune zvinoshanda zvikumbiro, iyo pH Kukosha kweiyo inoda kudzorwa uye kuchengetwa mukati meiyo nzvimbo yakagadzikana yeHPMC (kazhinji pH 3-11) kuti ive nechokwadi chekuita kwayo. Semuenzaniso, mune zvekudya zvekudya, HPMC inowanzo shandiswa mune yezvikafu zvekudya senge yogirt neiyo muto, uye iyo yakanakisa viscosity inogona kuwanikwa nekugadzirisa iyo pH kukosha.
6. Zvimwe zvinowedzera
Mune emulsion masisitimu, iyo viscosity yeHPMC inogona zvakare kugadziridzwa nekuwedzera mamwe manhamba kana sol sol. Semuenzaniso, kuwedzera huwandu hwakakodzera hwemasorgic salts (senge sodium chloride) inogona kuwedzera iyo visikopa yeHPMC solution; Paunenge uchiwedzera organic sol sol sol solen ethanol inogona kuderedza zvavakaita. Uye zvakare, kana ichishandiswa mukubatanidzwa pamwe nedzimwe nhambo (dzakadai sa xanthan gamu, carbomer, etcoss, etcosity uye kugadzikana kwemhedzisiro inogona zvakare kuve yakagadziridzwa zvakanyanya. Naizvozvo, mune chaiyo formula dhizaini, zvakakodzera zvekuwedzera zvinogona kusarudzwa sezviri kudikanwa kuti uwedzere kuongorora zvevasokisi uye kuita kwe emulsion.
HPMC inogona kuwana chaiyo kudzora kwe emulsion viscosity kuburikidza neiyo molecular chimiro, kusimbisa kusimbisa, nyonganiso nzira, tembiricha, ph kukosha uye yekuwedzera. Mune zvinoshanda zvinoshanda, izvi zvinhu zvinoda kufungidzirwa kuti zvinyatso sarudza yakakodzera HPMC mhando uye yekushandisa mamiriro ezvinhu kuti uwane iyo yakakodzera yakakodzera mhedzisiro. Kuburikidza neyesainzi Formula Dhizaini uye HPMC inogona kutamba yakakosha basa rakakosha mumunda wekuvaka, mishonga yemishonga, chikafu nemazuva ese emakemikari, kupa ruzivo rwekuita uye mushandisi.
Kutumira Nguva: Jul-17-2024