Hydroxyethyl cellulosechinhu chakakosha cellulose derivative. Nekuda kwemabhenefiti ezvakawanda zviwanikwa zvezviwanikwa, zvinodzoreredzwa, biodegradable, isiri-chepfu, yakanaka biocompatibility, uye goho rakakura, kutsvagisa kwayo uye kushandisa kwakwezva kutarisisa. . Viscosity kukosha ndiyo yakakosha kuita index yehydroxyethyl cellulose. Mupepa iri, hydroxyethyl cellulose ine viscosity kukosha pamusoro pe5 × 104mPa · uye kukosha kwemadota isingasviki 0.3% yakagadzirirwa ne-liquid-phase synthesis nzira kuburikidza nealkalization uye etherification maviri-nhanho maitiro.
Iyo alkalization process ndiyo nzira yekugadzirira yealkali cellulose. Mupepa iri, nzira mbiri dze alkalization dzinoshandiswa. Nzira yekutanga ndeyokushandisa acetone semushonga. Iyo cellulose raw material yakavakirwa zvakananga mune imwe denderedzwa ye sodium hydroxide aqueous solution. Mushure meiyo basification reaction yaitwa, etherifying agent inowedzerwa kuti iite zvakananga etherification reaction. Yechipiri nzira ndeyokuti cellulose mbishi zvinhu inoiswa alkali mumushonga une aqueous wesodium hydroxide uye urea, uye alkali cellulose yakagadzirwa neiyi nzira inofanirwa kusvinwa kuti ibvise lye yakawandisa isati yaitika etherification. Iyo alkali cellulose yakagadzirwa nenzira dzakasiyana yakaongororwa ne infrared spectroscopy uye X-ray diffraction. Zvinoenderana nehunhu hwezvigadzirwa zvakagadzirirwa ne etherification reaction, nzira yekusarudza inotarwa.
Kuti uone yakanakisa etherification synthesis process, maitiro ekuita zve antioxidant, lye uye glacial acetic acid mune etherification reaction yakatanga kuongororwa. Wobva wagadzira chirongwa chekuyedza che single factor reaction, tarisa zvinhu zvine chekuita zvakanyanya pakuita kweyakagadzirirwa hydroxyethyl cellulose, uye shandisa viscosity yechigadzirwa che 2% aqueous solution sereferensi index. Mhedzisiro yekuedza inoratidza kuti zvinhu zvakaita seyakasarudzwa diluent chiyero, huwandu hweethylene oxide yakawedzerwa, nguva yealkalization, tembiricha uye nguva yekutanga kuita, tembiricha uye nguva yechiitiko chechipiri zvese zvine simba guru pakuita kwekuita. chigadzirwa. Orthogonal test scheme ine zvinhu zvinomwe uye mazinga matatu akadhirowewa kumusoro, uye mhedzisiro curve yakatorwa kubva muyedzo mhinduro inogona nekuona yepakutanga uye yechipiri zvinhu uye pesvedzero yechinhu chimwe nechimwe. Kuti ugadzirire zvigadzirwa zvine yakakwirira viscosity kukosha, yakagadziridzwa yekuyedza chirongwa chakagadzirwa, uye iyo yakakwana chirongwa chekugadzirira hydroxyethyl cellulose yakazotemerwa kuburikidza nemhedzisiro yekuedzwa.
Zvinhu zvezvakagadzirirwa high-viscosityhydroxyethyl celluloseakaongororwa uye akaedzwa, kusanganisira kuomerwa kweviscosity, madota emukati, mwenje transmittance, hunyoro hwemukati, nezvimwewo, kuburikidza ne infrared spectroscopy, nuclear magnetic resonance, gas chromatography, X-ray diffraction, Thermogravimetric-differential thermal analysis uye dzimwe nzira dzemhando dzinoshandiswa. kuongorora uye kuratidza chimiro chechigadzirwa, chinotsiva kufanana, molar substitution degree, crystallinity, thermal stability, etc. Nzira dzekuedza dzinoreva ASTM zviyero.
Hydroxyethyl cellulose, yakakosha cellulose derivative, yakwezva kutarisisa nekuda kwekuwanda kwayo zviwanikwa zvekushandisa, zvinogonekazve, zvinoparara, zvisingaite, biocompatible, uye goho repamusoro. Iyo viscosity yehydroxyethyl cellulose chiratidzo chakakosha chekuita kwayo. Iyo viscosity yeyakagadzirirwa hydroxyethyl cellulose iri pamusoro pe5 × 104mPa · s, uye madota ari pasi pe0.3%.
Mune pepa iri, yakakwira-viscosity hydroxyethyl cellulose yakagadzirwa ne-liquid-phase synthesis nzira kuburikidza nealkalization uye etherification. Iyo alkalization process ndeye kugadzirira kwe alkali cellulose. Sarudza kubva kune maviri alkalization nzira. Imwe ndeyekuti iyo cellulose zvinhu inonatswa alkalized neacetone se diluent mune aqueous sodium hydroxide solution, yobva yaitwa etherification reaction ne etherifying agent. Imwe yacho ndeyekuti iyo cellulosic zvinhu inogadziriswa mune aqueous sodium hydroxide solution uye urea. Iyo yakawandisa alkali mu alkali cellulose inofanira kubviswa isati yaita. Mupepa iri, akasiyana alkali cellulose anodzidzwa ne infrared spectroscopy uye X-ray diffraction. Pakupedzisira, nzira yechipiri inogamuchirwa zvinoenderana nemidziyo ye etherification zvigadzirwa.
Kuti uone matanho ekugadzirira etherification, maitiro ekuita kwe antioxidant, alkali uye glacial acetic acid mukudya kwakadzidzwa. Izvo zvinhu zvinokanganisa kugadzirira kwehydroxyethyl cellulose zvakatemerwa nechinhu chimwe chete kuyedza. Kubva pane viscosity kukosha kwechigadzirwa mu 2% aqueous solution. Mhedzisiro yekuedza inoratidza kuti vhoriyamu ye diluent, huwandu hwe ethylene oxide, iyo alkalization nguva, tembiricha uye nguva yekutanga neyechipiri rehydration zvine simba guru pakuita kwechigadzirwa. Nzira yezvinhu zvinomwe uye matanho matatu akagamuchirwa kuti aone nzira yakanakisisa yekugadzirira.
Isu tinoongorora maitiro ezvakagadzirirwahydroxyethyl cellulose, kusanganisira viscosity, madota, chiedza transmittance, mwando, etc. The structural characterization, substituent homogeneity, substitution molarity, crystallinity uye thermal kugadzikana zvakakurukurwa ne infrared, nuclear magnetic resonance, gas chromatography, X-ray diffraction, DSC uye DAT, uye nzira dzekuyedza dzakagamuchirwa zviyero zveASTM.
Nguva yekutumira: Kubvumbi-25-2024