Hypromllose yakagadzirwa sei?

Hypromellose, anozivikanwa se hydroxyprupyl methylcellose (HPMC), is simisynthetolet polymer yakawanikwa kubva ku cellulose, chiitiko chomuzvarirwo zvinoitika chakawanikwa mumaruva emusikana. Iko kugadzirwa kwehypromellose kunosanganisira matanho akati wandei, kusanganisira kuwedzerwa uye kucheneswa. Heano kutarisisa kwehunhu hwakaitwa hypomelose.

1. Cellulose Sourcing: Maitiro acho anotanga neCellincing Cellalose, iyo inogona kuwanikwa kubva kune dzakasiyana siyana zvirimwa zvakaita sehuni dzehuni, machira emakotoni, kana zvimwe zvidyarwa. Cellulose inowanzo kubviswa kubva kune izvi zvinyorwa kuburikidza neyekutevedzana kwemakemikari uye maitiro maitiro kuti uwane iyo yakacheneswa cellulose zvinyorwa.
2. Kuwedzera: Iyo yakanatswa cellulose inoisa nzira yemakemikari inodaidzwa kuti eritiyation, uko hydroxyprospropyl uye methyl mapoka anounzwa kuCellulose Backbone. Uku kugadziridzwa kunowanikwa nekuita cellulose nePropylene oxide (kuunza hydroxypropyl mapoka) uye methyl chloride (yekuunza methyl mapoka) pasi pemamiriro ezvinhu anodzorwa.
3. Kuchenesa: Mushure mekushatirwa, chigadzirwa chinobva chave kucheneswa kuti ubvise kusvibiswa uye ne-zvigadzirwa kubva pakuita. Izvi zvinogona kusanganisira kushambidza, filtration, uye dzimwe nzira dzekuparadzanisa kuti dziwane kuchena hypomelose chigadzirwa.
4. Kuomesa uye kugaya: Iyo yakacheneswa hyprollose inozoomeswa kuti ibvise yakanyanyisa kunyorova uye yakanyorwa muhuku yakanaka kana granules. Iyo size size uye morphology yeiyo hypromllose poda inogona kudzorwa kuti isangane zvakananga zvinodiwa kuti zviitike zvakasiyana.
5. Kudzora Kwemhando: Muzviitiko zvese zvekugadzira, matanho ekudzora emhando anoitwa kuti ave nechokwadi chekuchena, kusawirirana, uye kushanda kweiyo hyplompomelose chigadzirwa. Izvi zvinosanganisira kuyedzwa kwerapeter yakadai seyekuita suremu, viscosity, solubility, uye zvimwe zvinhu zvemuviri uye zvemakemikari.
6. Kuiswa uye kugovera: Kamwe hypromllose chigadzirwa chinosangana nemidziyo yemhando uye yakagoverwa kune dzakasiyana-siyana maindasitiri ekushandisa mumishonga, zvigadzirwa, zvigadzirwa, uye zvimwe zvinoshandiswa.

Zvakawanda, kugadzirwa kwehypromellose kunosanganisira kutevedzana kwemakemikari ekudzora uye kucheneswa kwekunyora kushandisirwa makomendi, zvichikonzera polymerile uye yakashandiswa zvakanyanya polymer ine maindasitiri akasiyana siyana mumaindasitiri akasiyana siyana.