(1) Nhanganyaya kuHPMC
Hydroxypropyl Methylcellulose (HPMC) yakakosha nonionic cellulose ether inoshandiswa zvakanyanya mu detergents, zvekuvaka, chikafu, mishonga nemimwe minda. Muchigero chekugezesa, HPMC inoshandiswa seyakakora kuti ipe yakanakisa kumiswa kugadzikana uye kunyungudika, inosimudzira kunamatira uye kugeza mhedzisiro yewachisi yekuwachira. Nekudaro, kuti uwane iyo yakakwana viscosity yeHPMC mune yekuwachira detergent, zvinhu zvakawanda zvinoda kutariswa, kusanganisira mhando, dosi, mamiriro ekuparara, kutevedzana kwekuwedzera, nezvimwe zveHPMC.
(2) Zvinhu zvinokanganisa HPMC viscosity
1. Mhando uye mhando dzeHPMC
Huremu hwemamorekuru uye dhigirii rekutsiva (methoxy uye hydroxypropyl substitution) yeHPMC inokanganisa zvakananga viscosity yayo uye solubility zvivakwa. Mhando dzakasiyana dzeHPMC dzine akasiyana viscosity siyana. Kusarudza HPMC modhi inokodzera yako yekuwachira detergent zvinodiwa kwakakosha. Kazhinji kutaura, epamusoro mamorekuru uremu HPMCs inopa yakakwira viscosities, nepo yakaderera molecular uremu HPMCs inopa yakaderera viscosities.
2. Dosage yeHPMC
Huwandu hweHPMC hune mhedzisiro yakakosha pane viscosity. Kazhinji, HPMC inowedzerwa muhuwandu huri pakati pe0.5% ne2% mune zvekusuka mbatya. Iyo dosage yakadzikira haigone kuwana yaunoda kukora mhedzisiro, nepo dosage yakawandisa inogona kutungamira kumatambudziko akadai sekuomerwa mukunyungudika uye kusaenzana kusanganisa. Naizvozvo, iyo dosi yeHPMC inoda kugadziridzwa zvinoenderana nezvinodiwa chaizvo uye mhedzisiro yekuyedza kuti uwane yakakwana viscosity.
3. Dissolution mamiriro
Mamiriro ekuparara kweHPMC (tembiricha, pH kukosha, kumhanyisa kumhanya, nezvimwewo) zvine chekuita kwakakosha pakuona kwayo:
Tembiricha: HPMC inonyungudika zvishoma nezvishoma pane tembiricha yakaderera asi inogona kupa yakakwira viscosities. Inonyungudika nekukurumidza pakudziya kwakanyanya asi ine yakaderera viscosity. Inokurudzirwa kunyungudutsa HPMC pakati pe20-40 ° C kuti ive nechokwadi chekugadzikana kwayo uye viscosity.
pH: HPMC inoita zvakanyanya pasi pemamiriro asina kwaakarerekera. Yakanyanya pH kukosha (yakanyanya acidic kana yakanyanya alkaline) inogona kuparadza chimiro cheHPMC uye kuderedza viscosity yayo. Naizvozvo, kudzora iyo pH kukosha kweiyo yekuwachira detergent system pakati pe6-8 inobatsira kuchengetedza kugadzikana uye viscosity yeHPMC.
Kumhanyisa kumhanya: Yakakodzera yekumhanyisa kumhanya inogona kusimudzira kuparara kweHPMC, asi kunyandura zvakanyanya kunogona kuunza mabhubhu uye kukanganisa kufanana kwemhinduro. Zvinowanzo kurudzirwa kushandisa inononoka uye inomhanyisa kumhanya kunyungudutsa zvizere HPMC.
4. Wedzera kurongeka
HPMC inoumba nyore agglomerates mune mhinduro, inokanganisa kuparara kwayo uye viscosity kuita. Naizvozvo, kurongeka uko HPMC inowedzerwa kwakakosha:
Pre-mixing: Sanganisa HPMC nemamwe hupfu hwakaoma zvakaenzana uye wozowedzera zvishoma nezvishoma kumvura, izvo zvinogona kudzivirira kuumbwa kwezviputi uye kubatsira kunyungudika zvakaenzana.
Kunyorovesa: Usati wawedzera HPMC kumushonga wekusuka mbatya, unogona kutanga wanyorovesa nemvura shoma inotonhora, wozowedzera mvura inopisa kuti uinyunguduse. Izvi zvinogona kuvandudza kugona kwekuparara uye viscosity yeHPMC.
(3) Matanho ekugadzirisa HPMC viscosity
1. Formula design
Sarudza iyo yakakodzera HPMC modhi uye dosi zvichibva pakupera kwekushandisa uye zvinodiwa zvekuchenesa mbatya. Yakanyanya-kunyatso kuchenesa mbatya dzekugezesa ingada yakakwira viscosity HPMC, nepo zvigadzirwa zvekuchenesa zvakajairika zvingasarudza zvepakati kusvika kuzasi viscosity HPMC.
2. Kuedza kuedza
Ita madiki-batch bvunzo murabhoritari kuti utarise maitiro ayo pane viscosity yekuchenesa hembe nekushandura dosage, dissolution mamiriro, kuwedzera kurongeka, nezvimwe zveHPMC. Rekodha maparamendi uye mhedzisiro yekuyedza yega yega kuti uone yakanakisa musanganiswa.
3. Kugadziriswa kwemaitiro
Isa mabikirwo emurabhoritari akanakisa uye mamiriro ekugadzirisa kumutsara wekugadzira uye uzvigadzirise kuti ugadzire hukuru. Ita shuwa kugovera yunifomu uye kuparara kweHPMC panguva yekugadzira nzira kudzivirira matambudziko akadai senge clumps uye kusaparara kwakashata.
4. Kudzora kwehutano
Kuburikidza nemhando dzekuyedza nzira, senge viscometer kuyerwa, particle saizi yekuongorora, nezvimwewo, kuita kweHPMC mune yekuwachira detergent inotariswa kuti ive nechokwadi chekuti inowana viscosity inotarisirwa uye mashandisiro ekushandisa. Ita ongororo dzemhando yepamusoro uye nekukasira gadzirisa maitiro uye mafomula kana matambudziko awanikwa.
(4) Mibvunzo inowanzo bvunzwa uye mhinduro
1. Kuparara kusina kunaka kweHPMC
Zvikonzero: Tembiricha isina kufanira yekunyungudika, kukurumidza kana kunonoka kumhanyisa kumhanya, kurongeka kwakashata, nezvimwe.
Kugadzirisa: Gadzirisa tembiricha yekunyungudika kusvika 20-40 ° C, shandisa inononoka uye inomhanyisa kumhanya, uye gadzirisa kutevedzana kwekuwedzera.
2. HPMC viscosity haisi kusvika pachiyero
Zvikonzero: Iyo HPMC modhi haina kufanira, iyo dosage haina kukwana, iyo pH kukosha yakanyanya kana kuderera, nezvimwe.
Solution: Sarudza yakakodzera HPMC modhi uye chipimo chemushonga, uye kudzora iyo pH kukosha kweiyo yekuwachisa dhizaini system pakati pe6-8.
3. HPMC clump kuumbwa
Chikonzero: HPMC yakawedzerwa zvakananga mumhinduro, zvisizvo kuparara mamiriro, nezvimwe.
Solution: Shandisa pre-kusanganisa nzira, tanga sanganisa HPMC nemamwe hupfu yakaoma, uye zvishoma nezvishoma wowedzera kumvura kunyunguduka.
Kuti uwane iyo yakakwana viscosity yeHPMC mune yekuwachira detergent, zvinhu zvakaita serudzi, dosi, mamiriro ekuparara, uye kurongeka kwekuwedzera kweHPMC kunoda kutariswa zvizere. Kuburikidza nesainzi fomula dhizaini, kuyedza kuyedza uye kugadzirisa maitiro, iyo viscosity mashandiro eHPMC inogona kunyatsogadziriswa, nekudaro ichivandudza mashandisiro ekushandisa uye kukwikwidza kwemusika kwekuchenesa mbatya.
Nguva yekutumira: Jul-08-2024