Kuvhiringidza HydroxyPropyl methylcellose (HPMC) mumvura muitiro wakajairika muindasiti dzakasiyana-siyana, kusanganisira mishonga yemishonga, chikafu, zvidyarwa, uye kuvaka. HPMC ndeye cellulose inobviswa inoumba pachena, isina ruvara, uye viscous mhinduro kana yakasanganiswa nemvura. Mhinduro iyi inoratidza zvivakwa zvakasarudzika sekuremerwa, kusunga, kusunga-kuumba, uye kusunungurwa kwekusunungurwa kwezvinhu zvinoshanda. Maitiro ekunyungudutswa eHPMC mumvura anosanganisira matanho akakodzera kuti ave nechokwadi chekupararira kwayo uye kufanana.
Nhanganyaya yeHPMC:
HydroxyPropyl methylcellose (HPMC) ndeye isiri-ionic cellulose ether inotorwa kubva kune yakasikwa polymer cellulose. Iyo yakashongedzwa nekurapa cellulose ine profilyone oxide uye methyl chloride. HPMC inoshandiswa zvakanyanya muindasitiri akasiyana siyana nekuda kweiyo yakanaka firimu-inoumba, kurerutsa, kusimbisa, uye kwemvura-kudzokorora zvivakwa. Zvekutanga zvekushandisa HPMC zvinosanganisira:
Pharmaceutals: Inoshandiswa seye binder, firimu yaimbova, viscosity modifier, uye yakadzorwa-kuburitsa mumiriri mumapiritsi, makapindu, mafuta, uye kumiswa.
Indasitiri yeChikafu: Inoshandiswa sedhizaini, stabilizer, emulsififier, uye kunyorovesa mumiririri mune zvigadzirwa zvekudya senge sosi, madhiri, uye zvakabikwa zvinhu.
Kuvaka: Zviito seMumiriri wevanhu-Wemvura, Kunamatira, uye kwakasimba pamasimendi-based-based malasters, magirazi eGypsum anobva, uye magetsi anonamira.
Cosmetics: Mabasa sekambani, yefirimu aimbova, uye emulsion stabilizer mumakiromita, shampoos, uye zvigadzirwa zvekutarisira pachako.
Dissolution maitiro eHPMC mumvura:
Kuzeya HPMC mumvura kunosanganisira matanho anokosha anoverengeka kuti uwane yunifomu uye yakagadzikana mhinduro:
Kusarudzwa kweHPMC Giredhi: Sarudza giredhi rakakodzera reHPMC zvichibva pane yaunoda viscosity, chidimbu chevhu, uye chinhanho chekutsiva. Mamakisi akasiyana anopa madhigirii akasiyana eViscosity uye Solubility maitiro.
Kugadzirira kwemvura: Shandisa yakacheneswa kana yakanatswa mvura kugadzirira mhinduro. Hunhu hwemvura hunogona kukanganisa zvakanyanya maitiro ekunyungudza uye zvinhu zvemhinduro yekupedzisira. Ngwarira kushandisa mvura yakaoma kana mvura ine tsvina inogona kukanganisa njodzi.
Kuremha uye kuyera: kuyera nenzira kwayo huwandu hunodiwa hweHPMC uchishandisa digital chiyero. Iyo yakakurudzirwa yekuvharirwa yeHPMC mumvura inosiyana zvichienderana nechinangwa chekushandisa. Kazhinji, kutarisisa kubva ku0,1% kusvika ku5% w / W zvakajairika kune mazhinji maapplication.
Hydration Stage: Sasa iyo yakayerwa HPMC zvishoma nezvishoma uye zvakaringana pamusoro pemvura uchimutsa nguva dzose. Ngwarira kuwedzera HPMC mumatanho makuru ekudzivirira kuumbwa kwemapundu kana aglomeromer. Bvumira iyo HPMC kuti iite uye kuparadzira zvishoma nezvishoma mumvura.
Kusanganisa uye kusanganisa Chengetedza zvinyoro nyoro kudzivisa zvakawandisa kupupuma kana kumhanyisa kwemhepo.
Tembiricha Control: Tarisa uye kudzora tembiricha panguva yekudzvinyirira. Muzviitiko zvakawanda, tembiricha yemakamuri (20-25 ° C) yakwana kupaza hpmc. Nekudaro, zvekukurumidza kushungurudzika kana chimiro chaicho, kukwidziridzwa kwakakwirira kunogona kudiwa. Ngwarira kutsanya, sezvazvinogona kushatisa iyo polymer uye kukanganisa mhinduro dzemo.
Nguva yekundyepedzera: kupazwa kwakazara kweHPMC kunogona kutora maawa akati wandei, zvichienderana negiredhi regiredhi, saizi yechikuru, uye kushungurudzika. Ramba uchimutsa kusvikira mhinduro yanyatsojeka, inoonekera, uye yakasununguka kubva kuzvimisikidzwa zvinooneka kana aglomerates.
ph kugadzirisa (kana zvichidikanwa): mune zvimwe zvekugadzira, ph kugadzirisa kungave kuri madikanwa kuti uwedzere kugadzikana uye kuita kweHPMC solution. Shandisa zvakakodzera buffering vamiririri kana gadzirisa iyo pH uchishandisa acids kana zvigadziko seyakananga zvinodiwa.
Filtration (kana zvichidikanwa): Mushure mekupedzwa kwakazara, fara iyo hpmc solution kuburikidza neiyo yakanaka mesh sieve kana pepa rekubvisa chero zvimedu zvisingaonekwe kana kusvibiswa. Iyi nhanho inovimbisa kujekesa uye homogeneity yemhinduro.
Kuchengetedza uye kugadzikana: Chengetedza iyo Yakagadzirirwa HPMC Solution mune yakachena, midziyo yemoto kure kubva kune yakananga zuva uye kupisa kwakanyanya. Mhinduro dzakachengetedzwa zvakanaka dzinoramba dzakatsiga kwenguva yakareba pasina shanduko yakakosha muViscosity kana zvimwe zvivakwa.
Zvinhu zvinokanganisa kuvhiringidzika kweHPMC:
Zvinhu zvinoverengeka zvinogona kupesvedzera maitiro ekunyungudika uye zvivakwa zveHPMC Solution:
Chikamu cheKutarwa uye Giredhi: Akapamhama Giredhi eHPMC Dissolve zvakanyanya nyore pane coarse zvidimbu nekuda kwekuwedzera nzvimbo uye nekukurumidza hydration kinetics.
Kupisa
Kurumidza kumhanya: kusawirirana chaiko kunovimbisa yunifomu yekupararira kweHPMC zvikamu uye zvinosimudzira kuparara nekukurumidza. Kuwanika kwakanyanya kunogona kuunza mhepo mabhuru kana foam mune mhinduro.
Unhu hwemvura: Unhu hwemvura hunoshandiswa pakupera zvinokanganisa kujekesa, kugadzikana, uye viscosity yeHPMC solution. Yakacheneswa kana yakacheneswa mvura inosarudzwa kuderedza kusachena uye ion inogona kukanganisa nekupararira.
PH: iyo pH yemhinduro inogona kupesvedzera iyo solubility uye kugadzikana kweHPMC. Kugadzirisa iyo pH mukati meiyo yakasarudzika huwandu hwegiredhi reHPMC inogona kuwedzera kupaza uye kuita.
Ionic Simba: Yakanyanya kutarisisa yemaronda kana ions mune mhinduro inogona kukanganisa neHPMC kuputswa kana kukonzera gelation. Shandisa madhiri akaomeswa kana gadzirisa musangano wemunyu sezvazvinodiwa.
Shear Solces: Yakakwirira-Shear Kusanganisa kana mamiriro ekugadzirisa kunogona kukanganisa zvimiro zvakatsanangurwa uye kuita kweiyo hpmc solution, kunyanya mumaindasitiri ekushandisa.
Kutambudza Matipi:
Kana ukasangana nematambudziko mukunyungudika HPMC kana kusangana nenyaya nemhando yemhinduro, funga zvinotevera zvinotevera matipi ekugadzirisa dambudziko:
Wedzera kugezana: kusimudzira kusanganisa kusanganisa kana kushandisa nyanzvi yekubatanidza kusanganisa kusimudzira kupararira zviri nani kupararira uye kupaza kweHPMC zvikamu zveHPMC.
Gadzirisa tembiricha
Chikamu chekureka: shandisa mamakisi eHPMC kana kushandira saizi yekudzora maitiro akadai sekunyora kana micronization kuti uvandudze kupaza kinetics.
PH kugadzirisa: Tarisa iyo pH yemhinduro uye gadziridza sezvakakosha kuti urambe wakakwana mamiriro eHPMC salubility uye kugadzikana.
Mhando yemvura: Ita shuwa kuchena uye mhando yemvura inoshandiswa kupazwa nekushandisa yakakodzera filtration kana nzira yekuchenesa.
Kuedza kuenzanisa: Ita zvidzidzo zvinowirirana nedzimwe nzira dzekuumbwa kuti dzione chero kuwirirana kana kusakwanisa kunokanganisa kupaza.
Bvunza mirayiridzo yeMugadziri: Nhungamiro yemugadziri uye nhungamiro dzemakiromita eHPMC maererano nekunyungudika kwemamiriro ezvinhu, uye kusvinudzwa, uye kugadzirisa dambudziko.
Kunyungudutswa hydroxypropyl methylcellose (HPMC) mumvura idanho rakakosha mune dzakasiyana siyana maindasitiri maitiro, kusanganisira mishonga yemishonga, chikafu, kuvaka, uye cosmetics. Nekutevera maitiro anokurudzirwa uye achikurudzira zvinhu zvakakosha sehukuru hwenzvimbo, tembiricha, uye mhando yemvura, iwe unogona kuwana yunifomu uye yakagadzikana HPMC solution ine zvivakwa zvaunoda. Pamusoro pezvo, maitiro ekutambudza uye anogadzirisa maratidziro anogona kubatsira kukunda matambudziko uye kuve nechokwadi chekubudirira kweHPMC yemashandisirwo akasiyana siyana. Kunzwisisa maitiro ekunyungudika uye ayo
Kutumira Nguva: Mar-09-2024