Hydroxyprishpropyl methyl cellelose seye mishonga yekuenzanisa

Hydroxypruppyl methyl cellulose (HPMC)ishandare yemishonga yemishonga inoshandiswa zvakanyanya kushandiswa mumhando dzakasiyana-siyana dzemahara nekuda kwezvivakwa zvaro zvakasarudzika. Iyi cellulose inobviswa kubva ku cellulose, chiitiko chaicho chinoitika chinowanikwa muzvirimwa, uye chakagadziridzwa kuburikidza nemakemikari maitiro ekuwana hunhu hwaunoda. Muchirongwa chemishonga, HPMC inoshanda mabasa mazhinji, kusanganisira binder, firimu raimbova, thickener, stabilizer, uye akasimbisa-mumiriri. Chishandiso chayo chakapararira uye kukosha muindasitiri yemishonga yekunzwisisa kwakazara kwezvinhu zvayo, zvinoshandiswa, uye zvakanaka.

HPMC's Solubility uye viscosity zvivakwa zvinoita kuti ive sarudzo yakanaka yekudzora zvinodhaka mudhara mumuromo momuromo matope mafomu. Iyo inoumba gel matrix pamusoro pe hydration, iyo inogona kudzoreredza zvinodhaka nekusiyana kuburikidza neyakazvimba neyekuzvimba gel layer. Iyo viscosity yeiyo gel inoenderana nezvinhu zvakaita sehuremu hwemanyorerwe, degree rekutsiva, uye kusunganidzwa kweHPMC mukuumbwa. Nekuchinja aya paramita, masayendisiti emishonga anogona kudzora zvinodhaka zvekushandisa zvinodikanwa zvekurapa

HPMC inowanzo shandiswa seyekuchinjika muzvimiro piritsi kuti upe kubatana uye kugadzirisa simba rekusimbisa mahwendefa. Sekusvirwa, inosimudzira kudengenyeka kwechikamu uye kuumbwa kwehwendefa panguva yehomwe yekumanikidza maitiro, zvichikonzera mahwendefa neyunifomu yezvinyorwa zvinodhaka uye zvisingadzivisike. Pamusoro pezvo, HpMC's Film Filming Zvivakwa zvinoita kuti zviite kuti zviite kuti zviite mahwendefa ekuvhara, ayo anoshanda zvakaringana zvinangwa zvakaravira, kudzivirirwa kunonyungudza, uye kusimbiswa kwezvinodhaka.

Pamusoro pemuromo solid dosage mafomu, HPMC inowana mashandiro mune mamwe maficha emishonga, kusanganisira mhinduro dzePisharices, Gelical Gels, transdermal patches, uye inodzorwa-jekiseni. MuOphthalm Solutions, HPMC zviito seVisagsity-inosimudzira mumiririri, kuvandudza nguva yekugara yekuumbwa pane ocular pamusoro uye kusimudzira zvinodhaka. Mumatura epamusoro, inopa kudzora kwe rheological, kubvumira chikumbiro chiri nyore uye chakavandudzwa kuputika kweganda zvevhu zvinoshanda.

Hpc-Kubva patraness transdermal patches inopa iyo yakanakira uye isiri-Invasive Dishm yekutumira system yehurongwa hwehurongwa hwehurongwa hwehurongwa hwekusarudzika Iyo polymer matrix inodzora budiriro yezvinodhaka kuburikidza neganda pamusoro penguva yakareba, kuchengetedza maratidziro ekurapa mushonga mukupa kweropa apo kuderedza kuchinjika. Izvi zvinonyanya kubatsira kuti zvinodhaka neanotetepa mahwindo kana iya inoda kuenderera mberi kutonga.

HPMC's Biocomputer uye Inserness inoita kuti iite kuti ishandiswe mukuumbwa kwevabereki seyekumhanyisa mumiriri kana viscossity modifier. Mune inodzorwa-kuburitswa majekiseni, HPMC microspheres kana nanharticles inogona kusimudzira manyorerwo emubhadharo, inopa kuburitswa kwekuwedzera pamusoro penguva yakareba, nekudaro ichidzikisa kuwanda uye nekuvandudza kutevedzera kwemurwere.

HPMC inoratidza mucoadhesive zvivakwa, zvichiita kuti zvive zvinobatsira mukuumbwa kwakagadzirirwa mucosal zvinodhaka, senge buccal films uye nasal sprays. Nekunamatira kune mucosal maficha, HPMC inowedzera zvinodhaka nguva yekugara, ichibvumira kusimudzira zvinodhaka zvinodhaka uye kushayikwa.

HPMC inowanzo zivikanwa seyakachengeteka (Gras) nevematare ekudzora akadai seUS chikafu uye zvinodhaka zvekutonga Yayo biodegradability uye isiri-ine chepfu chimiro chinowedzera kukwezva kufadza kwayo seyechikamu chekisheni.

Hydroxypruppyl methyl cellulose (HPMC)ishandare yemishonga yemishonga ine mari yekusiyana-siyana mafambiro akasiyana siyana emhando dzakasiyana siyana. Zvivakwa zvaro zvakasarudzika, kusanganisira solubility, viscosity, firimu-kugadzira kugona, uye biocomputility, ita chinhu chakakosha, chivharo chakakosha mune zvinogadzirwa zvinokonzeresa zvinangwa zvekurapa. Sezvo mishonga yekutsvaga inoenderera mberi kusimuka, HPMC inogona kuramba iri dombo rakanaka mukuvandudzwa kwekushandiswa kwezvinhu zvinodhaka uye mafambiro.