Hydroxyprupyl methylcellose (HPMC)Inoshandiswa basa rakawanda rinoshandiswa zvakanyanya mune mishonga yemishonga, zvigadzirwa zvekudya, zvigadziriso, uye zvinoshandiswa maindasitiri. HPMC inokosheswa nekugona kwayo kuumba gels, mafirimu, uye nemvura yayo yekunakidzwa. Nekudaro, tembiricha yegungwa yeHPMC inogona kuve yakakosha chinhu mukushanda kwayo uye kuita mune dzakasiyana siyana. Tembiricha-ine hukama neyakafanana neyakawisira kupisa
Kunzwisisa HydroxyPropyl Methylcellose (HPMC)
HydroxyPropyl methylcellose ndeye cellulose inobva kune mamwe mapoka eiyo mapoka emherkhulose anotsiviwa nehydroxyprupropropyl uye methyl mapoka. Uku kugadziridzwa kunowedzera iyo polymer's solubility mumvura uye inopa kutonga kuri nani pamusoro pegwenzi neViscosity zvivakwa. Chimiro chePolymer chinopa iyo kugona kuumba gels kana mumvura mhinduro, ichiita kuti ive yakasarudzika muindasitiri akasiyana siyana.
HPMC ine chivakwa chakasarudzika: Iyo iri pasi pegwenzi pane chaiyo tembiricha kana ikanyungudika mumvura. Maitiro eHPMC anokurudzirwa nezvinhu zvakadai senge smedilar uremu, iyo degree rekutsiva
Geation tembiricha yeHPMC
GELASE Tembiricha inoreva tembiricha iyo HPMC iri pasi pekutendeuka kweshanduko kubva kune yemvura mamiriro kusvika kune gel State. Ichi chikamu chevhu chakakanganisika mune dzakasiyana-siyana mafambiro, kunyanya kune zvigadzirwa zvemishonga uye cosmetic zvigadzirwa zvinoenderana nekuenderana uye chimiro chinodiwa.
Iyo magasi maitiro eHPMC inowanzoonekwa neyekushomeka kwegwenzi (CGT). Kana mhinduro yacho ichinge yatsva, iyo polymer inotsemuka hydrophobic yekudyidzana inokonzera kuungana uye kuumba gel. Nekudaro, tembiricha iripo iyo inoitika inogona kusiyana zvichienderana nezvikamu zvinoverengeka:
Sreek inoremerwa: Yakakwira Molecular uremu HPMC mafomu jekeri munzvimbo dzakakwirira. Zvekare, kuderera molecular uremu HPMC kazhinji mafomu emazaya jekesi pakudziya tembiricha.
Degree rekutsiva (DS). Dhigirii rakakwirira rekutsiva
Kusvinura.
Kuvapo kweIons: Mumvura mhinduro, ion inogona kukanganisa maitiro ehuswa eHPMC. Kuvapo kwemazaru kana mamwe magetsi anogona kushandura kudyidzana kwePolymer nemvura, kufurira tembiricha yayo yegungwa. Semuenzaniso, kuwedzera kweSodium chloride kana potassium mapepa anogona kudzikisa tembiricha yekupisa nekudzora hydration yemaketani emapolymer.
pH: Iyo pH yemhinduro inogona zvakare kukanganisa maitiro egungwa. Sezvo HPMC isingarerekera mumamiriro mazhinji, shanduko pH inowanzove nemhedzisiro madiki, asi zvakanyanyisa ph mazinga zvinogona kukonzera kusvibiswa kana kushandura maitiro egwenzi.
Matambudziko ekudziya muHPMC GENLIST
Nhau dzinoverengeka dzine chekuita ne tembiricha dzinogona kuitika panguva yekuumbwa uye kugadzirisa kweHPMC-based magri eGels:
1. Yakatangira Green
Precure Yakatangira Inoitika Kana Polymer inotanga kugeza pane yakadzika tembiricha pane yaunoda, ichiita kuti zviome kugadzirisa kana kubatanidza mune chigadzirwa. Nyaya iyi inogona kumuka kana tembiricha yegungwa iri padyo zvakanyanya kune ambient tembiricha kana tembiricha.
Semuenzaniso, mukugadzirwa kwemishonga yechechi kana kirimu, kana iyo HPMC solution inotanga kusanganisa kana kuzadza, inogona kukonzera blockges, kusawirirana, kana kusasimba kusimbisa. Izvi zvinonyanya kunetsa mukugadzirwa kukuru-kwakakura, uko kwakanyatsoita tembiricha kutonga kuri madikanwa.
2. Isina kukwana green
Kune rimwe divi, isina kukwana gwenzi rinoitika kana iyo polymer haina gel sekutarisirwa pakudziya kwekudziya, zvichikonzera mumunun'una kana kuderera-viscosity chigadzirwa. Izvi zvinogona kuitika nekuda kwesarudzo isiriyo yePolymer solution (yakadai sekusina kusarudzika kana isina kukodzera molecular uremu hpmc) kana isina kukwana tembiricha yekudzora panguva yekugadzirisa. Isina kukwana green inowanzoonekwa kana iyo polymer yekushomeka yakaderera, kana mhinduro yacho haisvike iyo inodiwa yekupisa kweiyo tembiricha yenguva yakakwana.
3. Kusagadzikana kweTermal
Kusagadzikana kwekuparadza kunoreva kuputswa kana kusvibiswa kweHPMC pasi pemamiriro ekunze ekushisa. Nepo HPMC yakagadzikana, kuratidzwa kwenguva refu kusvika pakupisa kwakanyanya kunogona kukonzera hydrolysis ye polymer, ichidzora uremu hwayo uye, nekudaro, kugona kwayakaita. Uku kushatisa kunopisa kunotungamira kune isina kusimba gel chimiro uye shanduko mune zvivakwa zvemuviri zvegwenzi, senge soder viscosity.
4. Viscosity kutsvedza
Viscosity kutsvedza kweimwe dambudziko rinogona kuitika neHPMC Gels. Tembiricha kusiyana panguva yekugadzirisa kana kuchengetedza kunogona kukonzera kushandurwa muViscosity, inotungamira kune isingaenderane nechigadzirwa mhando. Semuenzaniso, paakachengetwa pakukwirira kwe tembiricha, gel inogona kuve yakaonda zvakanyanya kana kukora zvakaringana zvichienderana nemamiriro ekunze akaiswa pasi. Kuchengeta tembiricha inoenderana inokosha kuti ive nechokwadi chekutakura viscosity.
Tafura: Mhedzisiro yekushisa pane HPMC GLALLAST ZVIMWE
| Paramende | Mhedzisiro ye tembiricha |
| Kupisa kwegungwa | Kupisa kweGloce Kuwedzera neMelecular Urege HPMC uye kuderera neakakwira dhigirii rekutsiva. Iyo inosetsa yegungwa tembiricha (CGT) inotsanangura shanduko. |
| Viscosity | Viscosity inowedzera seHPMC iri pasi pegwenzi. Nekudaro, kupisa kwakanyanya kunogona kukonzera iyo polymer kune degrade uye yakaderera viscosity. |
| Sreek inoremerwa | Yakakwira Molecular uremu HPMC inoda kupisa kwakanyanya kuGel. Yakaderera molecular uremu hpmc gels pane yakaderera tembiricha. |
| Kusvinura | Yakakwirira polymer kutarisisa inoguma nekukasira kugomba kupisa, sezvo ngetani dzePolymer dzinofambidzana zvakanyanya. |
| Kuvapo kweIon (munyu) | Ions inogona kuderedza kupisa kwegungwa nekusimudzira polymer hydration uye kuvandudza hydrophobic kutaurirana. |
| pH | PH kazhinji ine madiki madiki, asi zvakanyanyisa PH kukosha kunogona kukanganisa iyo polymer uye kushandura maitiro egungwa. |
Mhinduro dzekugadzirisa tembiricha-dzine chekuita nematambudziko
Kuti uderedze matambudziko okushora-tembiricha muHPMC Gel mafomu, iyo nzira dzinotevera dzinogona kushandiswa:
Simbisai suremu uye degree rekutsiva. Yakadzika molecular uremu HPMC inogona kushandiswa kana iyo yakadzika geli tembiricha ichidikanwa.
Kudzora kusungwa: Kugadzirisa kusunganidzwa kweHPMC mumhinduro kunogona kubatsira kudzora tembiricha yegungwa. Nzvimbo dzakakwirira dzakanyanya kukurudzira kuumbwa kweGel kuderera kupisa.
Shandisa kwekushisa-kudzorwa kwekugadzirisa. Tembiricha yekudzora masisitimu, yakadai sekusanganisa masanganiswa matangi uye masisitimu ekutonhora, anogona kuve nechokwadi chekuenderana.
Batanidza stabilizers uye co-solventts.
Monitor ph uye ionic simba: Izvo zvakakosha kudzora iyo pH uye ionic simba remhinduro yekudzivirira kusingafadzi shanduko mukuita magasi maitiro. Iyo buffer system inogona kubatsira kuchengetedza mamiriro akakwana ekuumbwa kweGel.
Nyaya dzinoenderana neyakaenderana neHpcGeli dzakakosha kukero yekukatyamadza yechigadzirwa chechigadzirwa, kungave kwemishonga yemishonga, cosmetic, kana zvekudya zvekudya. Kunzwisisa zvinhu zvinopesvedzera tembiricha yemagasi, senge sorreur uremu, kusvinura, uye kuvapo kweVick Kudzora kwakakodzera kwekugadzirisa tembiricha uye mafomu ekuumbwa kunogona kubatsira kudzikisira matambudziko kufanana neGreen, isina kukwana Greenctuations, uye ichisimbisa kugadzikana uye kushanda kweHPMC-based zvigadzirwa.
Kutumira Nguva: Kukadzi-19-2025