Hydroxyprishpyl methylcellose model musiyano

Hydroxyprupyl methylcellose (HPMC)Icho chiitiko chose chinoshandiswa zvinoshandiswa mumaindasitiri akasiyana-siyana, kusanganisira mishonga yemishonga, chikafu, zino, uye kuvaka. Zvivakwa zvayo uye zvikumbiro zvinosiyana zvichienderana nemuchero wayo wemanyoreri, izvo zvinogona kugadziriswa kuti zvienderane nezvinodiwa chaizvo.

Chemical dhizaini:

HPMC ndeyekuti inobviswa cellulose, polymer yakasikwa inowanikwa mune zvidyarwa.
Iyo hydroxypruppropyl uye methyl istsinders yakabatanidzwa kune iyo hydroxyl mapoka eCellulose Backbone.
Iyo chiyero chevadzidzi ava chinosarudza zvinhu zveHPMC, senge solubility, gelation, uye kugona kwemafirimu.

Subgray degree (DS):

DS inoreva kune iyo avhareji nhamba yemapoka echigadziko pane glucose unit mune cellulose backbone.
Yakakwira DS inokoshesa zvinokonzerwa nekuwedzera hydrofiripi, solubility, uye magazini.
Low DS HPMC yakanyanya kugadzikana uye ine unyoro unyoro hwekunyengerera, ichiita kuti zviite kuti zviite zvekushandisa mune zvekuvaka zvinhu.

Solecular uremu (MW):

MaElecular uremu hunokanganisa viscosity, firimu rekugadzira kugona, uye michina manhamba.
Yakakwira Molecular uremu HPMC kazhinji ine yepamusoro viscosity uye zviri nani firimu-inoumba midziyo yekugadzira, ichiita kuti iite kuti ishandiswe mukugadziriswa kwemishonga yekuchengetedza.
Lower sortle uremu akasiyana siyana anofungidzirwa kuti zvikumbiro zvadzinoita viscosity uye nekukurumidza kupaza zvinodiwa, zvakadai sepamhepo uye kuomerera.

Saizi yechikuru:

Saizi saizi inokanganisa poda inoyerera zvivakwa, kupaza chiyero, uye kusafanana mune zvekuumbwa.
Saizi yakanaka yemakona HPMC inopararira zvakanyanya mumvura mhinduro, inotungamira kuyamwisa hydration uye kuumbwa kweGel.
Coarser zvimedu zvinogona kupa zviri nani kuyerera zvivakwa mumidziyo yakaoma asi ingangoda nguva refu nguva refu.

Kupisa kweGeation:

Kupisa kweGegul kunoreva tembiricha iyo iyo HPMC mhinduro pasi pekuchinja kubva mumhinduro yegwenzi.
Yakakwirira kutsiva mazinga uye masero emanyorerwo anowanzotungamira kudzikisa kupisa kwegwenzi.
Kunzwisisa tembiricha yakakanganisika mukuenzanisa kudzorwa-kubudiswa zvinodhaka kuburitsa uye mukugadzirwa kwegiri dzezvinyorwa zvekushandisa zvepamusoro.

Formal Properties:

Kugadzikana kweTermal kwakakosha mukushandisa uko HPMC kunoiswa pakupisa panguva yekugadzirisa kana kuchengetedza.
Yakakwira DS HPMC inogona kuratidzira pasi pasi kugadzikana kwekutonga nekuda kwekuvapo kwemamwe maLibile libile sosi.
Ongorora yekuongorora nzira dzakadai sekusiyanisa calorning calarimetry (DSC) uye thermogravimetric kuongorora (tga) inoshandiswa kuongorora zvinhu zvekupisa.

Solubility uye kuzvimba maitiro:

Solubility uye kuzvimba kwemaitiro kunoenderana neDS, mamorekuru, uye tembiricha.
Yakakwira DS uye molecular uremu akasiyana kazhinji inoratidzira yakakura solubility uye kuzvimba mumvura.
Kunzwisisa Solubility uye Kuzvimba Kwekutsoropodza mukugadzira kudzora-kusunungura zvinodhaka zvekutumira uye kuumba hydrogels kune biomedical appication.

Rheological Properties:

Rheological Properties yakadai seViscosity, Shear Matindu maitiro, uye viscoellasity yakakosha mune dzakasiyana siyana application.
HpcSolutions inoratidzira pseudoplastic maitiro, uko viscosity inoderera nekuwedzera shear rate.
Iyo rheological zvivakwa zveHPMC inokanganisa maitiro ayo mumaindasitiri akadai sechikafu, zvizoro, uye mishonga.

Misiyano iri pakati pezvikamu zvakasiyana zveHPMC stem kubva kusiyane muMakemikari Chimiro, SEXCELE SEATH, SICARTELE, SOLUBILLE, SOLUBLICE maitiro, uye maitiro ekuzvimba. Kunzwisisa misiyano iyi kwakakosha kusarudza iyo yakakodzera HPMC akasiyana ezvinyorwe zvikumbiro, kubva pamishonga yemishonga yekugadzira kune zvekuvaka zvinhu.