HpMc inokwira mhou mumvura inopisa here?

Hydroxyprupyl methylcellose (HPMC)Iyo polymer inoshandiswa kwazvo inowana shandisa zvakanyanya mumagisheni akasiyana-siyana senge mishonga, cosmetics, kuvaka, uye chikafu. Imwe yezvinhu zvayo zvisina kujairika ndeyekunyama kwayo mumvura, kunyanya mumvura inopisa.

1. Chii hpmc?

HPMC ndeye semi-synthetic, inert, viscoelastic polymer inotorwa kubva ku cellulose. Iyo inowanikwa nekurapa cellulose neAlkali uye profily oxide, ichiteverwa nesimbi. Iyi process inoguma mumvura-yakadzika polymer ine yakavandudzwa zvivakwa pamusoro pemasikirwo cellulose.

2. Solubility yeHPMC mumvura

HPMC inoratidzira yakanakisa solubility mumvura, kunyanya kana mvura yatsvairwa. Iyi solubility inokonzerwa nekuvapo kwemapoka ehydrophilic mukati meHPMC mamorekuru, kureva hydroxyl (-OOOH) mapoka uye ether. Aya mapoka anofambidzana nemamolekyudhi emvura kuburikidza neHydrogen kusungwa, kufambisa kupaza kweHPMC mumvura yemvura.

3. Mhedzisiro yekupisa pane solubility

Iyo solubility yeHpcinowedzera nekushisa. Kumba kwakakwirira, mamorekuru emvura ane simba rakakura kwazvo, rinotungamira kuti riwedzere kufambisa molecular uye kuputika kwemvura muPolymer Matrix. Izvi zvinoguma nekukurumidza kupaza kinetics uye yepamusoro solubility yeHPMC mumvura inopisa ichienzaniswa nemvura inotonhora.

4. Chikumbiro muFmaceutal Formasi

Muchirongwa chemishonga, HPMC inowanzoshandiswa semumiriri akakomberedzwa, stabilizer, uye yefirimu yaimbova mumuromo momuromo solid dosage mafomu akadai sehata nemapiritsi. Yayo solubility mumvura inopisa inoita kuti iite yakakodzera kugadzirira mhinduro dzemukati kana kumiswa kwezvinodhaka zvekugadzira zvinodhaka. Semuenzaniso, HPMC inogona kunyungudutswa mumvura inopisa kuti iite viscous gel, iyo inogona kuzoshandiswa seyekuchinjika kuti iwane zvinodhaka zvibodzwa mukugadzira piritsi.

5. Shandisa mune zvekuvaka

Muindasitiri yekuvaka, HPMC inoshandiswa muzvivakwa zveComent-based sile adhesives, motokari, uye dzorera. Yayo solubolity yemvura inobvumidza kuparadzaniswa nyore uye kugoverwa kwunifomu mukati meiyo coment matrix. Nekugadzira iyo firimu yekudzivirira kutenderera coment zvikamu, HPMC inovandudza kushanda, kuchengetwa kwemvura, uye kuderedza kwezvinhu izvi zvekuvaka.

6. Kukosha muindasitiri yechikafu

HPMC zvakare inotorawo basa rakakosha muindasitiri yechikafu, uko kwashandirwa seyekukasira, emulsifier, uye stabilizer mune dzakasiyana siyana zvekudya. Yayo solubility mumvura inopisa inogonesa kugadzirira kwemhinduro yakajeka, viscous iyo inobatsira kune inodiwa chimiro uye kusawirirana kwekudya kwekudya. Semuenzaniso, HPMC inogona kunyungudutswa mumvura inopisa kuti iite gel, iyo inozowedzerwa kune sosi, soups, kana messaps yekuvandudza muromo wavo nemuromo.

7. Mhedziso

Hpcinonyudza mumvura inopisa, nekuda kwayo hydrophic chimiro uye yakasarudzika makemikari chimiro. Ichi chivakwa chinoita kuti ive yakakosha musimboti mune dzakasiyana siyana dzekushandisa maindasitiri akasiyana, kusanganisira mishonga yemishonga, kuvaka, uye chikafu. Kunzwisisa maitiro ekushandura kweHPMC kwakakosha kune vagadziri uye vagadziri kuti vagadzirise kushandiswa kwaro mune zvakasiyana-siyana zvigadzirwa uye mafomu.