1. Basic sumo yeHPMC
HPMC (Hydroxypropyl Methylcellulose)is a synthetic polymer compound inotorwa kubva kune yakasikwa cellulose. Iyo inonyanya kugadzirwa nemakemikari shanduko ye cellulose uye inoshandiswa zvakanyanya mumishonga, chikafu, cosmetics uye kuvaka. Nekuti HPMC inonyungudika mumvura, haina chepfu, haina kuravira uye isingatsamwise, yave chinhu chakakosha muzvigadzirwa zvakawanda.
Muindasitiri yemishonga, HPMC inowanzo shandiswa kugadzirira kugadzirira-kuburitswa kwemishonga, macapsule shells, uye stabilizers emishonga. Inoshandiswawo zvakanyanya muchikafu seyakakora, emulsifier, humectant uye stabilizer, uye inotoshandiswa sechinhu chakaderera-calori mune zvimwe zvekudya zvakakosha. Pamusoro pezvo, HPMC inoshandiswawo seyakakora uye inonyorovesa chinhu muzvizoro.
2. Kwakabva uye kuumbwa kweHPMC
HPMC is a cellulose ether inowanikwa nekugadziriswa kwemakemikari echisikigo cellulose. Cellulose pachayo i polysaccharide yakatorwa kubva mumiti, iyo inoumba chikamu chakakosha chechirimwa masero madziro. Kana uchigadzira HPMC, mapoka akasiyana anoshanda (akadai sehydroxypropyl uye methyl) anounzwa kuti avandudze kunyungudika kwemvura uye kukora zvivakwa. Naizvozvo, kunobva HPMC ndeyakasikwa chirimwa zvigadzirwa, uye maitiro ayo ekugadzirisa anoita kuti iwedzere kunyungudika uye kuita zvakasiyana.
3. Kushandiswa kweHPMC uye kubata nemuviri wemunhu
Nzvimbo yezvokurapa:
Muindasitiri yemishonga, kushandiswa kweHPMC kunonyanya kuratidzwa mukugadzirira kuburitswa kwezvinodhaka. Sezvo HPMC inogona kugadzira gel layer uye kunyatso kudzora kuburitswa kwemushonga, inoshandiswa zvakanyanya mukugadzirwa kwemishonga inoburitswa uye inodzorwa-inoburitswa. Pamusoro pezvo, HPMC inoshandiswawo sekapule goko remishonga, kunyanya mumakapuleti ezvirimwa (vegetarian capsules), uko inogona kutsiva yechinyakare mhuka gelatin uye inopa sarudzo-inoshamwaridzana nemuriwo.
Kubva pakuona kwekuchengetedza, HPMC inoonekwa seyakachengeteka sechinhu chemushonga uye kazhinji ine yakanaka biocompatibility. Nekuda kwekuti haina muchetura uye isinganzwisisi kumuviri wemunhu, iyo FDA (US Food and Drug Administration) yakabvumidza HPMC sekuwedzera kwechikafu uye zvinodhaka, uye hapana njodzi dzehutano dzakakonzerwa nekushandiswa kwenguva refu dzakawanikwa.
Indasitiri yechikafu:
HPMC inoshandiswa zvakanyanya muindasitiri yezvekudya, kunyanya seyakakora, stabilizer, emulsifier, etc. Inoshandiswa zvakanyanya mukugadzirira-ku-kudya chikafu, zvinwiwa, zvihwitsi, zvigadzirwa zvemukaka, hutano chikafu uye zvimwe zvigadzirwa. HPMC inowanzo shandiswawo mukugadzirwa kwezvinhu zvakaderera-calori kana zvakaderera-mafuta nekuda kweiyo inonyungudika mumvura, iyo inovandudza kuravira uye magadzirirwo.
HPMC muchikafu inowanikwa nekugadziriswa kwemakemikari yechirimwa cellulose, uye kusungirirwa kwayo uye kushandiswa kunowanzo kudzorwa zvakanyanya pasi pezviyero zvekushandiswa kwezvikafu zvinowedzera. Zvinoenderana neazvino tsvagiridzo yesainzi uye chiyero chekuchengetedza chikafu chenyika dzakasiyana siyana, HPMC inoonekwa seyakachengeteka kumuviri wemunhu uye haina kukanganisa kwakashata kana njodzi dzehutano.
Cosmetics industry:
Muzvizoro, HPMC inowanzoshandiswa seyakakora, emulsifier uye inonyorovesa chinhu. Inoshandiswa zvakanyanya muzvigadzirwa zvakadai semakirimu, zviso zvekuchenesa, maziso emeso, lipsticks, nezvimwewo kugadzirisa maitiro uye kugadzikana kwechigadzirwa. Nekuti HPMC ine hunyoro uye haina kutsamwisa ganda, inoonekwa sechinhu chinokodzera marudzi ese eganda, kunyanya ganda rinonzwa.
HPMC inoshandiswawo muzvizoro uye zvigadzirwa zvekugadzirisa ganda kubatsira kusimudzira kugadzikana uye kupinda kwezvinhu zvezvinodhaka.
4. Kuchengetedzwa kweHPMC kumuviri wemunhu
Toxicological evaluation:
Zvinoenderana netsvagiridzo yazvino, HPMC inoonekwa seyakachengeteka kumuviri wemunhu. Sangano reWorld Health Organisation (WHO), Food and Agriculture Organisation (FAO), neUS FDA vese vakaita ongororo dzakasimba pakushandiswa kweHPMC uye vanotenda kuti kushandiswa kwayo mumishonga uye chikafu pahuwandu hakuzokanganisa hutano hwevanhu. Iyo FDA inonyora HPMC se "inowanzo zivikanwa seyakachengeteka" (GRAS) chinhu uye inobvumira kuti ishandiswe sechikafu chinowedzera uye chinotora zvinodhaka.
Clinical research uye kuongorora nyaya:
Zvidzidzo zvakawanda zvekiriniki zvakaratidza izvozvoHPMChaikonzeri kukanganisa kwakashata kana mhedzisiro mukati meiyo yakajairika huwandu hwekushandisa. Semuenzaniso, kana HPMC ichishandiswa mukugadzirira kwemishonga, varwere kazhinji havaratidzi kusawirirana kana kumwe kusagadzikana. Mukuwedzera, hapana matambudziko ehutano anokonzerwa nekushandisa zvakanyanya HPMC muzvokudya. HPMC inoonekwawo yakachengeteka mune mamwe matunhu akasarudzika kunze kwekunge paine munhu allergic reaction kune ayo zvinosanganiswa.
Allergic reactions uye yakashata maitiro:
Kunyangwe HPMC isingawanzo kukonzeresa kusawirirana, nhamba diki yevanhu vane hanya zvakanyanya vanogona kusawirirana nazvo. Zviratidzo zveallergic reaction zvinogona kusanganisira kutsvuka kweganda, kukwenya, uye kutadza kufema, asi zviitiko zvakadaro hazviwanzo. Kana kushandiswa kwemishonga yeHPMC kuchikonzera kusagadzikana, rega kuishandisa nekukurumidza uye bvunza chiremba.
Migumisiro yekushandiswa kwenguva refu:
Kushandiswa kwenguva refu kweHPMC hakuzokonzerese zvinozivikanwa zvakaipa zvinokonzeresa pamuviri wemunhu. Zvinoenderana netsvagiridzo yazvino, hapana humbowo hwekuti HPMC ichakonzera kukuvadzwa kwenhengo dzakaita sechiropa neitsvo, uye hazvizokanganisa immune system yemunhu kana kukonzera zvirwere zvisingaperi. Naizvozvo, kushandiswa kwenguva refu kweHPMC kwakachengeteka pasi pechikafu chiripo uye zviyero zvemishonga.
5. Mhedziso
Semushonga unotorwa kubva kune zvakasikwa chirimwa cellulose, HPMC inoshandiswa zvakanyanya muminda yakawanda senge mushonga, chikafu uye zvizorwa. Huwandu hukuru hwezvidzidzo zvesainzi uye toxicological ongororo dzakaratidza kuti HPMC yakachengeteka mukati mehumwe hunyoro hwekushandisa uye haina inozivikanwa chepfu kana pathogenic njodzi kumuviri wemunhu. Kungave mukugadzirira kwemishonga, zvekuwedzera zvekudya kana zvekuzora, HPMC inoonekwa seyakachengetedzeka uye inoshanda musanganiswa. Ehe, pakushandiswa kwechero chigadzirwa, iyo yakakodzera mirairo yekushandiswa inofanirwa kuteverwa, kushandiswa kwakanyanya kunofanirwa kudzivirirwa, uye kunyatsotarisisa kunofanirwa kubhadharwa kune zvinogoneka munhu allergic reaction panguva yekushandiswa. Kana uine matambudziko akakosha ehutano kana zvinokunetsa, zvinokurudzirwa kuonana nachiremba kana nyanzvi.
Nguva yekutumira: Zvita-11-2024