Hydroxyprupyl methylcellose (HPMC)Inosulile polymer inowanzo shandiswa mune dzakasiyana siyana dzekushandisa, kusanganisira mishonga yemishonga, zvigadzirwa zvekudya, zvigadziriso, uye zvinoshandiswa nemaindasitiri. Unhu hweHPMC hunogona kusiyana zvichienderana nezvinhu zvakaita sehuremu hwemanyorero, viscosity, degree rekutsiva (DS), iro rakacheneswa zvakananga mukushandisa kwakananga.
Zvinhu zvakakosha zvinokanganisa kunaka kweiyo hydroxypropyl methylcellose
Sreek inoremerwa
Molecular uremu (MW) zvinoreva saizi yekusagadzikana®hpmc molecule uye inoita basa rakakosha mukutsanangura zvaro zvaro uye solubility. Yakakwira Molecular uremu HPMC inowanzove nekwakakwirira viscosity, iyo inobatsira mukushandiswa senge kusunungurwa kwezvinodhaka kana seyakagadzirirwa mumiririri akasiyana siyana.
Yakaderera molecular uremu (lmw).
Yakakwira Molecular uremu (HMW).
Degree rekutsiva (DS)
Dhigirii rekutsiva rinoreva kuti nderipi mapoka eHydroxyl pane iyo cellulose backbone inotsiviwa ne methyl uye hydroxyprupropyl mapoka. Chinhu ichi chinokanganisa iyo solubility uye rheological zvivakwa zve polymer.
Low DS: Yakaderedzwa mvura solubility, yakakwirira gel simba.
Yakakwira DS.
Viscosity
Viscosity chinhu chakakosha pane kuona kuti Hpmc yakadii kuita mukuita, kusimbisa, uye kugadzira maficha. Yakakwira viscosity HPMC inoshandiswa mukushandiswa kunge emulsions, kumiswa, uye hydrogels, nepo madhiri ekudzora eViscosity akakodzera chikafu uye mishonga yemishonga.
Yakadzika viscosity: Kazhinji inoshandiswa mune chikafu, kutarisirwa kwega, uye mishonga yemishonga yekuumbwa kwemafirimu uye kusunga
Yakakwira viscosity.
Kuchena
Chikamu chekusvibiswa, chakadai sokusara kwemasimba, mashanga emamiriro ekunze, uye zvimwe zvinosvibisa, zvinogona kukanganisa zvakanyanya kuita kwekusagadzikana®HPMC. Makumi ekunyatsochenesa mamakisi anowanzodikanwa mune mishonga uye yekudya zvikumbiro.
Pharmaceutical Giredhi.
Giredhi reindasitiri.
Solubility
Iyo solubility yeHPMC mumvura inoenderana nezvose zviri zviviri zvinorema uye huwandu hwekutsiva. Kazhinji, HPMC inonyura mumvura inotonhora, ichiita sarudzo yakanaka kwazvo yezvinhu zvakasiyana siyana izvo zvinoda mafomu ezvinyorwa zvakavakirwa mvura.
Yakaderera solubility: Zvishoma zvinonyangadza, zvinoshandiswa kune kudzorwa-kuburitsa masisitimu.
Solubility yakakwira.
Kugadzikana kweTermal
Iyo yekudzikiswa kweHPMC chikamu chakakosha, kunyanya mumaindasitiri ayo anosanganisira kugadzirisa tembiricha yakanyanya. Yakakwirira yekudyara inogadzikana inogona kuve yakakosha pakushandisa kunge mabhegi ekutema uye mune indasitiri yechikafu.
Gel Simba
Gel Simba rinoreva kugona kweHPMC kuti riite gel pakasanganiswa nemvura. Simba rakakwirira Gel rinodiwa mukushandisa sekushandiswa-kwakadzorwa
Tafura yekufananidza: mhando yemhando ye hydroxyprupyl methylcellose
| Chinhu | Low mhando HPMC | Yakakwirira mhando HPMC | Kukanganisa pane kuita |
| Sreek inoremerwa | Kuderera molecular uremu (lmw) | Yakakwira Molecular uremu (HMW) | LMW inodonha nekukurumidza, HMW inopa yakakwira viscosity uye godhi gels. |
| Degree rekutsiva (DS) | Low DS (Shoma Substitution) | Yakakwira DS (zvimwe kutsiva) | Yakadzika DS inopa Elet iri nani Gel Simba, yakakwira DS inovandudza kunyudza. |
| Viscosity | Yakadzika viscosity, kukurumidza kupera | Yakakwira viscosity, kuremedza, gel-kugadzira | Yepasi vhiza yakakodzera kuparadzaniswa nyore, yakakwira viscosity yekusagadzikana uye kusunungurwa kusunungurwa. |
| Kuchena | Yakakwirira mazinga ekusvibiswa (inorganic salts, solvent) | Kuchena kwakanyanya, kusara kwemasere | Kuchena kwakanyanya kunovimbisa kuchengetedzeka uye kushanda, kunyanya mumishonga uye chikafu. |
| Solubility | Solbol Solubility mumvura inotonhora | Yakanaka solubility mumvura inotonhora | Yakakwira Solubility inobatsira kune majasi uye nekukurumidza-kusunungura maficha. |
| Kugadzikana kweTermal | Kuderedza kupaza mari | Yakakwirira inogadziriswa | Yakakwirira yekudzikama yekukurudzirwa inofarira munzvimbo dzakakwirira-tembiricha. |
| Gel Simba | Low Gel Simba | Yakanyanya Gel Simba | Yakakwira gel simba rinodiwa kuti udzorerwe nekuburitswa uye majee masisitimu. |
| Chitarisiko | Yellowish kana ye-isina-chena, isinganzwisisike chimiro | Chena kuenda-chena, manyorerwo | Yakakwira-mhando HPMC ichave neyunifomu chitarisiko, inoratidza kusawirirana mukugadzirwa. |
Kunyorera-kwakavakirwa maitiro ekufunga
Indasitiri yeMishonga. Kuburitswa kwekudzorwa kweiyo inoshanda mishonga-epilients (APSI) inoenderana zvakanyanya nezvinhu zveHPMC, uko kwakakomba molecular uremu uye huwandu hwekutsiva hunobvumidza kuti dzisunungure
Indasitiri yechikafu: Zvezvekudya zvekudya, kunyanya mukushandisa senge zvekudya zvekudya, zvichiratidziridza vamiriri, uye emlsifiers, HPMC yezasi viscosity uye zvine mwero solubility inowanzoda. Yakakwira-mhando chikafu-giredhi hpmc inosimbisa kuchengetedza kwevatengi uye inosangana nezviyero zvekushandisa.
Cosmetic uye yekutarisira pachako. Pano, viscosity uye solubility zvakakosha kuti ugadzire kugadzikana maficha kunge lotions, kirimu, uye zvigadzirwa zvebvudzi.
Industrial inoshandisa. Iko kutarisisa kwekugadzikana kwekunyora, kuchena, uye viscosity iri paromount mukuita kuti ive yakajeka chigadzirwa kuita mumamiriro ezvinhu ane hutsinye.
Mhando yeHydroxypruppropyl methylcelloseinogona kukurudzira zvakanyanya kuita kwayo pamatanda akasiyana maindasitiri. Nekunzwisisa zvinhu zvinobatsira kune hwayo hwemhando, seruremu hwenyore, degree rekutsiva, kuvenga, kuchena, solubility, iwe unogona kusarudza giredhi rekurudyi rechishandiso chimwe nechimwe chekushandisa. Kunyangwe perviceceuceus kushandiswa, kugadzirwa kwechikafu, kana kugadzirwa kwemaindasitiri, kunoita kuti kugadzirwa kwemaindasitiri kweiyo HPMC kunosarudzwa kuchawedzera kushanda uye kushanda kwechigadzirwa chekupedzisira.
Kutumira Nguva: Jan-27-2025