1. Chii chinonzi hydroxypropyl methylcellulose?
Hydroxypropyl methylcellulose (HPMC)isiri-chepfu uye isingakuvadzi isiri-ionic cellulose ether, inoshandiswa zvakanyanya mukuvaka, chikafu, mishonga, zvizorwa uye mamwe minda. Iyo ine mabasa ekukora, kuchengetedza mvura, kugadzira firimu, kusungirirana, kukwirisa uye kuturika, uye inogona kunyungudika mumvura kuita inoonekera kana translucent viscous mhinduro.
2. Kushandiswa kwakajairika uye kushandiswa kweHPMC
Munda wekuvaka
HPMC inowanzoshandiswa mukuvaka zvinhu zvakadai sedhaka resimende, putty poda, tile inonamira, nezvimwe.
Basa: Kuvandudza mashandiro ekuvaka, kunatsiridza kuchengetwa kwemvura, kuwedzera nguva yakavhurika, uye kunatsiridza kuita kwekubatana.
Nzira yekushandisa:
Wedzera zvakananga kune yakaoma-yakasanganiswa dhaka, iyo inokurudzirwa mari ndeye 0.1% ~ 0.5% yehuwandu hwesamende kana substrate;
Mushure mekukurudzira zvakakwana, wedzera mvura uye simbisa muslurry.
Indasitiri yezvokudya
HPMC inogona kushandiswa seyakakora, stabilizer uye emulsifier, uye inowanzowanikwa mune zvekudya zvakaita seaizikirimu, jelly, chingwa, nezvimwe.
Basa: Kuvandudza kuravira, kudzikamisa sisitimu, uye kudzivirira stratification.
Kushandisa:
Dissolve mumvura inotonhora, iyo inokurudzirwa dosage inogadziriswa pakati pe0.2% ne2% zvichienderana nerudzi rwechikafu;
Kupisa kana mechanical kubvongodza kunogona kukurumidza kupera.
Pharmaceutical industry
HPMC inowanzo shandiswa mukuputira piritsi remishonga, inosimudzira-kuburitswa piritsi matrix kana capsule shell:
Basa: kuumbwa kwefirimu, kunonoka kuburitswa kwezvinodhaka, uye kudzivirira kwekuita kwezvinodhaka.
Kushandisa:
Gadzirira mukugadzirisa nekugadzirisa kwe1% kusvika ku5%;
Pfaya zvakaenzana pamusoro pehwendefa kuti uite firimu rakatetepa.
Cosmetics
HPMCinoshandiswa seyakakora, emulsion stabilizer kana firimu-forming agent, inowanzoshandiswa mumasiki kumeso, lotions, nezvimwewo:
Basa: Kuvandudza magadzirirwo uye kuwedzera kunzwa kwechigadzirwa.
Kushandisa:
Wedzera kune cosmetic matrix muchiyero uye simbisa zvakaenzana;
Iyo dosage inowanzo 0.1% kusvika 1%, inogadziriswa zvinoenderana nezvinodiwa zvechigadzirwa.
3. HPMC kuparara nzira
Kunyungudika kweHPMC kunokanganisa zvakanyanya nekupisa kwemvura:
Zviri nyore kunyunguduka mumvura inotonhora uye inogona kugadzira yunifomu mhinduro;
Haina kunyungudika mumvura inopisa, asi inogona kuparadzirwa uye kugadzira colloid mushure mekutonhora.
Matanho ekugadzirisa chaiwo:
Mwaya HPMC zvishoma nezvishoma mumvura, dzivisa kudurura zvakananga kudzivirira caking;
Shandisai kusanganisa kusanganisa;
Rongedza kugadzirisa kugadzirisa sezvinodiwa.
4. Kungwarira pakushandisa HPMC
Dosage control: Mumamiriro akasiyana ekushandisa, iyo dosage inobata zvakananga kuita uye inoda kuongororwa zvinoenderana nezvinodiwa.
Mamiriro ekuchengetedza: Inofanirwa kuchengetwa munzvimbo inotonhorera, yakaoma, inofefetera kudzivirira unyoro uye tembiricha yakakwira.
Kudzivirirwa kwezvakatipoteredza: HPMC inoodza uye haisvibise nharaunda, asi ichiri kuda kushandiswa nenzira yakamisikidzwa kudzivirira tsvina.
Kuenderana bvunzo: Kana yawedzerwa kune yakaoma masisitimu (senge zvizorwa kana mishonga), kuenderana nezvimwe zvinongedzo zvinofanirwa kuongororwa.
5. Zvakanakira HPMC
Zvisiri-chepfu, zvakatipoteredza, kuchengetedzwa kwepamusoro;
Yakasiyana-siyana, inochinjika kune zvakasiyana-siyana zvekushandisa zvinodiwa;
Kugadzikana kwakanaka, kunogona kuchengetedza kushanda kwenguva yakareba.
6. Matambudziko akajairika uye mhinduro
Dambudziko reAgglomeration: Teerera kune yakapararira yekuwedzera panguva yekushandiswa uye fambisa zvizere panguva imwe chete.
Yakareba nguva yekunyungudika: Mvura inopisa pretreatment kana mechanic inobvongodza inogona kushandiswa kukurumidza kupera.
Performance degradation: Teerera kune nzvimbo yekuchengetedza kudzivirira hunyoro uye kupisa.
Nekushandisa HPMC nesainzi uye zvine musoro, maitiro ayo akawanda anogona kushandiswa zvizere kupa mhinduro dzemhando yepamusoro dzemaindasitiri akasiyana.
Nguva yekutumira: Zvita-10-2024