HPMC (Hydroxypropyl Methylcellulose) chinhu chinonyungudika nemvura polymer musanganiswa unoshandiswa zvakanyanya mumishonga, chikafu, kuvaka, zvizorwa uye mamwe maindasitiri. HPMC is a semi-synthetic cellulose derivative inowanikwa nekemikari shanduko yeyakasikwa cellulose, uye inowanzo shandiswa seyakakora, stabilizer, emulsifier uye adhesive.
Zvenyama zvimiro zveHPMC
Nzvimbo yekunyunguduka yeHPMC yakanyanya kuomarara nekuti nzvimbo yekunyunguduka haina kujeka senge yezvakajairwa crystalline zvinhu. Nzvimbo yayo yekunyungudika inokanganiswa nechimiro chemolecular, huremu hwemamorekuru uye dhigirii rekutsiva hydroxypropyl uye methyl mapoka, saka inogona kusiyana zvichienderana neiyo chaiyo HPMC chigadzirwa. Kazhinji, sepolymer inonyungudika mumvura, HPMC haina nzvimbo yekunyungudika yakajeka uye yakafanana, asi inopfava nekuora mukati mehumwe tembiricha.
Melting point range
Maitiro ekupisa eAnxinCel®HPMC akanyanya kuomarara, uye maitiro ayo ekuparara kwemafuta anowanzo dzidza ne thermogravimetric analysis (TGA). Kubva muzvinyorwa, zvinogona kuwanikwa kuti nzvimbo yekunyunguduka yeHPMC ingangoita pakati pe200.°C uye 300°C, asi iyi renji haimiriri iyo chaiyo yekunyungudika yezvose HPMC zvigadzirwa. Mhando dzakasiyana dzezvigadzirwa zveHPMC dzinogona kunge dziine mapoinzi ekunyungudika akasiyana uye kugadzikana kwekupisa nekuda kwezvinhu zvakaita sehuremu hwemamorekuru, dhigirii reethoxylation (dhigirii rekutsiva), dhigirii rehydroxypropylation (dhigirii rekutsiva).
Low molecular uremu HPMC: Kazhinji inonyunguduka kana kupfava patembiricha yakaderera, uye inogona kutanga kuita pyrolyze kana kunyungudika kusvika mazana maviri.°C.
High molecular huremu HPMC: HPMC mapolima ane huremu hwepamusoro soro angada tembiricha yakakwira kuti inyunguduke kana kupfava nekuda kwengetani dzawo refu, uye kazhinji dzinotanga kunyungudika nekunyunguduka pakati pe250.°C uye 300°C.
Zvinhu zvinokanganisa nzvimbo yekunyungudika yeHPMC
Molecular uremu: Iyo molecular huremu hweHPMC ine hukuru hukuru pakunyungudika kwayo. Kudzika kwema molecular huremu kazhinji kunoreva kuderera kunyunguduka tembiricha, nepo huremu hwemamorekuru hunogona kutungamira kune yakanyanya kunyungudika.
Degree of substitution: The degree of hydroxypropylation (kureva the substitution reshiyo yehydroxypropyl mumorekuru) uye dhigirii remethylation (kureva reshiyo yereshiyo yemethyl mumorekuru) yeHPMC inokanganisawo painonyungudika. Kazhinji, dhigirii repamusoro rekutsiva rinowedzera kunyungudika kweHPMC uye inoderedza kunyungudika kwayo.
Hunyoro hwemukati: Sechinhu chinonyungudika nemvura, nzvimbo yekunyungudika yeHPMC inobatwawo nehunyoro hwayo. HPMC ine hunyoro hwepamusoro inogona kupinda hydration kana kupera zvishoma, zvichikonzera shanduko mukupisa kwekuora kwekushisa.
Thermal kugadzikana uye kuora kwekushisa kweHPMC
Kunyangwe HPMC isina kunyungudika kwakasimba, kugadzikana kwayo kwekupisa ndiyo kiyi yekuita chiratidzo. Zvinoenderana neiyo thermogravimetric analysis (TGA) data, HPMC inowanzotanga kuora mukati metembiricha ye250.°C kusvika ku300°C. The chaiyo decomposition tembiricha kunoenderana molecular uremu, dhigirii yokutsiva uye zvimwe muviri uye makemikari zvinhu HPMC.
Thermal kurapwa mune HPMC zvikumbiro
Mukushandisa, nzvimbo yekunyungudika uye kugadzikana kwekupisa kweHPMC kwakakosha. Semuyenzaniso, muindasitiri yemishonga, HPMC inowanzo shandiswa sechinhu chemakapisi, mabhaisikopo ebhaisikopo, uye vatakuri vemishonga inoburitswa. Mumashandisirwo aya, kugadzikana kwekupisa kweHPMC kunoda kusangana nezvinodiwa tembiricha yekugadzira, saka kunzwisisa maitiro ekupisa uye kunyungudika kwehuwandu hweHPMC kwakakosha kudzora maitiro ekugadzira.
Mumunda wekuvaka, AnxinCel®HPMC inowanzoshandiswa seyakakora mudhaka rakaoma, machira uye zvinonamira. Mumashandisirwo aya, kugadzikana kwekupisa kweHPMC kunofanirwawo kunge kuri mukati meimwe nhanho kuti ive nechokwadi chekuti haisi kuora panguva yekuvaka.
HPMC, sechinhu chepolymer, haina nzvimbo yakanyunguduka, asi inoratidza kupfava uye pyrolysis maitiro mukati mehumwe tembiricha. Nzvimbo yayo yekunyungudika inowanzova pakati pe200°C uye 300°C, uye iyo chaiyo yekunyungudika inoenderana nezvinhu zvakaita sehuremu hwemamorekuru, dhigirii rehydroxypropylation, dhigirii remethylation, uye hunyoro hwemukati hweHPMC. Mumamiriro akasiyana ekushandisa, kunzwisisa izvi zvimiro zvekupisa kwakakosha pakugadzirira uye kushandiswa kwayo.
Nguva yekutumira: Jan-04-2025