Hydroxyprupyl methylcellose (HPMC)Chimiro chakagadziridzwa chemakemikari chakagadziridzwa cellulose chinoshandiswa zvakanyanya mumhando dzakasiyana-siyana maindasitiri senge mishonga, kugadzirwa kwechikafu, uye kuvaka. Iyo inzvimbo yakati wandei, inowanzoshandiswa seyakakwenenzverwa, binder, firimu-fomu mumiririri, uye stabilizer. Nekudaro, haina kana yakatarwa "nhamba yerudzi" mutsika yechinyakare, sechigadzirwa kana chikamu chikamu chaungave iwe chaungawana mune mamwe maofaera. Panzvimbo iyoyo, HPMC inozivikanwa nemakemikari ayo emakemikari uye huwandu hwehunhu, hwakadai seyero yekutsiva neiscosity.
General ruzivo nezve hydroxyprusyl methylcellose (HPMC)
Chemical Stature: HPMC inogadzirwa nemakemikari kugadzirisa mheremalose kuburikidza nekutsiva kwehydroxyl (-OOH) mapoka ane hydroxypruppropyl uye methyl mapoka. Kutsiva kunoshandura zvivakwa zve cellulose, zvichiita kuti ive svutugadzike mumvura uye ichipa iyo yakasarudzika midziyo yakagadziridzwa firimu, inosunga kugona, uye kugona kuchengetedza zvinyoro.
Zvakajairika chiratidzo uye mazita
Kuzivikanwa kweHydroxyPropropyl methylcellose kazhinji kunoitika kune akasiyana-siyana emapepa ekutaurisa anotaurisa makemikari ayo emakemikari uye zvivakwa:
Nhamba nhamba:
Iyo yemakemikari inobvisa sevhisi (CAS) inopa chirevo chakasarudzika kune imwe neimwe yemakemikari chinhu. Nhamba yemasikati yeiyo hydroxyprupyl methylcellose ndeye 9004-65-3. Iyi inhamba yakaenzana inoshandiswa nevemakemikari, vatengesi, uye miviri yekudzora kutaura nezve chinhu.
Inchi uye anonyemwerera macode:
INCHI (International Cemical Sudentifier) ndiyo imwe nzira yekumiririra chimiro chemakemikari chechinhu. HPMC yaizove neyakagara Inchi tambo inomiririra iyo molecular chimiro muchimiro chakaumbwa.
Kunyemwerera HPMC zvakare ine iyo inoenderana inonamira kodhi, kunyangwe ichave yakanyanya kuoma nekuda kweiyo yakakura uye yakasarudzika chimiro chechimiro chayo.
Zvigadzirwa Zvinyorwa:
Mumusika wekushambadzira, HPMC inowanzoonekwa nenhamba dzechigadzirwa, dzinogona kusiyana nemugadziri. Semuenzaniso, mutengesi anogona kunge aine giredhi seHPMC K4m kana HPMC E15. Izvi zviziviso zvinowanzo tarisa kune vhiza yePolymer mune mhinduro, iyo inotarisirwa neiyo degree remagetsi uye hydroxypruproproproproproprolation pamwe nehuremu hwemanyorerwe.
Chaizvoizvo mamakisi e hydroxypropyl methylcellose (HPMC)
Hunhu hwe hydroxypropyl methylcellulose vary zvichienderana nedanho rekutsiva methyl uye hydroxpropropyl mapoka, pamwe nehuremu hwemanyorose. Iyi misiyano inotaura nezve HPMC viscosity uye solubility mumvura, izvo zvinokanganisa zvinoshandiswa maindasitiri akasiyana.
Pazasi patafura inobuda iyo akasiyana mamakisi e hydroxyprupyl methylcellose:
| Giredhi | Viscosity (cp mu 2% mhinduro) | Zvishandiso | Tsananguro |
| HPMC K4M | 4000 - 6000 CP | Pharmaceutical piritsi binder, indasitiri yechikafu, kuvaka (anomisheni) | Yepakati viscosity giredhi, inowanzoshandiswa mune yemuromo mafirita mafomu. |
| HPMC K100m | 100,000 - 150,000 CP | Inodzorwa-kuburitswa mafomu mune mishonga yemishonga, kuvaka, uye yekupenda machira | Yakakwira viscosity, yakanaka kwazvo yekuburitswa kwezvinodhaka. |
| HPMC E4M | 3000 - 4500 CP | Cosmetics, zvimbuzi, chikafu chekugadzirisa, zvinonamatira, uye kuungana | Nyura mumvura inotonhora, inoshandiswa mune zvigadzirwa zvega zvega uye zvinhu zvekudya. |
| HPMC E15 | 15,000 cp | Kukakavara mumiriri mune pendi, zvokurira, chikafu, uye mishonga | Yakakwira viscosity, nyura mumvura inotonhora, inoshandiswa muindasitiri uye zvigadzirwa zvechinangwa. |
| HPMC M4c | 4000 - 6000 CP | Chikafu uye chinwiwa chinwiwa senge stabilizer, pharmaceutical seyakagadzirwa | Mwero viscossity, kazhinji inoshandiswa seyekukakavara mune yakagadziriswa chikafu. |
| HPMC 2910 | 3000 - 6000 CP | Cosmetics (kirimu, lotions), chikafu (confectionery), mishonga (capsulules, macapings) | Imwe yemakirindi akanyanya, inoshandiswa sekusimbisa uye yakakora mumiririri. |
| HPMC 2208 | 5000 - 15000 CP | Yakashandiswa mumasimendi uye plaster mafomu, machira, mapepa ezvipenga | Kunaka kwekushandisa kunoda kunakidza mafirimu-ekuumba mafirimu. |
Yakatsanangurwa maumbirwo uye zvivakwa zveHPMC
Zvivakwa zvepanyama zve hydroxypruppropyl methylcellose zvinoenderana nehukuru hwenyika yekutsiva mapoka eiyo hydroxyl muCellulose Molecule. Heano midziyo mikuru:
Degree rekutsiva (DS):
Izvi zvinoreva kuti vangani vemapoka madiki emichero mu cellulose vakatsiviwa ne methyl kana hydroxpropropyl mapoka. Iyo degree rekutsiva rinokanganisa iyo solubility yeHpmc mumvura, zvavakaita, uye kugona kwayo kuumba mafirimu. Iyo yakajairika DS yeHPMC marara kubva 1.4 kusvika 2.2, zvichienderana negiredhi.
Viscosity:
HPMC mamakisi akakamurwa zvichienderana nekwavo zvavakatarwa kana zvichinyungudika mumvura. Iyo yepamusoro iyo smecular uremu uye iyo degree rekutsiva, yakakwira viscosity. Semuenzaniso, HPMC K100m (ine yakakwira viscosity renji) inowanzoshandiswa mune inodzorwa-kusunungura zvinodhaka mishonga yakaita seHPMC K4m inowanzo shandiswa kune piritsi mabheti uye zvekushandisa zvekudya.
Solubility yemvura:
Hpmc inochenesa mumvura uye inoumba chinhu chakaita sechigadzirwa kana ikanyungudika, asi tembiricha nePH inogona kukanganisa iyo solubility. Semuenzaniso, mumvura inotonhora, inopaza nekukurumidza, asi iyo solubility inogona kuderedzwa mumvura inopisa, kunyanya pakumanikidzwa kwakanyanya.
Firimu-kuumba kugona:
Chimwe chezvinhu zvakakosha zve hydroxypropyl methylcellose ndiko kugona kwayo kuumba firimu rinochinja. Ichi chivakwa chinoita kuti zviite kuti zvive zvakakodzera kushandiswa muzviyo zvebiritsi, kwainopa nzvimbo yakatsiga, yakadzorwa-kuburitswa. Izvo zvakare zvinoshanda muindasitiri yechikafu kuti uvandudze huwandu uye hupenyu hwesherufu.
GLALLE:
Pane zvimwe kutarisisa uye kupisa, HPMC kunogona kuumba gels. Ichi chivakwa chinobatsira mukuenzanisa kwemishonga, uko kwashandiswa kugadzira masisitimu ekudzora.
Zvikumbiro zve hydroxyprupyl methylcellose
Indasitiri yeMishonga:
HPMC inoshandiswa seyakagadzirwa mune tafura mafomu, kunyanya mukuwedzera-kusunungura uye kudzora-kusunungura masisitimu. Inoshandawo seyemumiriri wehonyeta wematafura uye makapu kudzora kusunungurwa kweiyo inoshanda chinongedzo. Kugona kwayo kuumba mafirimu akagadzikana uye gels akakodzera kune zvinodhaka kutumira masisitimu.
Indasitiri yechikafu
Muindasitiri yekudya, HPMC inoshandiswa seyemumiririri wakakura, emulsifier, uye stabilizer mune dzakasiyana siyana zvigadzirwa, kusanganisira masaga, zvipfeko, uye zvinhu zvakabikwa. Iyo inobatsira kuvandudza kuwanda uye kuwedzera hupenyu hwesherufu nekudzora kurasikirwa kunyoro.
Cosmetics uye hanya yemunhu:
HPMC inoshandiswa zvakanyanya mune cosmetics, kwainoita senge sedhese uye stabilizer mune krimu, lotions, shampoos, uye zvimwe zvigadzirwa zvemunhu pachako. Kugona kwayo kuumba chimiro cheGel chinonyanya kubatsira mune aya maapplication.
Indasitiri yekuvaka:
Mune indasitiri yekuvaka, kunyanya mumasimendi uye plaster mafomu, HPMC inoshandiswa seyemvura-inochengetedza mumiririri. Iyo inobatsira kuvandudza kushanda uye kunowedzera iyo yekubatanidza zvivakwa zvezvinhu.
Zvimwe Zvikumbiro:
HPMC inoshandiswawo muindasitiri yemiindanidzi, mapepa emapepa, uye kunyange mukugadzirwa kwemafirimu ebiadeable.
Hydroxyprupyl methylcellose (HPMC)Icho chiitiko chakanyanya-siyana chinoshandiswa mumigwagwa yakawanda nekuda kwezvinhu zvaro zvakasarudzika zvakadai sekugona kwemufirimu, kugona kukuru, uye kuchengetwa kwemvura. Kunyange zvisizvo Rudzi rwakasiyana-siyana rweHPMC runoratidzira kushanda kwayo muminda dzakasiyana, kubva pamishonga yemishonga yekudya, cosmetics, uye kuvaka.
Kutumira Nguva: Mar-21-2025