Hydroxyprupyl methylcellose (HPMC)Iyo inowanzoshandiswa cellulose inobviswa nehuremu hwakawanda hwekushandisa, kunyanya muminda yemishonga yemishonga, cosmetics, chikafu, uye zvekuvakisa. Haisi solvent, asi polymer ine mvura inogona kunyungudika mumvura uye gadzira mhinduro yakajeka coolidal. Iyo solubility yekusagadzikana ®hpmc zvinoenderana nenhamba uye chinzvimbo che methyl uye hydroxypruppropyl subsituents mune yayo molecular chimiro.
1. Zvekutanga zvivakwa zve hydroxypropyl methylcellose
Hydroxyprusyl methylcellose inowanikwa ne methylation uye hydroxypruslation ye cellulose. Cellulose pachayo ndeyechisikigo yepamusoro-molecular polysaccharide iyo iripo mumadziro echitokisi. Chemical chimiro cheHPMC chinonyanya kuumbwa neyechikamu cheGlucose, ayo ari manyorerwo emamolecules akabatanidzwa ne β-1,4 bonde zvisungo. Mune izvi molecular chimiro, mamwe mapoka eHydroxyl anotsiviwa ne methyl (-Och₃) uye hydroxypruppropyl (-c₃h₇opropyl (-c₃h₇oh (-c₃h₇oh), ichipa zvakanaka kugadzirisa uye kwemakemikari zvemuviri uye makemikari zvivakwa.
Iyo solubility yeHPMC inokanganiswa neiyo molecular chimiro uye kazhinji ine hunhu hunotevera:
Solubl Solubility: HPMC inogona kuumba mhinduro yeViscous mumvura uye ichipaza nekukurumidza. Yayo solubility ine hukama ne tembiricha yemvura uye inoremerwa uremu hwe hpmc.
Yakakwira viscosity: Pane imwe pfungwa, mhinduro yeHPMC inoratidza yakakwira viscosity, kunyanya pamakumbo akakwira mamexocular uremu uye huwandu hwepamusoro.
Kuumbwa kwaHupm kwa: HPMC ine yakagadzikana yakanaka pane imwe huwandu hwe tembiricha uye hazvisi nyore kupedza, saka zvine zvimwe zvakanakira maitiro ekugadzirisa.
2. Solubility yeHPMC
HPMC inzvimbo ine mvura inonyungudika, asi haina kunyungudutswa nemidziyo yese. Maitiro ayo ekunyungudika ane hukama nehuremu hweiyo solvent uye kuwirirana pakati peiyo solvent mamorekuru uye iyo HPMC mamorekuru.
Mvura: HpMC inogona kunyungudutswa mumvura. Mvura inonyanya kujairika solvent, uye panguva yekunyungudika, kusagadzikana®hpmc mamorekuru kuchaita hydrogen zvisungo nemamolekyudhi emvura kuti uwane kupaza. Dhigirii rekunyungudika rinokanganiswa nezvinhu zvakaita sehuremu hwe hpmc, degree remethylation uye hydroxyprustilation, tembiricha, uye ph kukosha kwemvura. Kazhinji, iyo solubility yeHPMC ndiyo yakanyanya kunaka mune isina kwayakarerekera.
Organic sol solventes: Hpmc yave kuita zvisingaonekwi mune yakawanda organic sol sol, yakadai seiyi alophols, ana nhanhatu, uye hydrocarbons. Izvi imhaka yekuti chimiro chayo chinoremerwa chine hydrophilic hydroxyl mapoka uye lipophic methyl uye hydroxpropropyl mapoka. Kunyangwe iyo ine hukama hwakasimba hwemvura, zvine hushoma hwakaenderana neyenzvimbo yakawanda sol.
Mvura inopisa yemvura: Mumvura inodziya (kazhinji 40 ° C kusvika 70 ° C), HPMC ichipaza nekukurumidza uye mhinduro yakadzikira inoratidza yakakwira viscosity. Sezvo tembiricha zvakare inowedzera, iyo yekunyorova uye solubility ichawedzera, asi pakupisa kwakanyanya, iyo tembiricha yemhinduro yemhinduro inogona kukanganiswa.
3. Kushandiswa kweHPMC
Nekuda kwekunyora kwayo kwemvura solubility, kuderera kwechisimba, uye kugadziridzwa viscosity, HPMC inoshandiswa zvakanyanya mumaindasitiri akasiyana siyana.
Indasitiri yePharmaceal: Muindasitiri yeMishonga, HPMC inoshandiswa zvakanyanya pakugadzirira-kusunungurwa-inogadzirira zvinodhaka, piritsi kuumbwa, matanda, uye vatakuri vezvinodhaka. Zvinogona kubatsira zvinodhaka zvinonyungudika mumvura uye kutungamira muyero wekuburitswa kwezvinodhaka.
Indasitiri yechikafu: Hpmc, sechikafu chinowedzera, chinowanzoshandiswa kuitira emulsification, kurerutsa, uye moisturizization. Muzvinhu zvakabikwa, zvinogona kuvandudza mikana uye kugadzikana kweupfu. HPMC inowanzoshandiswawo mune ice cream, zvinwiwa uye zvakaderera-mafuta chikafu.
Indasitiri yekuvaka: Mune indasitiri yekuvaka, HPMC inowanzoshandiswa seyakavharira yekuvaka mongwe, iyo inogona kuvandudza mashandiro ekuvaka, kuchengetwa kwemvura uye kushamwaridzana kwemutya.
Cosmetics: Mune cosmetics, kusagadzikana ®hpmc inonyanya kushandiswa seanomiririra, kushandiswa mumiriri uye stabilizer, shampoos, uye shages jege.
HpcIcho chidimbu-chinonaka uye chakanyanya viscous cellulose chinobva inga gadzira mhinduro yakajeka courlidal mhinduro mumvura. Haisi solvent, asi yakakwira moleky compind inogona kunyungudika mumvura. Yayo solubility inonyanya kuratidzwa mune yakanaka solubility mumvura, asi zvisikwa mune yakawanda organic sol sol. Aya maitiro eHPMC anoita kuti ishandiswe zvakanyanya mumaindasitiri mazhinji, kusanganisira mishonga yemishonga, chikafu, kuvaka, uye cosmetics.
Kutumira Nguva: Kukadzi-17-2025