Kuti tienzanise CMC (carboxymethylcellulose) uye HPMC (hydroxypropylmethylcellulose), tinofanira kunzwisisa zvinhu zvavo, zvikumbiro, zvakanakira, zvisingabatsiri, uye zvinogona kushandiswa. Zvese zviri zviviri zvinobuda mu cellulose zvinoshandiswa zvakanyanya mumaindasitiri akasiyana, anosanganisira emishonga, chikafu, zvekuzora uye kuvaka. Imwe neimwe ine yakasarudzika midziyo inoita kuti ive yakakodzera kune zvakasiyana zvinangwa. Ngatiitei kuenzanisa kwakadzama kwakadzama kuti tione kuti ndeipi iri nani mumamiriro akasiyana.
1. Tsanangudzo uye chimiro:
CMC (carboxymethylcellulose): CMC is water-soluble cellulose derivative inogadzirwa nekuita kwe cellulose uye chloroacetic acid. Iine mapoka e-carboxymethyl (-CH2-COOH) akasungirirwa kune mamwe mapoka e-hydroxyl e-glucopyranose monomers anoumba musana we cellulose.
HPMC (hydroxypropyl methylcellulose): HPMC zvakare inonyungudika selulosi derivative inogadzirwa nekurapa cellulose nepropylene oxide uye methyl chloride. Iyo ine hydroxypropyl uye methoxy mapoka akabatanidzwa kune cellulose musana.
2. Solubility:
CMC: Yakanyanya kunyungudika mumvura, ichigadzira yakajeka, viscous mhinduro. Iyo inoratidza pseudoplastic kuyerera maitiro, izvo zvinoreva kuti viscosity yayo inoderera pasi pekunetseka kweshear.
HPMC: Zvakare inonyungudika mumvura, ichigadzira zvishoma viscous mhinduro pane CMC. Inoratidzawo pseudoplastic maitiro.
3.Rheological properties:
CMC: Inoratidza shear kuonda maitiro, zvinoreva kuti viscosity yayo inodzikira nekuwedzera shear rate. Ichi chivakwa chinoita kuti chikodzere maapplication panodiwa kukora asi mhinduro inoda kuyerera zviri nyore pasi peshear, senge pendi, detergents nemishonga.
HPMC: inoratidzira yakafanana rheological maitiro kuCMC, asi viscosity yayo inowanzo kwira pakudzika kwakadzika. Iine zviri nani zvekugadzira firimu, zvichiita kuti ive yakakodzera kune zvikumbiro zvakadai semajasi, zvinonamira uye zvinodzorwa-kuburitsa kuburitswa kwemishonga.
4. Kugadzikana:
CMC: Kazhinji yakagadzikana pamusoro pehupamhi hwepH uye tembiricha. Inogona kushivirira mwero mwero we electrolytes.
HPMC: Yakagadzikana kupfuura CMC pasi pemamiriro ane acidic, asi inogona kuita hydrolysis pasi pemamiriro ealkaline. Iyo inonzwawo kune divalent cations, iyo inogona kukonzera gelation kana kunaya.
5. Application:
CMC: yakashandiswa zvakanyanya seyakaita thickener, stabilizer uye mvura-inochengetedza mumiririri muzvokudya (zvakadai seaizikirimu, muto), mishonga (yakadai semapiritsi, kuturika) uye zvizorwa (zvakadai sekirimu, lotion) maindasitiri.
HPMC: Inowanzo shandiswa mukuvaka zvinhu (semuenzaniso, simende zvinonamira, plaster, dhaka), mishonga yemishonga (semuenzaniso, inodzorwa-inoburitsa mahwendefa, ophthalmic gadziriro), uye zvizoro (semuenzaniso, madonhwe emeso, zvigadzirwa zvekuchengetedza ganda).
6. Muchetura uye kuchengeteka:
CMC: Inowanzo zivikanwa seyakachengeteka (GRAS) nemasangano anodzora kana ichishandiswa mukati memiganho yakatarwa muchikafu nemishonga yekushandisa. Iyo ine biodegradable uye haina chepfu.
HPMC: Zvakare inoonekwa yakachengeteka kushandiswa mukati memiganho yakakurudzirwa. Iyo biocompatible uye inoshandiswa zvakanyanya mumunda wemishonga seanodzorwa kuburitsa mumiriri uye piritsi binder.
7. Mutengo uye Kuwanikwa:
CMC: Kazhinji inodhura zvakanyanya kupfuura HPMC. Inowanikwa nyore nyore kubva kune vakasiyana vatengesi pasi rese.
HPMC: Inodhura zvishoma nekuda kwemaitiro ayo ekugadzira uye dzimwe nguva kushomeka kwekupa kubva kune vamwe vatengesi.
8. Kukanganisa kwezvakatipoteredza:
CMC: Biodegradable, inotorwa kubva kune inogona kuvandudzwa zviwanikwa (selulosi). Inofungidzirwa kuti inoshamwaridzana nemhoteredzo.
HPMC: Zvakare biodegradable uye inotorwa kubva ku cellulose, saka zvakare ine hushamwari hwakatipoteredza.
Ose ari maviri CMC uye HPMC ane akasiyana zvivakwa zvinoita kuti zvive zvakakosha zvekuwedzera mumaindasitiri mazhinji. Sarudzo pakati pavo inoenderana nezvinodiwa zvekushandisa senge solubility, viscosity, kugadzikana uye kutariswa kwemutengo. Kazhinji, CMC inogona kufarirwa nekuda kwemutengo wayo wakaderera, yakafara pH kugadzikana, uye kukodzera kwechikafu uye zvekuzora maapplication. HPMC, kune rumwe rutivi, inogona kufarirwa kune yakakwira viscosity, zvirinani zvekugadzira firimu, uye mashandisirwo emishonga uye zvekuvaka. Pakupedzisira, kusarudzwa kunofanirwa kuve kwakavakirwa pakufunga kuzere kwezvinhu izvi uye kuenderana neyakagadzirirwa kushandiswa.
Nguva yekutumira: Feb-21-2024