Pharmaceutical Exccient
Hydroxyprusyl methylcellose (HPMC) ine chena kana Milky White Viscous Coolidal Solution, inova mhinduro kana yadzorerwa, uye inova gel kana ichipiswa. HPMC haina kujekesa mu ethanol, chloroform uye ether. Izvo zvinonyangadza mune yakasanganiswa solvent ye methanol uye methyl chloride. Izvo zvakare zvinonyangadza mune yakasanganiswa solvent yeacetone, methyl chloride and isopropanol uye mamwe mamwe organic sol. Mhinduro yayo yemvura inogona kushivirira munyu (mhinduro yayo collodal haina kuparadzwa nemunyu), uye iyo pH ye1% mhinduro mhinduro ndeye 6-8. Iyo molecular formula yeHPMC ndeye C8H15O8- (C10H18O6) -C815O, uye hama yembeu inosvika zviuru makumi masere nezvishanu.
HPMC ine yakanakisa mvura solubility mumvura inotonhora. Inogona kuve yakanyungudutswa mumhinduro inojekesa ichimhanya zvishoma mumvura inotonhora. Kusiyana neizvozvo, zvakanyatsonaka mumvura inopisa pamusoro 60 × uye inogona kungozvimba. Icho chisiri-ionic cellulose ether. Mhinduro yayo haina iyo Ionic muripo, haipindire pamwe nesimbi yemasimbi kana ionic organic makomputa, uye haatendi nezvimwe zvinhu zvakabikwa panguva yekugadzirira maitiro; Iyo ine yakasimba anti-allergic zvivakwa, uye nekuwedzera kweiyo degree rekutsiva mumanyorerwo emanyorerwo, ayo acho anorwisa kuuraya uye akagadzikana; Iyo zvakare interbolday inert. Semhando yemishonga yemishonga, haina metabolized kana kubatwa. Naizvozvo, hazvipe macalorie mumishonga nezvikafu. Iyo yakaderera calorie, munyu-wakasununguka, uye isiri-munyu-isina varwere vane chirwere cheshuga. Allergenic zvinodhaka uye zvekudya zvine zvakasarudzika zvekushandisa; Izvo zvakakanganiswa neAcids neAlkalis, asi kana iyo PH Kukosha Kupfuura 2 ~ 11 uye inokanganiswa nekudziya kwakanyanya kana kune nguva yekuchengetera, zvavakaita vanoderera; Yayo yemvura mhinduro inogona kupa mamiriro epasi, kuratidza mwero mwero kusawirirana uye kusangana nekunetsana; Iyo ine emulsifiti inoshanda muchikamu chechipiri-chikamu, inogona kushandiswa sedanho rinobudirira uye rakadzivirirwa. Yayo yemvura mhinduro ine yakanaka firimu-inoumba zvivakwa, iri piritsi uye piritsi yakanaka yekubatanidza zvinhu. Iyo firimu yekuvhara yakaumbwa naro ine zvakanakira rusina ruvara uye kuomarara. Kuwedzera glycerin kunogona zvakare kuvandudza kupurasitiki kwayo.
Kusagadzikana
· Kamwe zvinyoro-nyoro mumvura uye akaiswa kuburikidza solvent, HPMC inoita kuti firimu rinoonekera riine simba rakakwirira.
· · Erinhans inosunga simba.
· Hurdrophilic Matrix pamwe neHPMC hydrate kuti ugadzire gel layer, kudzora kusunungura kwezvinodhaka.
| Kurudzira giredhi: | Kumbira TDS |
| HPMC 60X5 | Dzvanya apa |
| HPMC 6Ax15 | Dzvanya apa |