Warshaddu waxay sameysay iibka-iibinta HPMC K100m, cether celt, oo la mid ah Waloecel 45000, haynta biyaha wanaagsan
Waxaan hadda haysannaa qalabka sare. Ganacsadeena waxaa loo dhoofiyay Mareykanka, Boqortooyada Midowday iyo wixii la mid ah, ku raaxeysiga caannimada weyn ee warshadda ay ka dhigto hot-iibka ah Oo annaguna waxaan kuu xirxiran karnaa adiga shakhsi ahaan markaad iibsanayso.
Waxaan hadda haysannaa qalabka sare. Bakhaarkayaga waxaa loo dhoofiyaa Mareykanka, UK, ee Boqortooyada Midowday iyo wixii la mid ah, ay ku raaxeystaan sumcad weyn oo ku saabsan macaamiishaChina HPMC Kist kiimiko iyo budada HPMC, Isku-darka wax soo saarka soosaarka waaxyaha ganacsiga shisheeyaha, waxaan dammaanad ka qaadayn karnaa gaarsiinta waxyaabaha saxda ah meesha saxda ah, kaas oo ay taageerayaan awooda soosaarka badan, tayada wax soo saarka ee awoodda leh, tayada isdaba joog ah, waxyaabaha la kala soocayo Xakamaynta isbeddelka warshadaha iyo sidoo kale qaan gaadhnimadayada ka hor iyo ka dib adeegyada iibka. Waxaan jeclaan lahayn inaan kula wadaagno fikradaheena oo aan soo dhaweyno faallooyinkaaga iyo su'aalahaaga.
Sharraxaadda Wax soo saarka
Hydroxypropyl bylule (hpmc)
Qaaciddada molika
Hab-daran (hydroxypropythythylcellosure: HPMC) Beddelka nooca 2910, 2906, 2208 (USP)
Guryaha jireed
- cad ama budada cad ee huruudda ah
- Ku milatarida isku dhafka ah ama aqueous
- Sameynta filim hufan oo hufan markii xalka ka saar
- Wax falcelin kiimiko ah oo ay ku leeyihiin daroogada sababtoo ah hantideeda aan it-inic
- Miisaanka Molecular: 10,000 ~ 1,000,000
- Goobta Gel: 40 ~ 90 ℃
- Qoraal gariir ah: 360 ℃
Hydroxypropylylulosol methylcelrellose (HPMC) Dawooyinka Farfaduhu waa Farsamo-dawo-ka-saarka daawooyinka iyo dheeriga ah, kaas oo loo isticmaali karo sidii dhumuc weyn, kala firidhsan, emulsifier iyo wakiilka sameynta filimka.
Saldhicirka unugyada 'iscricell celter' wuxuu ka kooban yahay bylulose (USP, EP, BP) iyo sedex nooc oo ku saabsan kaydinta hydroxyprose (hypromellose) mid kasta oo laga heli karo wax badan oo ka mid ah proces viscosity.hpmc ayaa laga soo qaatay dib-u-habeyn Linter Cotter iyo Pulp Pulp, oo la kulmay dhammaan shuruudaha USP, EP, BP, oo ay weheliso Kosher iyo shacal.
Nidaamka wax soosaarka, suufka dabiiciga ah ee dabiiciga ah waxaa lagu dadajiyaa methyl chloride ama isku darka methyl chloride iyo pretylne chloride iyo propylene oxide si ay u sameeyaan biyo-ku-milma, celyen non-onic celtel. Ma jiro ilo xayawaan ah oo loo adeegsado soo saarista HPMC.HpMC-ka waxaa loo isticmaali karaa inuu yahay shandad loogu talagalay foomamka qiyaasta qiyaasta adag sida kiniinnada iyo granules. Waxay kaloo u adeegtaa shaqooyin kala duwan, tusaalooyin, kor u qaadida haynta biyaha, qaro, u dhaqma sidii isbadal ilaalin ah sababtuna tahay nashaadkeeda dusha sare, sii daayaynta, iyo abuuritaanka filimka.
SETICCELL HPMC waxay bixisaa shaqooyin kala duwan sida haynta biyaha, colloid colled, waxqabadka dusha sare, siidaynta joogtada ah. Waa xarun aan inic ahayn u adkaysata si loo saleeyo oo lagu xasiliyo tiro aad u badan. Codsiyada caadiga ah ee HPMC-da waa inay ku qoran yihiin foomamka qiyaasta qiyaasta adag sida kiniinnada iyo granules ama cufan ee codsiyada dareeraha ah.
Farma HPMC waxay ku timaadaa isku-darka viscosity 3 ilaa 200,000 CPS, waxaana si weyn loogu isticmaali karaa daboolida kiniiniga, granulaalga, xayiraada, xayiraada, xasilinta iyo samaynta kaabsalka HPMC ee HPMC.
Qeexitaanka kiimikada
| Hantpromellose Cayimid | 60E (2910) | 65f (2906) | 75k (2208) |
| Heerkulka Gel (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (wt%) | 28.0-30.0 | 27.0-30.0 | 19.24.0.0 |
| Hydroxyproxy (wt%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity (CPS, 2% xalka) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Fasalka wax soo saarka
| Hantpromellose Cayimid | 60E (2910) | 65f (2906) | 75k (2208) |
| Heerkulka Gel (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (wt%) | 28.0-30.0 | 27.0-30.0 | 19.24.0.0 |
| Hydroxyproxy (wt%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity (CPS, 2% xalka) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Isticmaal
Darajooyinka Fasalka HPMC waxay awood u siisaa soosaarka qaababka sii-deynta ee la xakameynayo oo ay ku habboon yihiin habka loo isticmaalo kiniiniga kiniiniga ee ugu badan ee loo isticmaalo. Fasalka PHESA waxay bixisaa qulqulka budada ah ee wanaagsan, isku xirnaan la'aanta, iyo isku-darka, taasoo ka dhigeysa inay si fiican ugu habboon yihiin cadaadiska tooska ah.
| Codsiyada Lacagta Lacagta Lacagta | Pharava Fasalka HPMC | Qiyaas daawo |
| Caano badan | 75k4000,75k100000 | 3-30% |
| Kareemo, gels | 60E4000,75k4000 | 1-5% |
| Diyaarinta OphthalMic | 60E4000 | 01.-0.5% |
| Isha daahitaanka indhaha | 60E4000 | 0.1-0.5% |
| Ka hakinta wakiilka | 60E4000, 75k4000 | 1-2% |
| Antikons | 60E4000, 75k4000 | 1-2% |
| Kiniiniyada ayaa dhigay | 60E5, 60E15 | 0.5-5% |
| Guusha qoyan ee heshiisku | 60E5, 60E15 | 2-6% |
| Jaakadaha kiniiniga | 60E5, 60E15 | 0.5-5% |
| La xakameeyay matrix | 75k100000,75k15000 | 20-55% |
Astaamaha iyo dheefaha
- Waxay hagaajisaa astaamaha qulqulka badeecada
- waxay yareysaa waqtiyada waxqabadka
- is-isku mid ah, tafatirka kala goynta xasilloon
- Waxay hagaajisaa isku xirnaanta waxyaabaha ku jira
- waxay yareysaa qarashka wax soo saarka
- Hagaaji xoogga khafiifka ah ka dib marka labanlaab labanlaab ah (roller xisaabinta)
Ka iibsi
Xirmooyinka caadiga ah waa 25kg / durbaan
20'fcl: 9 tan oo la dubay; 10 ton oo aan la dulqaadan karin.
40'fcl: 18 tan oo la dubay; 20 ton oo aan loo dulqaadan karin Ganacsadeena waxaa loo dhoofiyay Mareykanka, Boqortooyada Midowday iyo wixii la mid ah, ku raaxeysiga caannimada weyn ee warshadda ay ka dhigto hot-iibka ah Oo annaguna waxaan kuu xirxiran karnaa adiga shakhsi ahaan markaad iibsanayso.
Warshadda waxay sameeyeen iibka kululChina HPMC Kist kiimiko iyo budada HPMC, Isku-darka wax soo saarka soosaarka waaxyaha ganacsiga shisheeyaha, waxaan dammaanad ka qaadayn karnaa gaarsiinta waxyaabaha saxda ah meesha saxda ah, kaas oo ay taageerayaan awooda soosaarka badan, tayada wax soo saarka ee awoodda leh, tayada isdaba joog ah, waxyaabaha la kala soocayo Xakamaynta isbeddelka warshadaha iyo sidoo kale qaan gaadhnimadayada ka hor iyo ka dib adeegyada iibka. Waxaan jeclaan lahayn inaan kula wadaagno fikradaheena oo aan soo dhaweyno faallooyinkaaga iyo su'aalahaaga.
