Nambarka Isticmaalaha ee wanaagsan ee kiimikada Dhismaha ee Qabad u yareeysa
Bartilmaameedkayagu waa inuu ahaadaa mid lagu xoojinayo oo la wanaajiyo tayada sare iyo adeegga badeecada hadda, waqtigaas had iyo jeer abuuro wax soo saarka macaamiisha ee 'hydroxypropyl hydroxyl' by by by by cvmc, oo aan si joogto ah ugu soo dhaweynno macaamiisha muddada-dheer iyo sidoo kale horumarka labada dhinac.
Bartilmaameedkayagu waa inuu ahaadaa mid la xoojinayo oo la wanaajiyo tayada sare iyo adeegga badeecada hadda jirta, waqtigaas had iyo jeer abuuro alaabooyin cusub oo lagu qanco wicitaanada macaamiisha kala duwan ee loogu talagalayShiinaha HPMC iyo hydroxypropyl methyl bylulose, Sababtuna tahay isbeddelada isbedelka ee arimahan, waxaan ku lug yeelanaynaa nafteena ganacsiga ganacsiga oo ay ku jiraan dadaallo heellan iyo heer sare. Waxaan ilaalinay jadwalka gudbinta waqtigeeda, naqshadeynta hal-abuurka, tayada iyo daah-furnaanta macaamiisheenna. Moto waa in aan soo gudbino badeecad tayo leh waqti cayiman.
Sharraxaadda Wax soo saarka
Hydroxypropyl bylule (hpmc)
Qaaciddada molika
Hab-daran (hydroxypropythythylcellosure: HPMC) Beddelka nooca 2910, 2906, 2208 (USP)
Guryaha jireed
- cad ama budada cad ee huruudda ah
- Ku milatarida isku dhafka ah ama aqueous
- Sameynta filim hufan oo hufan markii xalka ka saar
- Wax falcelin kiimiko ah oo ay ku leeyihiin daroogada sababtoo ah hantideeda aan it-inic
- Miisaanka Molecular: 10,000 ~ 1,000,000
- Goobta Gel: 40 ~ 90 ℃
- Qoraal gariir ah: 360 ℃
Hydroxypropylylulosol methylcelrellose (HPMC) Dawooyinka Farfaduhu waa Farsamo-dawo-ka-saarka daawooyinka iyo dheeriga ah, kaas oo loo isticmaali karo sidii dhumuc weyn, kala firidhsan, emulsifier iyo wakiilka sameynta filimka.
Saldhicirka unugyada 'bether' (USP), USP, EP, BP, CP, BP, CP, BP, oo la kulmay dhammaan shuruudaha loo yaqaan 'USP', ee EP, BP, oo ay weheliso Kosher, oo ay weheliso Kosher iyo shahaadada xalaasha.
Nidaamka wax soosaarka, suufka dabiiciga ah ee dabiiciga ah waxaa lagu dadajiyaa methyl chloride ama isku darka methyl chloride iyo pretylne chloride iyo propylene oxide si ay u sameeyaan biyo-ku-milma, celyen non-onic celtel. Ma jiro ilo xayawaan ah oo loo adeegsado soo saarista HPMC.HpMC-ka waxaa loo isticmaali karaa inuu yahay shandad loogu talagalay foomamka qiyaasta qiyaasta adag sida kiniinnada iyo granules. Waxay kaloo u adeegtaa shaqooyin kala duwan, tusaalooyin, kor u qaadida haynta biyaha, qaro, u dhaqma sidii isbadal ilaalin ah sababtuna tahay nashaadkeeda dusha sare, sii daayaynta, iyo abuuritaanka filimka.
SETICCELL HPMC waxay bixisaa shaqooyin kala duwan sida haynta biyaha, colloid colled, waxqabadka dusha sare, siidaynta joogtada ah. Waa xarun aan inic ahayn u adkaysata si loo saleeyo oo lagu xasiliyo tiro aad u badan. Codsiyada caadiga ah ee HPMC-da waa inay ku qoran yihiin foomamka qiyaasta qiyaasta adag sida kiniinnada iyo granules ama cufan ee codsiyada dareeraha ah.
Farma HPMC waxay ku timaadaa isku-darka viscosity 3 ilaa 200,000 CPS, waxaana si weyn loogu isticmaali karaa daboolida kiniiniga, granulaalga, xayiraada, xayiraada, xasilinta iyo samaynta kaabsalka HPMC ee HPMC.
Qeexitaanka kiimikada
| Hantpromellose Cayimid | 60E (2910) | 65f (2906) | 75k (2208) |
| Heerkulka Gel (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (wt%) | 28.0-30.0 | 27.0-30.0 | 19.24.0.0 |
| Hydroxyproxy (wt%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity (CPS, 2% xalka) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Fasalka wax soo saarka
| Hantpromellose Cayimid | 60E (2910) | 65f (2906) | 75k (2208) |
| Heerkulka Gel (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (wt%) | 28.0-30.0 | 27.0-30.0 | 19.24.0.0 |
| Hydroxyproxy (wt%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity (CPS, 2% xalka) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Isticmaal
Darajooyinka Fasalka HPMC waxay awood u siisaa soosaarka qaababka sii-deynta ee la xakameynayo oo ay ku habboon yihiin habka loo isticmaalo kiniiniga kiniiniga ee ugu badan ee loo isticmaalo. Fasalka PHESA waxay bixisaa qulqulka budada ah ee wanaagsan, isku xirnaan la'aanta, iyo isku-darka, taasoo ka dhigeysa inay si fiican ugu habboon yihiin cadaadiska tooska ah.
| Codsiyada Lacagta Lacagta Lacagta | Pharava Fasalka HPMC | Qiyaas daawo |
| Caano badan | 75k4000,75k100000 | 3-30% |
| Kareemo, gels | 60E4000,75k4000 | 1-5% |
| Diyaarinta OphthalMic | 60E4000 | 01.-0.5% |
| Isha daahitaanka indhaha | 60E4000 | 0.1-0.5% |
| Ka hakinta wakiilka | 60E4000, 75k4000 | 1-2% |
| Antikons | 60E4000, 75k4000 | 1-2% |
| Kiniiniyada ayaa dhigay | 60E5, 60E15 | 0.5-5% |
| Guusha qoyan ee heshiisku | 60E5, 60E15 | 2-6% |
| Jaakadaha kiniiniga | 60E5, 60E15 | 0.5-5% |
| La xakameeyay matrix | 75k100000,75k15000 | 20-55% |
Astaamaha iyo dheefaha
- Waxay hagaajisaa astaamaha qulqulka badeecada
- waxay yareysaa waqtiyada waxqabadka
- is-isku mid ah, tafatirka kala goynta xasilloon
- Waxay hagaajisaa isku xirnaanta waxyaabaha ku jira
- waxay yareysaa qarashka wax soo saarka
- Hagaaji xoogga khafiifka ah ka dib marka labanlaab labanlaab ah (roller xisaabinta)
Ka iibsi
Xirmooyinka caadiga ah waa 25kg / durbaan
20'fcl: 9 tan oo la dubay; 10 ton oo aan la dulqaadan karin.
40'fcl: 18 tan oo la dubay; 20 to to tongeleted. Joht bartilmaameedka waa inuu ahaadaa mid la xoojinayo oo kor loogu qaado tayada sare iyo adeegga badeecada hadda, markaas waxaan si daacad ah ugu soo dhaweyneynaa macaamiisha si ay ula tashadeen macaamiisha muddada-dheer iyo sidoo kale horumarka labada dhinac.
Nadiifinta Isticmaalaha wanaagsan ee loogu talagalayShiinaha HPMC iyo hydroxypropyl methyl bylulose, Sababtuna tahay isbeddelada isbedelka ee arimahan, waxaan ku lug yeelanaynaa nafteena ganacsiga ganacsiga oo ay ku jiraan dadaallo heellan iyo heer sare. Waxaan ilaalinay jadwalka gudbinta waqtigeeda, naqshadeynta hal-abuurka, tayada iyo daah-furnaanta macaamiisheenna. Moto waa in aan soo gudbino badeecad tayo leh waqti cayiman.
