Iibinta kulul ee HPMC ee madaafiicda, budada ah, oo ah budada loo yaqaan 'esstyty budada' k200m '
Waxaan ku faraxsanahay qanacsanaanta macmiilka weyn iyo aqbalaadda ballaaran ee ay ugu wacan tahay raadinta tayada sare ee badeecada iyo dayactirka moodada, oo ah budada loo yaqaan 'powtyc', oo ah budada loo yaqaan 'powtyc', oo ah nuxurka nadaafadda ee k200m, yoolkeenna ugu dambeeya waa "in la isku dayo ugu fiican, in la isku dayo. Noqo kan ugu fiican ". Fadlan xor u tahay inaad nala soo xiriirto haddii aad wax shuruud ah ku qabtid.
Waxaan ku faraxsanahay qanacsanaanta macmiilka weyn iyo aqbalaadda ballaaran ee ay sabab u tahay raadinta joogtada ah ee tayada sare ee badeecadaha iyo dayactirkaShiinaha HPMC iyo Hydroxypropyl methylrcellulose, Iyada oo dadaal ay tahay in lagu sii wado xawaaraha isbeddelka adduunka, waxaan had iyo jeer ku dadaalaynaa inaan la kulanno baahiyaha macaamiisha. Haddii aad rabto inaad horumariso wax soo saar kale oo cusub, waan kuu habayn karnaa adiga. Haddii aad dareento dulsaar ka mid ah badeecadeena ama aad rabto inaad horumariso alaabooyin cusub, fadlan xor u noqo inaad nala soo xiriirto. Waxaan rajeyneynaa inaan sameyno xiriir ganacsi oo guul leh oo lala yeesho macaamiisha adduunka oo dhan.
Sharraxaadda Wax soo saarka
Hydroxypropyl bylule (hpmc)
Qaaciddada molika
Hab-daran (hydroxypropythythylcellosure: HPMC) Beddelka nooca 2910, 2906, 2208 (USP)
Guryaha jireed
- cad ama budada cad ee huruudda ah
- Ku milatarida isku dhafka ah ama aqueous
- Sameynta filim hufan oo hufan markii xalka ka saar
- Wax falcelin kiimiko ah oo ay ku leeyihiin daroogada sababtoo ah hantideeda aan it-inic
- Miisaanka Molecular: 10,000 ~ 1,000,000
- Goobta Gel: 40 ~ 90 ℃
- Qoraal gariir ah: 360 ℃
Hydroxypropylylulosol methylcelrellose (HPMC) Dawooyinka Farfaduhu waa Farsamo-dawo-ka-saarka daawooyinka iyo dheeriga ah, kaas oo loo isticmaali karo sidii dhumuc weyn, kala firidhsan, emulsifier iyo wakiilka sameynta filimka.
Saldhicirka unugyada 'iscricell celter' wuxuu ka kooban yahay bylulose (USP, EP, BP) iyo sedex nooc oo ku saabsan kaydinta hydroxyprose (hypromellose) mid kasta oo laga heli karo wax badan oo ka mid ah proces viscosity.hpmc ayaa laga soo qaatay dib-u-habeyn Linter Cotter iyo Pulp Pulp, oo la kulmay dhammaan shuruudaha USP, EP, BP, oo ay weheliso Kosher iyo shacal.
Nidaamka wax soosaarka, suufka dabiiciga ah ee dabiiciga ah waxaa lagu dadajiyaa methyl chloride ama isku darka methyl chloride iyo pretylne chloride iyo propylene oxide si ay u sameeyaan biyo-ku-milma, celyen non-onic celtel. Ma jiro ilo xayawaan ah oo loo adeegsado soo saarista HPMC.HpMC-ka waxaa loo isticmaali karaa inuu yahay shandad loogu talagalay foomamka qiyaasta qiyaasta adag sida kiniinnada iyo granules. Waxay kaloo u adeegtaa shaqooyin kala duwan, tusaalooyin, kor u qaadida haynta biyaha, qaro, u dhaqma sidii isbadal ilaalin ah sababtuna tahay nashaadkeeda dusha sare, sii daayaynta, iyo abuuritaanka filimka.
SETICCELL HPMC waxay bixisaa shaqooyin kala duwan sida haynta biyaha, colloid colled, waxqabadka dusha sare, siidaynta joogtada ah. Waa xarun aan inic ahayn u adkaysata si loo saleeyo oo lagu xasiliyo tiro aad u badan. Codsiyada caadiga ah ee HPMC-da waa inay ku qoran yihiin foomamka qiyaasta qiyaasta adag sida kiniinnada iyo granules ama cufan ee codsiyada dareeraha ah.
Farma HPMC waxay ku timaadaa isku-darka viscosity 3 ilaa 200,000 CPS, waxaana si weyn loogu isticmaali karaa daboolida kiniiniga, granulaalga, xayiraada, xayiraada, xasilinta iyo samaynta kaabsalka HPMC ee HPMC.
Qeexitaanka kiimikada
| Hantpromellose Cayimid | 60E (2910) | 65f (2906) | 75k (2208) |
| Heerkulka Gel (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (wt%) | 28.0-30.0 | 27.0-30.0 | 19.24.0.0 |
| Hydroxyproxy (wt%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity (CPS, 2% xalka) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Fasalka wax soo saarka
| Hantpromellose Cayimid | 60E (2910) | 65f (2906) | 75k (2208) |
| Heerkulka Gel (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (wt%) | 28.0-30.0 | 27.0-30.0 | 19.24.0.0 |
| Hydroxyproxy (wt%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity (CPS, 2% xalka) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Isticmaal
Darajooyinka Fasalka HPMC waxay awood u siisaa soosaarka qaababka sii-deynta ee la xakameynayo oo ay ku habboon yihiin habka loo isticmaalo kiniiniga kiniiniga ee ugu badan ee loo isticmaalo. Fasalka PHESA waxay bixisaa qulqulka budada ah ee wanaagsan, isku xirnaan la'aanta, iyo isku-darka, taasoo ka dhigeysa inay si fiican ugu habboon yihiin cadaadiska tooska ah.
| Codsiyada Lacagta Lacagta Lacagta | Pharava Fasalka HPMC | Qiyaas daawo |
| Caano badan | 75k4000,75k100000 | 3-30% |
| Kareemo, gels | 60E4000,75k4000 | 1-5% |
| Diyaarinta OphthalMic | 60E4000 | 01.-0.5% |
| Isha daahitaanka indhaha | 60E4000 | 0.1-0.5% |
| Ka hakinta wakiilka | 60E4000, 75k4000 | 1-2% |
| Antikons | 60E4000, 75k4000 | 1-2% |
| Kiniiniyada ayaa dhigay | 60E5, 60E15 | 0.5-5% |
| Guusha qoyan ee heshiisku | 60E5, 60E15 | 2-6% |
| Jaakadaha kiniiniga | 60E5, 60E15 | 0.5-5% |
| La xakameeyay matrix | 75k100000,75k15000 | 20-55% |
Astaamaha iyo dheefaha
- Waxay hagaajisaa astaamaha qulqulka badeecada
- waxay yareysaa waqtiyada waxqabadka
- is-isku mid ah, tafatirka kala goynta xasilloon
- Waxay hagaajisaa isku xirnaanta waxyaabaha ku jira
- waxay yareysaa qarashka wax soo saarka
- Hagaaji xoogga khafiifka ah ka dib marka labanlaab labanlaab ah (roller xisaabinta)
Ka iibsi
Xirmooyinka caadiga ah waa 25kg / durbaan
20'fcl: 9 tan oo la dubay; 10 ton oo aan la dulqaadan karin.
40'fcl: 18 tan oo la dubay; 20 ton oo aan loo dulqaadan karin. Waxa ugu fiican, inuu noqdo kan ugu fiican ". Fadlan xor u tahay inaad nala soo xiriirto haddii aad wax shuruud ah ku qabtid.
Iibinta kulul ee loogu talagalayShiinaha HPMC iyo Hydroxypropyl methylrcellulose, Iyada oo dadaal ay tahay in lagu sii wado xawaaraha isbeddelka adduunka, waxaan had iyo jeer ku dadaalaynaa inaan la kulanno baahiyaha macaamiisha. Haddii aad rabto inaad horumariso wax soo saar kale oo cusub, waan kuu habayn karnaa adiga. Haddii aad dareento dulsaar ka mid ah badeecadeena ama aad rabto inaad horumariso alaabooyin cusub, fadlan xor u noqo inaad nala soo xiriirto. Waxaan rajeyneynaa inaan sameyno xiriir ganacsi oo guul leh oo lala yeesho macaamiisha adduunka oo dhan.
