Qiimaha hooseeya ee viscosity hydroxyethyl cellulose HEC ee isticmaalka saliidda
Diiradayadayadu waa inay noqotaa mid xoojinaysa oo kor u qaadaysa tayada iyo hagaajinta alaabada hadda jirta, isla markaana si joogto ah u abuurto alaab cusub si ay ula kulmaan macaamiisha gaarka ah 'qiimaha hooseeya ee viscosity hydroxyethyl cellulose HEC ee isticmaalka saliidda, Waxaan ixtiraameynaa maamulahayaga asaasiga ah ee daacadnimada xagga ganacsiga, mudnaanta adeegyada waxaanan ku dadaali doonaa inaan siino dukaameeystayaasha xalal tayo sare leh iyo adeeg heersare ah.
Diiradayadayadu waa inay ahaato midaynta iyo kor u qaadida tayada iyo dayactirka alaabooyinka hadda jira, inta lagu guda jiro si joogto ah u abuurista alaabooyin cusub si loo daboolo baahiyaha macaamiisha gaarka ahShiinaha HEC iyo Hydroxyethyl CelluloseShirkaddayadu waxay tixgelisaa "qiimaha macquulka ah, tayada sare leh, waqti wax soo saar hufan iyo adeeg iibka ka dib" sida our mabda'a. Waxaan rajeyneynaa inaan la shaqeyno macaamiil badan si loo horumariyo faa'iidooyinka mustaqbalka. Ku soo dhawoow inaad nala soo xidhiidho.
Sharaxaada Alaabta
Hydroxypropyl Methyl Cellulose (HPMC)
Qaanuunka molecular
Hypromellose (Hydroxypropylmethylcellulose: HPMC) beddelka nooca 2910, 2906, 2208 (USP)
Guryaha Jirka
- budo cad oo cad ama huruud ah
- Ku milmay dareere organic ama aqueous qasan
- Samaynta filim hufan marka dareeraha laga saaro
- Wax fal-celin kiimikaad ah ma leh daroogada sababtoo ah hantideeda aan-ionic ahayn
- Miisaanka Molecular: 10,000 ~ 1,000,000
- Gel dhibic: 40 ~ 90 ℃
- Barta shidista tooska ah: 360 ℃
Hydroxypropyl Methylcellulose (HPMC) Farmashiisku waa Heerarka Dawada Hypromellose iyo kaabis, kaas oo loo isticmaali karo sidii dhumuc, kala-firdhiye, emulsifier iyo wakiilka filim-samaynta.
QualiCell Cellulose ether waxay ka kooban tahay methyl cellulose (USP, EP,BP,CP) iyo saddex nooc oo beddelka ah ee hydroxypropyl methyl cellulose (hypromellose USP, EP, BP, CP) mid kasta oo la heli karo dhowr darajooyin kala duwan in viscosity.HPMC alaabta waxaa laga soo qaatay dabiiciga ah la safeeyey. suufka suufka iyo saxarka alwaax, buuxinaya dhammaan shuruudaha USP, EP, BP, oo ay la socdaan Koosher iyo Shahaadooyin Xalaal ah.
Habka wax-soo-saarka, suufka dabiiciga ah ee aadka loo sifeeyay waxaa lagu nadiifiyaa methyl chloride ama isku darka methyl chloride iyo propylene oxide si loo sameeyo biyo-milmi kara, eter-ka cellulose aan-ionic ahayn. Ma jiraan wax xoolo ah oo loo isticmaalo soo saarista HPMC.HPMC waxa loo isticmaali karaa xidhe ahaan foomamka qiyaasta qiyaasta adag sida kiniiniyada iyo granules. Waxa kale oo ay u adeegtaa hawlo kala duwan, tusaale ahaan, kor u qaadida haynta biyaha, dhumucda, u dhaqmidda sida kolloid ilaalin ah sababtoo ah dhaqdhaqaaqa dusha sare, sii daynta joogtada ah, iyo samaynta filimada.
QualiCell HPMC waxay bixisaa hawlo kala duwan sida haynta biyaha, kolloid ilaalinta, dhaqdhaqaaqa dusha sare, sii daynta joogtada ah. Waa iskudhis aan-ionic ahayn oo adkaysi u leh inay milixdu soo saarto oo ku xasilo inta u dhaxaysa pH-ballaaran. Codsiyada caadiga ah ee HPMC waxay ku xidhaan foomamka qiyaasta qiyaasta adag sida kiniiniyada iyo granules ama dhumucyada codsiyada dareeraha ah.
Pharma HPMC waxay u dhaxaysaa 3 ilaa 200,000 cps, waxaana si balaadhan loogu isticmaali karaa daahan kiniiniga ah, granulation, binder, dhumuc weyn, xasiliye iyo samaynta kaabsulka HPMC qudaarta.
Tilmaamaha Kiimikada
| Hypromellose Tilmaamid | 60E (2910) | 65F (2906) | 75K (2208) |
| Heerkulka jel (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity (cps, 2% Xalka) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000, 100000, 150000, 200000 | ||
Heerka Alaabta
| Hypromellose Tilmaamid | 60E (2910) | 65F (2906) | 75K (2208) |
| Heerkulka jel (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity (cps, 2% Xalka) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000, 100000, 150000, 200000 | ||
Codsiga
Fasalka Pharma HPMC waxa uu awood u leeyahay soo saarista qaabaynta siidaynta la kantaroolay iyada oo la fududaynayo habka aadka loo isticmaalo kiniinka xidhidhiyaha. Fasalka Pharma wuxuu bixiyaa qulqulka budada wanaagsan, lebbiska tusmada, iyo isku-buufinta, taasoo ka dhigaysa inay ku habboon yihiin isku-buufin toos ah.
| Codsiga Pharma Excipients | Heerka Pharma HPMC | Qiyaasta |
| Bulk Laxative | 75K4000,75K100000 | 3-30% |
| Kareemada, jel | 60E4000,75K4000 | 1-5% |
| Diyaarinta Indhaha | 60E4000 | 01.-0.5% |
| Diyaarinta Dhibcaha Indhaha | 60E4000 | 0.1-0.5% |
| Wakiilka Joojinta | 60E4000, 75K4000 | 1-2% |
| Antacids | 60E4000, 75K4000 | 1-2% |
| Kiniinnada Binder | 60E5, 60E15 | 0.5-5% |
| Convention Qoyan Granulation | 60E5, 60E15 | 2-6% |
| Dahaarka kiniinka | 60E5, 60E15 | 0.5-5% |
| Matrix siidaynta la xakameeyey | 75K100000,75K15000 | 20-55% |
Tilmaamaha iyo Faa'iidooyinka
- Waxay hagaajisaa sifooyinka socodka alaabta
- Waxay yaraysaa waqtiyada habaynta
- La mid ah, profiles kala diri deggan
-Waxay wanaajisaa isku midnimada nuxurka
- Waxay dhimaysaa kharashka wax soo saarka
- Waxay xajistaa awoodda xajinta ka dib habka labajibbaaran ee is-jiidashada
Baakadaha
Xirmooyinka caadiga ah waa 25kg/durbaan
20'FCL: 9 tan oo paletteed leh; 10 tan oo aan miir lahayn.
40'FCL: 18 tan oo leh palletized; 20 tan oo aan miir lahayn.
Diiradayadayadu waa inay noqotaa mid xoojinaysa oo kor u qaadaysa tayada iyo hagaajinta alaabada hadda jirta, isla markaana si joogto ah u abuurto alaab cusub si ay ula kulmaan macaamiisha gaarka ah 'qiimaha hooseeya ee viscosity hydroxyethyl cellulose HEC ee isticmaalka saliidda, Waxaan ixtiraameynaa maamulahayaga asaasiga ah ee daacadnimada xagga ganacsiga, mudnaanta adeegyada waxaanan ku dadaali doonaa inaan siino dukaameeystayaasha xalal tayo sare leh iyo adeeg heersare ah.
Qiimaha hooseeya ee Shiinaha HEC iyo Hydroxyethyl cellulose, Shirkaddayadu waxay tixgelinaysaa "qiimaha macquulka ah, tayada sare leh, waqti wax soo saar hufan iyo adeegga iibka ka dib" sida mabda'ayada. Waxaan rajeyneynaa inaan la shaqeyno macaamiil badan si loo horumariyo faa'iidooyinka mustaqbalka. Ku soo dhawoow inaad nala soo xidhiidho.
