HydroxyproPypropyL methylcelllulo le hydroxeeyl cellulosese

HydroxypropypropyLese (HPMC)'me hydroxethyl cellulosese (Hec) ke litlolo tse peli tsa bohlokoa tsa cellulose li sebelisoa haholo indasteri e fapaneng ka lebaka la thepa ea tsona e ikhethang. Le ha bobeli ba bobeli ba tsoa ho Cellloulose, ba na le likarolo tse ikhethileng tsa lik'hemik'hale le lits'ebetso tse fapaneng.

1. Selelekela ho li-dirivanals tsa cellulose:
Celllouse ke Polysaccharide ea Sebaka sa Polycse ea Linear Units ea Glucose e hokahantsoeng ke Β (1 → Mefuta e meng ea cellulose e fumanoa ka ho lekanya ka lik'hemik'hale ho ntlafatsa cellulose ea ho ntlafatsa thepa kapa ho hlahisa litsebi tse ncha. HPMC le hec ke lisebo tse peli tse entsoeng hantle haholo ho indastering ho tloha meraking ho ea kaho.

2. Synthesis:
HPMC e entsoe ka celdoulose e etsang celloulose e nang le pokello ea khomo ea ho ngola tsa hydroxypropyl ho hlahisa lihlopha tsa methyl. Sena se fella ka hore ho ka etsahala ka likheo tsa Hydroyl ka ketane ea celdroulo, ea tenyetsang sehlahisoa se nang le linyeoe tse ntlafalitsoeng le tsa lifilimi.

SHIC, ka lehlakoreng le leng, e hlahisoa ka celdulose le atylene ho kenyelletsa lihlopha tsa hydroyethyl. Tekanyo ea sebaka (DS) ka bobeli HPMC le hec e ka laoloa ke ho fetola maemo a boitšoaro, a ama thepa ea bona e kang ho etsa lintho.

3. Sebopeho sa lik'hemik'hale:
HPMC LE HEC e fapana ho mefuta ea lihlopha tse bonoang tse hokahaneng le mokokotlo oa selefouno. HPMC e na le li-hydropyproPyL le lihlopha tsa methyl, ha hec a le hydroythyl lihlopha tsa hydroythyl. Libaka tsena li fana ka litšobotsi tse ikhethang ho e 'ngoe le e' ngoe e matlafatsang likotlong tse fapaneng.

4. Thepa ea 'mele:
Ka bobeli HPMC le hec ke polymiso ea metsi e qhibilihang metsi ka thepa e ntle ea metsi. Leha ho le joalo, ba bontša phapang ka litsietsi, bophahamo ba hydration le bokhoni ba ho etsa lifilimi. HPMC hangata e na le liketsahalo tse phahameng tse bapisoang le Hec libakeng tse tšoanang, li etsa hore e be e loketseng likopo tse hlokang ho hloka likopo tse ngata.

Ntle le moo, HPMC e hlakisa haholoanyane le lifilimi tse kopaneng haholoanyane ka lebaka la litlolo tsa eona tsa methyl, athe Hec e theha softer le lifilimi tse boima haholo. Phapang ena ka har'a thepa ea lifilimi e etsa hore motho e mong le e mong a behe boikarabello bo itseng bakeng sa lits'ebetso tse khethehileng tsa meriana, lihlahisoa tsa tlhokomelo le indasteri ea motho ka mong.

5. Likopo:
5.1 indasteri ea pharmaceutical:
Ka bobeli HPMC le HPMC le HC bo sebelisoa haholo ka mekhoa ea meromatiocticarical e le lithuna, lithibela le baemeli ba koahelang lifilimi. Li ntlafatsa boleng ba matlapi, laola ho kenngoa lithethefatsi, 'me li ntlafatsa molodimong ea metsi. HPMC e khetholloa bakeng sa lipalo tsa ho lokolloa ka lebaka la sekhahla sa eona sa Hydaster, ha hec e sebelisoa hangata ka likharabe tsa mahlo le ho lumellana ha metsi a khale.

6.2 indasteri ea kaho:
Indastering ea kaho,HpmcMmeHecba hiriloe e le litlatsetso lisebelisoa tse thehiloeng ho saense, joalo ka lefu, ho korola le ho iphetetsa. Ba ntlafatsa ho ba le boikoetliso, ho boloka metsi le ho tšoarella, ho fella ka ts'ebetso e ntlafalitsoeng le ho tšoarella ha sehlahisoa sa ho qetela. HPMC e khetholloa hangata bakeng sa bophahamo ba eona bo phahameng ba metsi, bo fokolisang ho senyeha le ho ntlafatsa nako.

5.3 Lihlahisoa tsa tlhokomelo ea motho:
Litlaleho tsena ka bobeli li fumana lits'ebetso ka lihlahisoa tsa tlhokomelo e kang shampoos, litlolo le litlolo e le li-emmorifurs. Hec o kenyelletsa kotlo e boreleli ebile e boreleli ea ho hlophisa, e etsa hore e loketse lihlahisoa tsa tlhokomelo ea moriri le litlolo tsa letlalo. HPMC, Ka thepa ea eona e phahameng haholo ea lifilimi, e sebelisoa ho sinscerens le lifono tse nang le litlolo tse hlokang ho hanyetsa metsi le ho apara nako e telele.

5.4 indasteri ea lijo:
Indastering ea lijo, HPMC le hec e le mahlahahlaha le litlolo libukeng tse fapaneng ho kenyelletsa le batho ba tsoang liso. Ba ntlafatsa litsebi, thibela Syneresis, 'me ba ntlafatsa litšobotsi tsa maikutlo a mefuta ea lijo. HPMC hangata e khetholloa bakeng sa ho hlaka le botsitso ba mocheso, ho etsa hore e be loketse likopo li hlokang likopo tse hlokang kelello le tse tsitsitseng.

6. Qeto:
Hydroxypropypropypropinyl methylcelllulose (HPMC) le hydroxeeyyl celdoulose (Hec) ke meaho e mengata ea lik'hemik'hale, thepa le lits'ebetso. Le ha bobeli le fana ka thepa ea ho etsa lintho tse ntle le ho etsa lifilimi, ba bontša phapang ea litsietsi, ho hlaka le ho hlaka le boitšoaro ba Hydration. Ho utloisisa liphapang tsena ho bohlokoa bakeng sa ho khetha ho etsa mesebetsi e itseng ho li-indasteri tse ikhethang ho indasteri, kaho, tlhokomelo ea motho le lijo. Joalokaha lipatlisiso li ntse li tsoela pele, ho be le liphetoho tse ling le likopo tsa lits'ila tsa litlolo tsa cellulose, li kenya letsoho bohlokoa ba bona ba likarolong tse fapaneng tsa indasteri.